Zobrazeno 1 - 10
of 192
pro vyhledávání: '"KAZUTOMO INOUE"'
Autor:
Masatoshi Inden, Dohoon Kim, Yuanjin Gu, Yoshihisa Kitamura, Jun-ichi Kondo, Daiju Tsuchiya, Takashi Taniguchi, Shun Shimohama, Akinori Akaike, Shoichiro Sumi, Kazutomo Inoue
Publikováno v:
Journal of Pharmacological Sciences, Vol 96, Iss 1, Pp 53-64 (2004)
Embryonic stem (ES) cells have many of the characteristics of an optimal cell source for cell-replacement therapy. Although the usefulness of the in vitro generation of dopamine (DA)-neural precursors from ES cells has been widely discussed, function
Externí odkaz:
https://doaj.org/article/1965c6f15ed049679c6154dcd79f0a23
Autor:
Goichi Yanai, Takashi Hayashi, Qi Zhi, Kai-Chiang Yang, Yasumasa Shirouzu, Takashi Shimabukuro, Akihito Hiura, Kazutomo Inoue, Shoichiro Sumi
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64499 (2013)
Islet transplantation is a minimally invasive treatment for severe diabetes. However, it often requires multiple donors to accomplish insulin-independence and the long-term results are not yet satisfying. Therefore, novel ways to overcome these probl
Externí odkaz:
https://doaj.org/article/9120ab3ec79c41cc87e54778fdedc7f3
Autor:
Zhi Qi, Chizuru Yamamoto, Naomi Imori, Ayano Kinukawa, Kai-Chiang Yang, Goichi Yanai, Etsuko Ikenoue, Yanna Shen, Yasumasa Shirouzu, Akihito Hiura, Kazutomo Inoue, Shoichiro Sumi M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Islet transplantation has shown great success in the treatment of type 1 diabetes since the Edmonton protocol was established. However, it still has two major problems to overcome: the lack of organ donors and the side effects of immunosuppression. E
Externí odkaz:
https://doaj.org/article/c8ec3c77ca7b4471aa9275326d711e97
Autor:
Tomonori Sakurai, Akira Satake, Natsuki Nagata, Yuanjun Gu, Akihito Hiura, Kim Doo-Hoon, Hiroshi Hori, Yasuhiko Tabata, Shoichiro Sumi, Kazutomo Inoue M.D., P.H.D.
Publikováno v:
Cell Transplantation, Vol 12 (2003)
The transplantation of a bioartificial pancreas has been regarded as a potential method for successful islet transplantation without any immunosuppressive agents. The subcutaneous site is a very attractive site for transplantation of a bioartificial
Externí odkaz:
https://doaj.org/article/dc436d3719a04261a030040ebe8f2d22
Autor:
Natsuki Nagata, Yuanjun Gu, Hiroshi Hori, A. N. Balamurugan, Maki Touma, Yoshiyuki Kawakami, Wenjing Wang, Tomomi T. Baba, Akira Satake, Masumi Nozawa, Yasuhiko Tabata, Kazutomo Inoue M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 10 (2001)
Islet isolation involves enzymatic digestion of the interstitial matrix and mechanical disruption of the tissue. It is possible that a fundamental change of islet biology resulting from the loss of critical factors required for islet function or surv
Externí odkaz:
https://doaj.org/article/af9ed5bf84d74e81b614e9582623dc3b
Publikováno v:
Cell Transplantation, Vol 10 (2001)
Subcutaneous islet transplantation has become an attractive modality. With development of tissue-engineering techniques, it is possible to rectify the disadvantage of poor blood supply in the subcutaneous site by reconstruction of the capillary netwo
Externí odkaz:
https://doaj.org/article/67d8d71e130a45d48dba4890e12a114e
Autor:
Wenjing Wang, Yuanjun Gu, Masaaki Miyamoto, Hiroshi Hori, Natsuki Nagata, A. N. Balamurugan, Maki Touma, Tomonori Sakurai, Kazutomo Inoue M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 10 (2001)
Microencapsulation of pancreatic islets represents a potentially effective method to prevent graft rejection in allotransplantation or xenotransplantation without the need of immunosuppression. Adequate insulin secretion and glucose responsiveness of
Externí odkaz:
https://doaj.org/article/576cf42b4de7427b92a8898494475315
Autor:
Yuanjun Gu, Yasuhiko Tabata, Yoshiyuki Kawakami, Appakaalai N. Balamurugan, Hiroshi Hori, Natsuki Nagata, Akira Satake, Wanxing Cui, Meirigeng Qi, Yoko Misawa, Maki Toma, Masaaki Miyamoto, Masumi Nozawa, Kazutomo Inoue M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 10 (2001)
The subcutaneous space is a potential site for clinical islet transplantation. Even though there are several advantages, poor blood supply at this site mainly causes failure of islet survival. In this study, angiogenesis was induced in advance at the
Externí odkaz:
https://doaj.org/article/233d2353825b4e2bb95a0c28acbde642
Autor:
Baoyou Xu, Yuanjun Gu, Masaaki Miyamoto, A. N. Balamurugan, Wanxing Cui, Masayuki Imamura, Hiroo Iwata, Kazutomo Inoue M.D.
Publikováno v:
Cell Transplantation, Vol 10 (2001)
In a previous experiment, we demonstrated the anticomplementary efficacy of poly(stryrene sulfonic acid) (PSSa) and poly(2-acrylamido-2-methyl propane sulfonic acid) (PAMPS). The aim of this study was to examine their influence on the function of pan
Externí odkaz:
https://doaj.org/article/8d54746cac554232a35f8742d9cbcf30
Autor:
Hiroshi Hori, Yuan Jun Gu, Natsuki Nagata, Appakaalai N. Balamurugan, Akira Satake, Yoshihiko Morimoto, Wen Jing Wang, Yuko Misawa, Yuka Nozawa, Tomoko Nembai, Masaaki Miyamoto, Masumi Nozawa, Kazutomo Inoue M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 10 (2001)
Porcine endocrine cells were isolated from pancreas of 6-month-old pigs by two-step enzymatic digestion procedures. They were separated by the density gradient (isopycnic) centrifugation method using Histopaque-1077. Isolated cells were cultured and
Externí odkaz:
https://doaj.org/article/d7223c64913449c29841dda3a9260a2c