Zobrazeno 1 - 10
of 1 135
pro vyhledávání: '"KATP channel"'
Autor:
Ilka Bauer, Gerald Rimbach, Sönke Cordeiro, Anja Bosy-Westphal, Julian Weghuber, Ignacio R. Ipharraguerre, Kai Lüersen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Plant extracts are increasingly recognized for their potential in modulating (postprandial) blood glucose levels. In this context, root extracts are of particular interest due to their high concentrations and often unique spectrum of plant bioactives
Externí odkaz:
https://doaj.org/article/36d2e7da9b85427d8b1a1adc4be46d09
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background: Developmental and epileptic encephalopathies (DEEs) are a group of heterogeneous neurodevelopmental diseases characterized mainly by developmental delay/intellectual disability and early-onset epilepsy. Researchers have identified variati
Externí odkaz:
https://doaj.org/article/7bd9df0a61304afd8ded423b486f12d1
Autor:
Shigeki Kitamura, Naoya Murao, Shoko Yokota, Masaru Shimizu, Tomoyuki Ono, Yusuke Seino, Atsushi Suzuki, Yuko Maejima, Kenju Shimomura
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Objective Insulin secretion is regulated by ATP-sensitive potassium (KATP) channels in pancreatic beta-cells. Peroxisome proliferator-activated receptors (PPAR) α ligands are clinically used to treat dyslipidemia. A PPARα ligand, fenofibra
Externí odkaz:
https://doaj.org/article/16b4b294cf154b6cb024b62b129c2711
Autor:
Cheng-Ting Lee, Wen-Hao Tsai, Chien-Ching Chang, Pei-Chun Chen, Cathy Shen-Jang Fann, Hsueh-Kai Chang, Shih-Yao Liu, Mu-Zon Wu, Pao-Chin Chiu, Wen-Ming Hsu, Wei-Shiung Yang, Ling-Ping Lai, Wen-Yu Tsai, Shi-Bing Yang, Pei-Lung Chen
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectiveCongenital hyperinsulinism (CHI) is a group of clinically and genetically heterogeneous disorders characterized by dysregulated insulin secretion. The aim of the study was to elucidate genetic etiologies of Taiwanese children with the most s
Externí odkaz:
https://doaj.org/article/1245d9fc0f6545668f7be7e04ecc5a60
Autor:
Bo Yang, Jia-Lu Yao, Jian-Yi Huo, Yu-Long Feng, William A. Coetzee, Guang-Yin Xu, Hua-Qian Yang
Publikováno v:
Channels, Vol 16, Iss 1, Pp 137-147 (2022)
ATP-sensitive K+ (KATP) channel couples membrane excitability to intracellular energy metabolism. Maintaining KATP channel surface expression is key to normal insulin secretion, blood pressure and cardioprotection. However, the molecular mechanisms r
Externí odkaz:
https://doaj.org/article/eb887e513ba64cf0819a6926e4d62b9e
Autor:
Fatima Maqoud, Nicola Zizzo, Marcella Attimonelli, Antonella Tinelli, Giuseppe Passantino, Marina Antonacci, Girolamo Ranieri, Domenico Tricarico
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: ATP-sensitive-K+ channels (KATP) are involved in diseases, but their role in cancer is poorly described. Pituitary macroadenoma has been observed in Cantu’ syndrome (C.S.), which is associated with the gain-of-function mutations of the
Externí odkaz:
https://doaj.org/article/2d58660cc70b4bcba4f4417daf82deca
Autor:
Arda Kaan ÜNER, Emin KAYMAK, Züleyha DOĞANYİĞİT, Ali Tuğrul AKIN, Kemal Erdem BAŞARAN, Saim ÖZDAMAR, Birkan YAKAN, Enes AKYÜZ
Publikováno v:
Bezmiâlem Science, Vol 10, Iss 2, Pp 168-173 (2022)
Objective:Experimental and clinical studies indicate that cardiovascular system diseases have the highest mortality rate. One of the major factors underlying this high mortality rate is hypoxia. The inward rectifying potassium channel 6.2 (Kir6.2) pl
Externí odkaz:
https://doaj.org/article/57e3d42dfa264918a59f9a48501ee3dd
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