Zobrazeno 1 - 10 of 384 pro vyhledávání: '"KC Gatter"'
3
Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha
Autor: Ms, Wiesener, Turley H, We, Allen, Willam C, Ku, Eckardt, Kl, Talks, Sm, Wood, Kc, Gatter, Al, Harris, Cw, Pugh, Peter Ratcliffe, Ph, Maxwell
Publikováno v: Europe PubMed Central
Hypoxia results in adaptive changes in the transcription of a range of genes including erythropoietin. An important mediator is hypoxia-inducible factor-1 (HIF-1), a DNA binding complex shown to contain at least two basic helix-loop-helix PAS-domain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7eecf9de16704287ec59f734b84d0c2f
https://pubmed.ncbi.nlm.nih.gov/9746763
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4
Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms
Autor: Sb, Fox, Fawcett J, Dg, Jackson, Collins I, Kc, Gatter, Al, Harris, Gearing A, Dl, Simmons
Publikováno v: Europe PubMed Central
At least 20 different isoforms of the human CD44 lymphocyte-homing receptor/hyaluronan receptor have been described to date that arise from the differential splicing of up to 10 alternative exons (termed v1-v10) encoding the membrane-proximal extrace
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::556f0ba528d99d720c6cdc683d0c8a81
https://pubmed.ncbi.nlm.nih.gov/7519124
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7
Loss of transporter in antigen processing 1 transport protein and major histocompatibility complex class I molecules in metastatic versus primary breast cancer
Autor: Kaklamanis L, Russell Leek, Koukourakis M, Kc, Gatter, Al, Harris
Publikováno v: Scopus-Elsevier
Europe PubMed Central
We studied by immunohistochemistry the HLA-allelic, beta 2-microglobulin, and TAP-1 expression in primary breast carcinomas and related lymph node metastases. Thirty-three of the primary tumors and 44% of the lymph node metastases had a complete HLA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0ef0b4ce327d508f383dfb1a515f8c1e
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028789344&partnerID=MN8TOARS
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9
Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer
Autor: Russell Leek, Kl, Talks, Pezzella F, Turley H, Campo L, Ns, Brown, Bicknell R, Taylor M, Kc, Gatter, Al, Harris
Publikováno v: Web of Science
Europe PubMed Central
Tumor-associated macrophages (TAMs) produce angiogenic factors and in breast cancer are associated with high vascular grade and poor survival. TAMs preferentially migrate to hypoxic areas within tumors and strongly express hypoxia-inducible factor (H
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::041f92cbcdac6d4dff2f952d32c45471
https://publons.com/wos-op/publon/34372814/
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