Zobrazeno 1 - 10
of 205
pro vyhledávání: '"KAZUAKI CHIKAMATSU"'
Autor:
Masayo Hasegawa, Yusuke Amano, Atsushi Kihara, Daisuke Matsubara, Noriyoshi Fukushima, Hideyuki Takahashi, Kazuaki Chikamatsu, Hiroshi Nishino, Yoshiyuki Mori, Naohiro Yoshida, Toshiro Niki
Publikováno v:
Cancer Medicine, Vol 13, Iss 13, Pp n/a-n/a (2024)
Abstract Background Cancer utilizes immunosuppressive mechanisms to create a tumor microenvironment favorable for its progression. The purpose of this study is to histologically characterize the immunological properties of the tumor microenvironment
Externí odkaz:
https://doaj.org/article/8727e4ffaba34f05862e5dcd69c2a7a3
Autor:
Takashi Matsuzuka, Kiyoaki Tsukahara, Seiichi Yoshimoto, Kazuaki Chikamatsu, Akihiro Shiotani, Isao Oze, Yoshiko Murakami, Takeshi Shinozaki, Yuichiro Enoki, Shinichi Ohba, Daisuke Kawakita, Nobuhiro Hanai, Yusuke Koide, Michi Sawabe, Yusuke Nakata, Yujiro Fukuda, Daisuke Nishikawa, Gaku Takano, Takahiro Kimura, Keisuke Oguri, Hitoshi Hirakawa, Yasuhisa Hasegawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-5 (2023)
Abstract This sentinel node (SN) biopsy trial aimed to assess its effectiveness in identifying predictive factors of micrometastases and to determine whether elective neck dissection is necessary in oral squamous cell carcinoma. This retrospective st
Externí odkaz:
https://doaj.org/article/b214fa17c81b46239647ba5b2177ae8c
Autor:
Atsushi Musha, Nobuteru Kubo, Hidemasa Kawamura, Naoko Okano, Hiro Sato, Kohei Okada, Kento Tomizawa, Norichika Ota, Akiko Adachi, Masato Shino, Osamu Nikkuni, Shota Ida, Katsuyuki Shirai, Jun‐ichi Saitoh, Satoshi Yokoo, Kazuaki Chikamatsu, Tatsuya Ohno
Publikováno v:
Cancer Reports, Vol 6, Iss 7, Pp n/a-n/a (2023)
Abstract Background Carbon‐ion radiotherapy (C‐ion RT) is effective for head and neck mucosal melanoma (HN‐MM), including radioresistant mucosal melanoma. Melanoma also responds effectively to immune checkpoint inhibitors (ICIs). Data on the ef
Externí odkaz:
https://doaj.org/article/6cbe1720c61641cab04ce897690fadd6
Autor:
Hideyuki Takahashi, Reika Kawabata-Iwakawa, Shota Ida, Ikko Mito, Hiroe Tada, Kazuaki Chikamatsu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Altered metabolism is an emerging hallmark of cancer. Cancer cells preferentially utilize glycolysis for energy production, termed “aerobic glycolysis.” In this study, we performed a comprehensive analysis of the glycolytic activity in h
Externí odkaz:
https://doaj.org/article/e91c6c8c9ce0479fb7ba42f7cdf46e24
Autor:
Ikko Mito, Hideyuki Takahashi, Reika Kawabata-Iwakawa, Shota Ida, Hiroe Tada, Kazuaki Chikamatsu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Head and neck squamous carcinoma (HNSCC) is highly infiltrated by immune cells, including tumor-infiltrating lymphocytes and myeloid lineage cells. In the tumor microenvironment, tumor cells orchestrate a highly immunosuppressive microenviro
Externí odkaz:
https://doaj.org/article/9a0560d7852a49fca606aa83855221c1
Autor:
Nobuteru Kubo, Makoto Sakai, Hidemasa Kawamura, Takahiro Oike, Yoshiki Kubota, Mai Anakura, Akiko Adachi, Hiro Sato, Atsushi Musha, Naoko Okano, Takuya Kaminuma, Katsuyuki Shirai, Jun-ichi Saitoh, Satoshi Yokoo, Kazuaki Chikamatsu, Tatsuya Ohno
Publikováno v:
Radiation, Vol 1, Iss 3, Pp 183-193 (2021)
Background: Tooth loss reduces quality of life; however, little is known about tooth loss caused by carbon ion radiotherapy (CIRT). Here, we aimed to elucidate the incidence of tooth loss post-CIRT for head and neck tumors and to identify risk-predic
Externí odkaz:
https://doaj.org/article/8d80dbd610404d869aa78f295c02cd0e
Autor:
Shota Ida, Toshiyuki Matsuyama, Kunihiko Ishizawa, Kazuaki Nagashima, Yuka Yoshida, Kazuaki Chikamatsu
Publikováno v:
B-ENT, Vol 17, Iss 3, Pp 196-200 (2021)
Externí odkaz:
https://doaj.org/article/b9320a8f85b34e249f3d952d6da6d063
Autor:
Hiroe Tada, Hideyuki Takahashi, Reika Kawabata-Iwakawa, Yurino Nagata, Miho Uchida, Masato Shino, Shota Ida, Ikko Mito, Toshiyuki Matsuyama, Kazuaki Chikamatsu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract The emergence of immune checkpoint inhibitors (ICIs) has revolutionized the treatment of recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). Biomarkers of the therapeutic efficacy of ICIs have been extensively investiga
Externí odkaz:
https://doaj.org/article/b28b2d63a4804c69a542aee6503715fb
Autor:
Yukihiro Takayasu, Nobuteru Kubo, Masato Shino, Osamu Nikkuni, Shota Ida, Atsushi Musha, Katsumasa Takahashi, Junko Hirato, Katsuyuki Shirai, Jun‐ichi Saitoh, Satoshi Yokoo, Kazuaki Chikamatsu, Tatsuya Ohno, Takashi Nakano, for the Working Group on Head and Neck Tumors
Publikováno v:
Cancer Medicine, Vol 8, Iss 17, Pp 7227-7235 (2019)
Abstract This study aimed to evaluate the efficacy of carbon‐ion radiotherapy in combination with chemotherapy using dacarbazine, nimustine, and vincristine (DAV therapy) in mucosal melanoma. Twenty‐one patients with clinically localized mucosal
Externí odkaz:
https://doaj.org/article/2b6a734a2c474461be926670ea000ca2
Autor:
Atsushi Musha, Nobuteru Kubo, Naoko Okano, Hidemasa Kawamura, Yuhei Miyasaka, Hiro Sato, Yukihiro Takayasu, Kazuaki Chikamatsu, Satoshi Yokoo, Tatsuya Ohno
Publikováno v:
SAGE Open Medical Case Reports, Vol 9 (2021)
A 50-year-old woman with a long history of nasopharyngeal cancer (T2N2M0, squamous cell carcinoma) underwent chemoradiotherapy and surgery. In the past, to prevent tumor recurrence or metastasis, she underwent concurrent chemoradiotherapy or neck dis
Externí odkaz:
https://doaj.org/article/560bc8f4598e4a6c93f01bd34b3cee7b