Zobrazeno 1 - 10
of 215
pro vyhledávání: '"KAZUKI SASAKI"'
Autor:
Yoshihiro Sakano, Takehiro Noda, Shogo Kobayashi, Hiroshi Akasaka, Kazuya Kato, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hidenori Takahashi, Tadafumi Asaoka, Junzo Shimizu, Hiromi Rakugi, Yuichiro Doki, Hidetoshi Eguchi
Publikováno v:
Annals of Gastroenterological Surgery, Vol 8, Iss 3, Pp 498-506 (2024)
Abstract Aim The number of elderly patients with liver cancer is increasing with the aging society. The Geriatric Prognostic Scoring System is useful in predicting the postoperative prognosis for elderly patients with gastrointestinal cancer. The aim
Externí odkaz:
https://doaj.org/article/ae3984bb114949d281d1c5017bf653c3
Autor:
Weidong Zhang, Ayako Miura, Md Moin Abu Saleh, Koichiro Shimizu, Yuichiro Mita, Ryota Tanida, Satoshi Hirako, Seiji Shioda, Valery Gmyr, Julie Kerr-Conte, Francois Pattou, Chunhuan Jin, Yoshikatsu Kanai, Kazuki Sasaki, Naoto Minamino, Hideyuki Sakoda, Masamitsu Nakazato
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Insulin secretion from pancreatic β cells is regulated by multiple stimuli, including nutrients, hormones, neuronal inputs, and local signalling. Amino acids modulate insulin secretion via amino acid transporters expressed on β cells. The
Externí odkaz:
https://doaj.org/article/13b28fe0aa5b471fb9ba3b62af44728f
Autor:
Hiromichi Sato, Sikun Meng, Tomoaki Hara, Yoshiko Tsuji, Yasuko Arao, Kazuki Sasaki, Shogo Kobayashi, Eric di Luccio, Takaaki Hirotsu, Taroh Satoh, Yuichiro Doki, Hidetoshi Eguchi, Hideshi Ishii
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1342 (2024)
Gastrointestinal cancers, which include a variety of esophageal and colorectal malignancies, present a global health challenge and require effective treatment strategies. In the evolving field of cancer immunotherapy, tissue-resident memory T cells (
Externí odkaz:
https://doaj.org/article/0ee6a72de09048599fcc421fc0d0280f
Autor:
Kazuki Sasaki, Tadafumi Asaoka, Shogo Kobayashi, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Takehiro Noda, Hiroshi Wada, Kunihito Gotoh, Hidenori Takahashi, Noboru Maeda, Yasushi Kimura, Yusuke Ono, Yuichiro Doki, Hidetoshi Eguchi
Publikováno v:
Surgical Case Reports, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Background After orthotopic liver transplantation (OLT), complications such as hepatic artery stenosis, thrombosis, and bleeding are possible. Hepatic artery pseudoaneurysms (HAP) are prone to rupture, rupture hemorrhage, and increased morta
Externí odkaz:
https://doaj.org/article/7bf424aea3494d19b402ff69fee6d9aa
Autor:
Yu Takeda, Daisaku Yamada, Shogo Kobayashi, Kazuki Sasaki, Yoshifumi Iwagami, Yoshito Tomimaru, Takehiro Noda, Hidenori Takahashi, Tadafumi Asaoka, Junzo Shimizu, Yuichiro Doki, Hidetoshi Eguchi
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0310328 (2024)
Pancreatic ductal adenocarcinoma (PDAC) has a high recurrence rate even after radical resection because of subclinical tumors. To manage them, a reliable biomarker that can indicate the presence of subclinical tumors and predict their chemosensitivit
Externí odkaz:
https://doaj.org/article/856fc2da0f9644439c96e4ac8f1e11c5
Autor:
Takeshi Kado, Yoshito Tomimaru, Shogo Kobayashi, Akima Harada, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, Takehiro Noda, Hidenori Takahashi, Shunbun Kita, Iichiro Shimomura, Shigeru Miyagawa, Yuichiro Doki, Hidetoshi Eguchi
Publikováno v:
Journal of Diabetes Research, Vol 2024 (2024)
Islet transplantation (ITx) is an established and safe alternative to pancreas transplantation for type 1 diabetes mellitus (T1DM) patients. However, most ITx recipients lose insulin independence by 3 years after ITx due to early graft loss, such tha
Externí odkaz:
https://doaj.org/article/22b60b28aa9c4ddbb03c1da58aca2796
Autor:
Naoko Sekiguchi, Daisaku Yamada, Shogo Kobayashi, Kazuki Sasaki, Yoshifumi Iwagami, Yoshito Tomimaru, Takehiro Noda, Hidenori Takahashi, Yuichiro Doki, Hidetoshi Eguchi
Publikováno v:
Surgical Case Reports, Vol 9, Iss 1, Pp 1-6 (2023)
Abstract Background Rendu–Osler–Weber disease (Osler disease) is a genetic disease with an autosomal dominant inheritance pattern. It is characterized by widespread telangiectasia in multiple organs. Liver involvement of FNH is relatively common,
Externí odkaz:
https://doaj.org/article/9f17da38bb974ba783a6b6a4b5fe99cc
Autor:
Yoshito Tomimaru, Shogo Kobayashi, Toshinori Ito, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, Takehiro Noda, Hidenori Takahashi, Takashi Kenmochi, Yuichiro Doki, Hidetoshi Eguchi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract In cases after pancreas transplantation (PTx), the pancreas graft might be lost for various reasons, including a pancreatoduodenal graft-related complication or patient death with a functioning graft. Although the causes seem to have distinc
Externí odkaz:
https://doaj.org/article/a11b314ad9394a90ac08cad4a0adb9bc
Autor:
Hirotoshi Takayama, Shogo Kobayashi, Kunihito Gotoh, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Tadafumi Asaoka, Takehiro Noda, Hiroshi Wada, Hidenori Takahashi, Masahiro Tanemura, Yuichiro Doki, Hidetoshi Eguchi
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background SMAD4 is a key mediator of TGFβ signaling and one of the mutated genes in extrahepatic bile duct cancer (eBDC). It has been also reported that SMAD4 has dual functions, in carcinogenesis via silencing and in tumor invasion/metast
Externí odkaz:
https://doaj.org/article/1f4f796cb86d458990abd1c4001f81e2
Autor:
Kazuki Sasaki, Mouhamad Al Moussawy, Khodor I. Abou-Daya, Camila Macedo, Amira Hosni-Ahmed, Silvia Liu, Mariam Juya, Alan F. Zahorchak, Diana M. Metes, Angus W. Thomson, Fadi G. Lakkis, Hossam A. Abdelsamed
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Human activated memory CD8 T cells develop a non-cytotoxic function and influence the fate of autologous naïve CD8 T cells where they acquire an activated/memory state and a hybrid state between naïve and activated memory.
Externí odkaz:
https://doaj.org/article/44b4b05e7ad3482c93e236ebb6b01b84