TTFields empowers the anti-glioblastoma activity of CUSP9v3 in vitro

Autor: Cao, Q, Dwucet, A, Kast, R, Hlavac, M, Westhoff, MA, Siegelin, MD, Wirtz, CR, Halatsch, ME, Karpel-Massler, G

Publikováno v: 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCP159 /20220525/

Objective: Drug repurposing is a promising strategy to accelerate the clinical use of therapeutics with anti-neoplastic activity. In this study, we examined whether Tumor Treating Fields (TTFields) enhance the biological effects of the repurposed CUS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99775228ac8597f7d0066165da7d6c70

Identification of Acute Respiratory Distress Syndrome subphenotypes denovo using routine clinical data: a retrospective analysis of ARDS clinical trials

Autor: Osborn J, Israel Silva Maia, Lucas Bulgarelli, Ary Serpa Neto, Kast R, Abhijit Duggal, Rey D, Alexandre Biasi Cavalcanti, Fernando G. Zampieri, Laranjeira Ln, Octávio Deliberato R, Matthew Siuba, Paisani Dm, Van Ark E

RationaleThe acute respiratory distress syndrome (ARDS) is a heterogenous condition, and identification of subphenotypes may help in better risk stratification.ObjectivesIdentify ARDS subphenotypes using new simpler methodology and readily available

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d1edf1c0130bf56a614fd21bfba30e5
https://doi.org/10.1101/2021.07.08.21260102

Risk-sharing policies in the context of the French Flood Prevention Action Programmes

Autor: Erdlenbruch, K., Thoyer, S., Grelot, F., Kast, R., Enjolras, G.

Publikováno v: In Journal of Environmental Management 2009 91(2):363-369

AT 1 inhibition mediated neuroprotection after experimental traumatic brain injury is dependent on neutrophils in male mice.

Autor: Timaru-Kast R; Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131, Mainz, Germany. timaruka@uni-mainz.de., Coronel-Castello SP; Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131, Mainz, Germany.; Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131, Mainz, Germany., Krämer TJ; Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131, Mainz, Germany.; Faculty of Health, University of Witten/Herdecke, Alfred-Herrhausen-Strasse 50, 58455, Witten, Germany., Hugonnet AV; Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131, Mainz, Germany., Schäfer MKE; Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131, Mainz, Germany.; Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131, Mainz, Germany., Sebastiani A; Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131, Mainz, Germany.; Department of Anesthesiology, HELIOS University Hospital Wuppertal, University of Witten/Herdecke, Heusnerstrasse 40, 42283, Wuppertal, Germany., Thal SC; Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131, Mainz, Germany.; Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131, Mainz, Germany.; Department of Anesthesiology, HELIOS University Hospital Wuppertal, University of Witten/Herdecke, Heusnerstrasse 40, 42283, Wuppertal, Germany.

Publikováno v: Scientific reports [Sci Rep] 2023 May 07; Vol. 13 (1), pp. 7413. Date of Electronic Publication: 2023 May 07.

Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinase.

Autor: Kast, R.¹ raimund.kast@bayerhealthcare.com, Schirok, H.², Figueroa-Pérez, S.², Mittendorf, J.², Gnoth, M. J.³, Apeler, H.⁴, Lenz, J.⁴, Franz, J. K.⁴, Knorr, A.¹, Hütter, J.¹, Lobell, M.², Zimmermann, K.¹, Münter, K.¹, Augstein, K. H.¹, Ehmke, H.⁵, Stasch, J. P.¹, Figueroa-Pérez, S (AUTHOR), Hütter, J (AUTHOR), Münter, K (AUTHOR)

Publikováno v: British Journal of Pharmacology. Dec2007, Vol. 152 Issue 7, p1070-1080. 11p. 1 Black and White Photograph, 2 Diagrams, 1 Chart, 6 Graphs.