Zobrazeno 1 - 10
of 593
pro vyhledávání: '"KEAP1/NRF2"'
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background The kidney is exceptionally vulnerable during sepsis, often resulting in sepsis-associated acute kidney injury (SA-AKI), a condition that not only escalates morbidity but also significantly raises sepsis-related mortality rates. C
Externí odkaz:
https://doaj.org/article/eb4893f5d0ce49bea708b18f95ed49a4
Autor:
Maria Maqsood, Raakia Anam Saeed, Muhammad Issa Khan, Muhammad Naeem Faisal, Hamna Anam Saeed, Gholamreza Abdi, Rana Muhammad Aadil
Publikováno v:
Journal of Agriculture and Food Research, Vol 18, Iss , Pp 101378- (2024)
Morus nigra fruit has therapeutic significance against several clinical manifestations due to polyphenols, flavonoids, and anthocyanins. This research aimed to investigate the antioxidative and anti-inflammatory effects of ultrasound-assisted ethanol
Externí odkaz:
https://doaj.org/article/8b28cf80de3e49b5a366425d3b34a51f
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e38958- (2024)
The prevention and treatment of hypobaric hypoxia brain injury (HHBI) remains an unprecedented challenge due to the complex oxidative stress response at the damage site. In this study, RuCO phthalocyanine compound (RuPc) and bovine serum albumin (BSA
Externí odkaz:
https://doaj.org/article/800759d457a44d188a3b6780ef6bffdd
Publikováno v:
Journal of Functional Foods, Vol 118, Iss , Pp 106290- (2024)
This study aimed to investigate the inhibitory effect of astragaloside IV (AS-IV) on enterovirus 71 (EV71)-induced pyroptosis. The results indicated that AST-IV inhibited EV71-induced pyroptosis in normal human gastric epithelial (GES-1) cells. There
Externí odkaz:
https://doaj.org/article/b1fd90a7f1184fbe9b78b6b1ab3ddc9f
Autor:
Ke-Gang Linghu, Tian Zhang, Guang-Tao Zhang, Peng Lv, Wen-Jun Zhang, Guan-Ding Zhao, Shi-Hang Xiong, Qiu-Shuo Ma, Ming-Ming Zhao, Meiwan Chen, Yuan-Jia Hu, Chang-Sheng Zhang, Hua Yu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 3, Pp 401-415 (2024)
Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) by Kelch-like ECH-associated protein 1 (Keap1) alkylation plays a central role in anti-inflammatory therapy. However, activators of Nrf2 through alkylation of Keap1-Kelch domain have no
Externí odkaz:
https://doaj.org/article/f75993c98ed24cf58861ad94efe72201
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-20 (2024)
Abstract Background A-to-I RNA editing is an abundant post-transcriptional modification event in hepatocellular carcinoma (HCC). Evidence suggests that adenosine deaminases acting on RNA 1 (ADAR1) correlates to oxidative stress that is a crucial fact
Externí odkaz:
https://doaj.org/article/3f2453feeb1140d38db502d5f23e2475
Autor:
Junchen Guo, Shanjie Wang, Xin Wan, Xiaoxuan Liu, Zeng Wang, Chenchen Liang, Zhenming Zhang, Ye Wang, Miao Yan, Pengyan Wu, Shaohong Fang, Bo Yu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Ferroptosis is a regulatory cell death process pivotal in myocardial ischemia–reperfusion (I/R) injury. However, the precise mechanism underlying myocardial ferroptosis remains less known. In this study, we investigated the pathophysiologi
Externí odkaz:
https://doaj.org/article/2819998bb411418ebd9bf339c2eefb30
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 10, p 356 (2024)
Background: As antioxidant and anti-inflammatory agents, carbonic anhydrase inhibitors can exert potentially useful therapeutic effects following central nervous system trauma, including intracerebral hemorrhage (ICH). However, the therapeutic effica
Externí odkaz:
https://doaj.org/article/696c7e61380b498885139ca3797c31e4
Autor:
Yan Chen, Yanan Zhao, Hao Lu, Weichen Zhang, Yanan Gai, Guanting Niu, Xiuhua Meng, Han Lv, Xiaoguo Qian, Xiaoqin Ding, Jian Chen
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Numerous studies have demonstrated that polysaccharides derived from chicory possess the ability to regulate host signaling and modify mucosal damage. Yet, the effect and mechanism of short-chain fructo-oligosaccharides (scFOS) on gastric mucosa rema
Externí odkaz:
https://doaj.org/article/a1f781912ab9452dadc6d81440bc2433
Publikováno v:
Journal of Traditional Chinese Medical Sciences, Vol 10, Iss 4, Pp 484-492 (2023)
Objective: To explore the effects and underlying mechanisms of Guilu Erxian glue (GLEXG) on oxidative damage in a mouse GC-1 spermatogonial (MGS) cell model. Methods: A cellular model for oxidative damage was created using MGS cells exposed to hydrog
Externí odkaz:
https://doaj.org/article/72e9690a0c07474987ed2413d8eda3dd