Zobrazeno 1 - 10
of 126
pro vyhledávání: '"KATSUHIRO MIYAJIMA"'
Autor:
Noriko Suzuki‐Kemuriyama, Akari Abe, Sae Nakane, Kinuko Uno, Shuji Ogawa, Atsushi Watanabe, Ryuhei Sano, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae
Publikováno v:
FEBS Open Bio, Vol 11, Iss 11, Pp 2950-2965 (2021)
Nonalcoholic steatohepatitis (NASH) is often associated with obesity, but some patients develop NASH without obesity. The physiological processes by which nonobese patients develop NASH and cirrhosis have not yet been determined. Here, we analyzed th
Externí odkaz:
https://doaj.org/article/1f1412a381574fb1a0fe5dffddcb28a0
Autor:
Noriko Suzuki-Kemuriyama, Akari Abe, Kiniko Uno, Shuji Ogawa, Atsushi Watanabe, Ryuhei Sano, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Nonalcoholic steatohepatitis (NASH) is a form of liver disease characterized by steatosis, necroinflammation, and fibrosis, resulting in cirrhosis and cancer. Efforts have focused on reducing the intake of trans fatty acids (TFAs)
Externí odkaz:
https://doaj.org/article/6f3573c001754a81b616cac0ff325a12
Autor:
Noriko Suzuki-Kemuriyama, Akari Abe, Kinuko Uno, Shuji Ogawa, Atsushi Watanabe, Ryuhei Sano, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae
Publikováno v:
Lipids in Health and Disease, Vol 21, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/38ec27636a644b1fa234fd727afdd11c
Publikováno v:
Journal of Mathematical and Fundamental Sciences, Vol 50, Iss 3, Pp 332-345 (2018)
Type 2 diabetes mellitus (T2DM) is a degenerative disease that leads to increased inflammation and cyclooxygenase protein production, which causes tissue abnormalities. The aim of this study was to determine the effect of caprine CSN1S2 protein again
Externí odkaz:
https://doaj.org/article/02512a9709a247749bdb63ee71ea73b3
Publikováno v:
International Journal of Endocrinology, Vol 2019 (2019)
Externí odkaz:
https://doaj.org/article/6bf01368687041898e110a19e1f61da9
Autor:
Hikaru Hanyu, Yuki Yokoi, Kiminori Nakamura, Tokiyoshi Ayabe, Keisuke Tanaka, Kinuko Uno, Katsuhiro Miyajima, Yuki Saito, Ken Iwatsuki, Makoto Shimizu, Miki Tadaishi, Kazuo Kobayashi-Hattori
Publikováno v:
Toxins, Vol 12, Iss 10, p 610 (2020)
The different effects of deoxynivalenol (DON) on intestinal barrier and stem cells by its route of exposure remain less known. We explored the toxic effects of DON on intestinal barrier functions and stem cells after DON microinjection (luminal expos
Externí odkaz:
https://doaj.org/article/fc15e2830449414c902f0bd7dafdd403
Autor:
Yasuko Mera, Takashi Kawai, Naoto Ogawa, Naoya Odani, Tomohiko Sasase, Katsuhiro Miyajima, Takeshi Ohta, Makoto Kakutani
Publikováno v:
Journal of Pharmacological Sciences, Vol 129, Iss 3, Pp 169-176 (2015)
JTT-130 was developed as an intestine-specific MTP inhibitor designed to rapidly catabolize after absorption to avoid causing hepatotoxicity due to hepatic MTP inhibition. In previous reports, we have demonstrated that JTT-130 suppresses dietary lipi
Externí odkaz:
https://doaj.org/article/6df01a5e373a4bec90a5262d41be7782
Autor:
Noriko Suzuki-Kemuriyama, Takashi Matsuzaka, Motoko Kuba, Hiroshi Ohno, Song-Iee Han, Yoshinori Takeuchi, Masaaki Isaka, Kazuto Kobayashi, Hitoshi Iwasaki, Shigeru Yatoh, Hiroaki Suzuki, Katsuhiro Miyajima, Dai Nakae, Naoya Yahagi, Yoshimi Nakagawa, Hirohito Sone, Nobuhiro Yamada, Hitoshi Shimano
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157580 (2016)
Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of metabolic syndrome, can progress to steatohepatitis (NASH) and advanced liver damage, such as that from liver cirrhosis and cancer. Recent studies have shown the benefits of cons
Externí odkaz:
https://doaj.org/article/ba72cf7df6544c9194ad881ba3772ffe
Autor:
Yusuke Kemmochi, Katsuhiro Miyajima, Takeshi Ohta, Tomohiko Sasase, Yuzo Yasui, Kaoru Toyoda, Kochi Kakimoto, Toshiyuki Shoda, Akihiro Kakehashi
Publikováno v:
Journal of Diabetes Research, Vol 2014 (2014)
We report uveitis observed in an obese type 2 diabetes rat model, Spontaneously Diabetic Torii Leprfa (SDT fatty) rats aged over 50 weeks. The eyes of SDT fatty rats (16 animals: 7 males and 9 females with 50 or 60 weeks of age) were examined histopa
Externí odkaz:
https://doaj.org/article/e174ce5b50dc4fa6ad51e87550e0d86e
Autor:
Takeshi Ohta, Yoshiaki Katsuda, Katsuhiro Miyajima, Tomohiko Sasase, Shuichi Kimura, Bin Tong, Takahisa Yamada
Publikováno v:
Journal of Diabetes Research, Vol 2014 (2014)
The Spontaneously Diabetic Torii Leprfa (SDT fatty) rat is a novel type 2 diabetic model wherein both male and female rats develop glucose and lipid abnormalities from a young age. In this study, we investigated gender differences in abnormalities an
Externí odkaz:
https://doaj.org/article/1b6e387d709a4a8a9fa9bd216be79774