Zobrazeno 1 - 10
of 10
pro vyhledávání: '"KEIKO O. SIMON"'
Autor:
Mammen P. Mammen, Pablo Tebas, Joseph Agnes, Mary Giffear, Kimberly A. Kraynyak, Elliott Blackwood, Dinah Amante, Emma L. Reuschel, Mansi Purwar, Aaron Christensen-Quick, Nieman Liu, Viviane M. Andrade, Julie Carter, Gabriella Garufi, Malissa C. Diehl, Albert Sylvester, Matthew P. Morrow, Patrick Pezzoli, Abhijeet J. Kulkarni, Faraz I. Zaidi, Drew Frase, Kevin Liaw, Hedieh Badie, Keiko O. Simon, Trevor R.F. Smith, Stephanie Ramos, Robert Spitz, Robert J. Juba, Jessica Lee, Michael Dallas, Ami Shah Brown, Jacqueline E. Shea, J. Joseph Kim, David B. Weiner, Kate E. Broderick, Jean D. Boyer, Laurent M. Humeau
BackgroundVaccines against SARS-CoV-2 are still urgently needed as only 5% of the global population has been vaccinated. Here we report the safety and immunogenicity of a DNA vaccine (INO-4800) targeting the full-length Spike antigen of SARS-CoV-2 wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65bb33f42e855f7d0b873b47add357f8
https://doi.org/10.1101/2021.05.07.21256652
https://doi.org/10.1101/2021.05.07.21256652
Publikováno v:
Journal of Biological Chemistry. 272:29380-29389
This study examines the interactions of alphavbeta3 and alpha5beta1 in the regulation of cell migration. Human embryonic kidney (HEK) 293 cells that express alpha5beta1 endogenously were transfected with alphavbeta3 and beta3 mutants, and their attac
Publikováno v:
Biochemical Society Transactions. 19:1065-1069
Autor:
Keiko O. Simon, Keith Burridge
Publisher Summary Integrins are major cell surface receptors that bind to various extracellular matrix proteins or to components on the surfaces of other cells. Since their discovery, a major function for integrins has been presumed to be the attachm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07dce7efcfe28268bdeb6e01216329d0
https://doi.org/10.1016/b978-0-08-091729-0.50008-5
https://doi.org/10.1016/b978-0-08-091729-0.50008-5
Autor:
JOHN ASHKENAS, DONALD R. BERTOLINI, MINA J. BISSELL, KEITH BURRIDGE, GINETTA COLLO, HELEN M. COOPER, CAROLINE H. DAMSKY, DOUGLAS W. DESIMONE, MARIANO J. ELICES, GUIDO GAIETTA, MARK D. HENS, MARKETTA HORMIA, THOMAS J. KUNICKI, THOMAS LALLIER, ANDREW J. NICHOLS, VITO QUARANTA, CARLA ROZZO, ZAVERIO M. RUGGERI, JAMES M. SAMANEN, MARTIN A. SCHWARTZ, KEIKO O. SIMON, JEFFREY W. SMITH, JEFFREY M. STADEL, LISA STARR, RICHARD N. TAMURA, ZENA WERB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f31243ef4a92cb6467e9cc0bb084172d
https://doi.org/10.1016/b978-0-08-091729-0.50004-8
https://doi.org/10.1016/b978-0-08-091729-0.50004-8
Publisher Summary Single proteins, either α-actinin or talin, form a bridge between actin and integrin. Interaction of actin with these two proteins may serve different functions in focal adhesions. In situ, there are structures that appear to be ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88d53a7860e6f377a7660b95fc34c923
https://doi.org/10.1016/s0070-2161(08)60781-9
https://doi.org/10.1016/s0070-2161(08)60781-9
Autor:
Fredrick M. Pavalko, Keiko O. Simon, Keith Burridge, Carol A. Otey, Christopher E. Turner, Glen H. Nuckolls
Publikováno v:
Cell differentiation and development : the official journal of the International Society of Developmental Biologists. 32(3)
Focal adhesions are regions of the plasma membrane where cells in tissue culture adhere strongly to the underlying extracellular matrix, and which at their cytoplasmic face serve to anchor bundles of actin microfilaments. They provide an experimental
Publikováno v:
Virology. 177(1)
The cytopathic effects of vesicular stomatitis virus (VSV) that result in the rounding of BHK21 cells have been studied. The results indicate that they are mediated by a sequential alteration in the distribution of the components of the cytoskeleton,
Autor:
Tebas, Pablo, Agnes, Joseph, Giffear, Mary, Kraynyak, Kimberly A, Blackwood, Elliott, Amante, Dinah, Reuschel, Emma, Liu, Neiman, Purwar, Mansi, Christensen-Quick, Aaron, Andrade, Viviane M, Carter, Julie, Garufi, Gabriella, Diehl, Malissa, Sylvester, Albert, Morrow, Matthew P, Pezzoli, Patrick P, Kulkarni, Abhijeet J, Zaidi, Faraz I, Frase, Drew, Liaw, Kevin, Patel, Ami, Buttigieg, Karen R, Ervin, John E, Pawlicki, Jan, Gillespie, Elisabeth, Maricic, Igor, Schultheis, Katherine, Badie, Hedieh, Herring, Timothy A, Simon, Keiko O, Smith, Trevor R F, Ramos, Stephanie, Spitz, Robert, Lee, Jessica, Dallas, Michael, Brown, Ami Shah, Shea, Jacqueline E, Kim, J Joseph, Weiner, David, Broderick, Kate, McMullan, Trevor, Boyer, Jean, Humeau, Laurent, Mammen Jr., Mammen P
Publikováno v:
Open Forum Infectious Diseases
Background DNA vaccines are safe, tolerable, elicit humoral and cellular responses, allow for repeated dosing over time, are thermostable at room temperature, and are easy to manufacture. We present a compilation of Phase 1 and Phase 2 data of Inovio
Autor:
David A. Cheresh
Integrins: Molecular and Biological Responses to the Extracellular Matrix will help basic, applied, and clinical researchers keep up with the explosion of literature on the integrin family of proteins. This volume extends material previously covered