Zobrazeno 1 - 10
of 304
pro vyhledávání: '"KB McCredie"'
Autor:
EH Estey, R Kurzrock, HM Kantarjian, SM O'Brien, KB McCredie, M Beran, C Koller, MJ Keating, C Hirsch-Ginsberg, YO Huh
Publikováno v:
Blood. 79:882-887
We administered one course of 2-chlorodeoxyadenosine (2CdA) at 4 mg/m2 daily for 7 days by continuous intravenous infusion to 46 patients with hairy cell leukemia. Complete remissions occurred in 36 patients (78%; 95% confidence limits, 63% to 89%),
Autor:
HM Kantarjian, B Barlogie, M Pershouse, D Swartzendruber, MJ Keating, KB McCredie, EJ Freireich
Publikováno v:
Blood. 66:39-46
In an effort to develop a new tumor marker suitable for flow cytometric analysis, we examined the value of double-stranded ribonucleic acid (ds- RNA) measurements using propidium iodide after DN'ase treatment. Cellular ds-RNA content was evaluated bo
Publikováno v:
Blood. 65:1071-1078
Twenty-six patients with inv(16)(p13q22) or del(16)(q22) in association with acute myelomonocytic leukemia (AMML-M4, FAB classification), and abnormal marrow eosinophils have been treated at this institute. Initial bone marrow eosinophilia (greater t
Publikováno v:
Blood. 48:795-807
Previous classification in vitro of adult acute leukemia incorporating morphology has been complex and difficult to understand. We have devised a simplified classification based solely on leuekemic proliferation in vitro. Seventy-six patients with ad
Publikováno v:
Blood. 69:1280-1288
Fifty-one patients with previously untreated or minimally treated chronic myelogenous leukemia in chronic phase received human alpha interferon 3 to 9 X 10(6) units intramuscularly (IM) daily until complete hematologic remission, then at doses rangin
Publikováno v:
Blood. 62(5)
We investigated the interaction of monocyte/macrophages and autologous T lymphocytes in the methanol extraction residue (MER) of BCG-induced production of granulocyte-macrophage colony-stimulating activity (CSA). Coincubation of monocyte/macrophages
Publikováno v:
Blood. 71(1)
The leukemia from which the human cell line HL-60 was derived was classified in 1976 as acute progranulocytic leukemia (APL), although it was recognized to show a number of atypical features. In the ensuing 10 years, the concept of APL and its integr
Publikováno v:
Blood. 54(6)
Since interferon administration in the treatment of some malignant conditions has been reported to cause leukopenia, we studied the effects of human leukocyte interferon preparation (HLIF) on myelopoiesis in vitro. The continual presence of HLIF in s
Publikováno v:
Blood. 63(3)
Tumor burden in adult patients with acute leukemia is assessed using the percentage of blast cells in the bone marrow or blood. It is clear, however, that not all blast cells are leukemic cells, especially during rapid marrow regeneration. Similarly,
Publikováno v:
Blood. 60(2)
AMSA was evaluated in the treatment of 109 adults with previously treated acute leukemia. Of the 102 evaluable patients, 82 had AML, 17 ALL, and 3 CML in blastic phase. A number of different dose schedules of AMSA were explored, and we conclude that