Zobrazeno 1 - 10
of 49
pro vyhledávání: '"KAZUMASA SEKIHARA"'
Autor:
Kazumasa Sekihara, Hidetomo Himuro, Soji Toda, Nao Saito, Ryoichi Hirayama, Nobuyasu Suganuma, Tetsuro Sasada, Daisuke Hoshino
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1286 (2024)
Anaplastic thyroid cancer (ATC) is a rare but highly aggressive malignancy characterized by advanced disease at diagnosis and a poor prognosis. Despite multimodal therapeutic approaches that include surgery, radiotherapy, and chemotherapy, an optimal
Externí odkaz:
https://doaj.org/article/cc74b5db50f14f1b96ed3b70cf208218
Autor:
Kazumasa Sekihara, Hidetomo Himuro, Nao Saito, Yukihide Ota, Taku Kouro, Yohsuke Kusano, Shinichi Minohara, Ryoichi Hirayama, Hiroyuki Katoh, Tetsuro Sasada, Daisuke Hoshino
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Cervical cancer is the second most common cancer in women and causes more than 250,000 deaths worldwide. Among these, the incidence of cervical adenocarcinomas is increasing. Cervical adenocarcinoma is not only difficult to detect
Externí odkaz:
https://doaj.org/article/ee96c18efec44aceaa33c82678ae581d
Autor:
HIROTAKA NAKAYAMA, NAO SAITO, RIKA KASAJIMA, NOBUYASU SUGANUMA, YASUSHI RINO, KATSUHIKO MASUDO, HARUHIKO YAMAZAKI, SOJI TODA, KAZUMASA SEKIHARA, HIROYUKI IWASAKI, DAISUKE HOSHINO
Publikováno v:
Anticancer Research. 43:1073-1077
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99c1bf017f80211b3020e14fca58eda8
https://doi.org/10.21873/anticanres.16252
https://doi.org/10.21873/anticanres.16252
Autor:
HARUKA YOSHII, KAZUMASA SEKIHARA, YUKA IDETA, SHINTARO NAKAJIMA, IKUMA KATO, MAKIKO OKUBO-SATO, KEI SUGIURA, KENJI MITSUDO, MITOMU KIOI
Publikováno v:
Anticancer Research. 42:3815-3823
SIRT6 is one of seven human sirtuin genes and is known to act as an onco-suppressor gene in colorectal and ovarian cancers, although it is up-regulated in other cancers. Thus, SIRT6 is considered performing both tumor-suppressing and promoting roles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ab9bb4335b432ce0c17a2b75c2061a
https://doi.org/10.21873/anticanres.15872
https://doi.org/10.21873/anticanres.15872
Autor:
Michael Andreeff, Marina Konopleva, Yoshihide Hayashizaki, Takashi Miida, Isao Nagaoka, Hajime Arai, Yasunari Yamanaka, Hiromichi Matsushita, Mamoru Igarashi, Saiko Kazuno, Numsen Hail, Jo Ishizawa, Vivian Ruvolo, Masato Shikami, Kaoru Mogushi, Kazuho Ikeo, Norikazu Monma, Kazumasa Sekihara, Kaori Saitoh, Shinichi Yamamoto, Yoko Tabe
Co-culture with MSC-derived BM-adipocytes inhibits spontaneous apoptosis of primary AMoL cells (S1); Co-culture with BM adipocytes activates p38MAPK cascade and protein folding in AMoL cells (S2); Network of proteins involved in the effects of BM-adi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f2f5289e1f5cb63ebb951f4cdd3862
https://doi.org/10.1158/0008-5472.22416872.v1
https://doi.org/10.1158/0008-5472.22416872.v1
Autor:
Michael Andreeff, Marina Konopleva, Yoshihide Hayashizaki, Takashi Miida, Isao Nagaoka, Hajime Arai, Yasunari Yamanaka, Hiromichi Matsushita, Mamoru Igarashi, Saiko Kazuno, Numsen Hail, Jo Ishizawa, Vivian Ruvolo, Masato Shikami, Kaoru Mogushi, Kazuho Ikeo, Norikazu Monma, Kazumasa Sekihara, Kaori Saitoh, Shinichi Yamamoto, Yoko Tabe
Leukemia cells in the bone marrow must meet the biochemical demands of increased cell proliferation and also survive by continually adapting to fluctuations in nutrient and oxygen availability. Thus, targeting metabolic abnormalities in leukemia cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635a25205630034e552b3c4be383282b
https://doi.org/10.1158/0008-5472.c.6509675
https://doi.org/10.1158/0008-5472.c.6509675
Autor:
Michael Andreeff, Marina Konopleva, Yoshihide Hayashizaki, Takashi Miida, Isao Nagaoka, Hajime Arai, Yasunari Yamanaka, Hiromichi Matsushita, Mamoru Igarashi, Saiko Kazuno, Numsen Hail, Jo Ishizawa, Vivian Ruvolo, Masato Shikami, Kaoru Mogushi, Kazuho Ikeo, Norikazu Monma, Kazumasa Sekihara, Kaori Saitoh, Shinichi Yamamoto, Yoko Tabe
Clinical characteristics of AMoL patients (S1); Quantitative expression of metabolites in U937 cells after BM-adipocyte co-culture and etomoxir treatment (S2); Genes whose expression was altered in U937 cells co-cultured with MSCs or BM-adipocytes an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64b63c190e79a2b216f3a2c92d4cac2
https://doi.org/10.1158/0008-5472.22416869
https://doi.org/10.1158/0008-5472.22416869
Autor:
Kazumasa Sekihara, Kaori Saitoh, Haeun Yang, Haruki Kawashima, Saiko Kazuno, Mika Kikkawa, Hajime Arai, Takashi Miida, Nobuhiro Hayashi, Francois Niyonsaba, Keisuke Sasai, Yoko Tabe
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199117 (2018)
The effects of the high-dose ionizing radiation used in radiotherapy have been thoroughly demonstrated in vitro and in vivo. However, the effects of low-dose ionizing radiation (LDIR) such as computed tomography-guided biopsies and X-ray fluoroscopy
Externí odkaz:
https://doaj.org/article/7253aa4c1e3341adba5ef5981c714c8e
Autor:
Kazumasa Sekihara, Kaori Saitoh, Haeun Yang, Haruki Kawashima, Saiko Kazuno, Mika Kikkawa, Hajime Arai, Takashi Miida, Nobuhiro Hayashi, Francois Niyonsaba, Keisuke Sasai, Yoko Tabe
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205581 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0199117.].
Externí odkaz:
https://doaj.org/article/712a4efd8ff941339c99807ef0a153cf
Autor:
Yoko Tabe, Kensuke Kojima, Shinichi Yamamoto, Kazumasa Sekihara, Hiromichi Matsushita, Richard Eric Davis, Zhiqiang Wang, Wencai Ma, Jo Ishizawa, Saiko Kazuno, Michael Kauffman, Sharon Shacham, Tsutomu Fujimura, Takashi Ueno, Takashi Miida, Michael Andreeff
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137210 (2015)
Mantle cell lymphoma (MCL) is an aggressive B-cell lymphoma characterized by the aberrant expression of several growth-regulating, oncogenic effectors. Exportin 1 (XPO1) mediates the nucleocytoplasmic transport of numerous molecules including oncogen
Externí odkaz:
https://doaj.org/article/ffb823f8503d4ea8842e83150d207de8