Zobrazeno 1 - 7
of 7
pro vyhledávání: '"KAREN WAGNER-SOUZA"'
Autor:
VIVIAN M. RUMJANEK, GILMA S. TRINDADE, KAREN WAGNER-SOUZA, MICHELE C. MELETTI-DE-OLIVEIRA, LUIS F. MARQUES-SANTOS, RAQUEL C. MAIA, MÁRCIA A. M. CAPELLA
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 73, Iss 1, Pp 57-69 (2001)
Multidrug resistance to chemotherapy is a major obstacle in the treatment of cancer patients. The best characterised mechanism responsible for multidrug resistance involves the expression of the MDR-1 gene product, P-glycoprotein. However, the resist
Externí odkaz:
https://doaj.org/article/4f1e60d30fdc42f4a6580c471551e705
Ciclosporina A e seus análogos como reversores da resistência a múltiplas drogas em células tumorais
Publikováno v:
Revista Brasileira de Cancerologia, Vol 49, Iss 2 (2003)
A resistência a múltiplas drogas (MDR) é um dos principais obstáculos no tratamento quimioterápico de pacientes com câncer. O processo de resistência é multifatorial, mas o mecanismo mais bem caracterizado é a superexpressão da glicoproteí
Externí odkaz:
https://doaj.org/article/ae4471ab6c1d4c3db212690253543e39
Autor:
Karen Wagner-Souza, Juliana Echevarria-Lima, Marcelo de Miranda Reis, Louise A. Rodrigues, Vivian M. Rumjanek
Publikováno v:
Molecular and Cellular Biochemistry. 252:109-116
A multidrug resistant (MDR) cell line, derived from the human leukaemic cell K562 and selected for its resistance to Vincristine, was shown to be resistant to Thapsigargin (TG). A concentration of 50 nM TG was toxic to K562 cells whereas the MDR cell
Autor:
Maria Helena Ornellas, Eliana Abdelhay, Hilda Rachel Diamond, Vivian M. Rumjanek, Aline Almeida-Oliveira, Bernadete Evangelho Gomes, Luis Fernando Bouzas, Karen Wagner-Souza
Publikováno v:
International journal of molecular medicine. 22(2)
Hematopoietic stem cells (HSC) can be identified by the expression of the CD34 molecule. CD34 + cells are found in bone marrow (BM), umbilical cord blood (UCB) and in mobilized peripheral blood (PB). CD34 + cells express P-glycoprotein (Pgp), a produ
Autor:
Karen, Wagner-Souza, Juliana, Echevarria-Lima, Louise A P, Rodrigues, Marcelo, Reis, Vivian M, Rumjanek
Publikováno v:
Molecular and cellular biochemistry. 252(1-2)
A multidrug resistant (MDR) cell line, derived from the human leukaemic cell K562 and selected for its resistance to Vincristine, was shown to be resistant to Thapsigargin (TG). A concentration of 50 nM TG was toxic to K562 cells whereas the MDR cell
Autor:
R C Maia, M A Capella, G S Trindade, Karen Wagner-Souza, M C de-Oliveira, Vivian M. Rumjanek, Luis Fernando Marques-Santos
Publikováno v:
Anais da Academia Brasileira de Ciências v.73 n.1 2001
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC
Anais da Academia Brasileira de Ciências, Vol 73, Iss 1, Pp 57-69 (2001)
Anais da Academia Brasileira de Ciências, Volume: 73, Issue: 1, Pages: 57-69, Published: MAR 2001
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC
Anais da Academia Brasileira de Ciências, Vol 73, Iss 1, Pp 57-69 (2001)
Anais da Academia Brasileira de Ciências, Volume: 73, Issue: 1, Pages: 57-69, Published: MAR 2001
Multidrug resistance to chemotherapy is a major obstacle in the treatment of cancer patients. The best characterised mechanism responsible for multidrug resistance involves the expression of the MDR-1 gene product, P-glycoprotein. However, the resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d35c5fd93a99e35aa66c9dcefd1a475
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100007
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100007
Publikováno v:
Calcium and Cellular Metabolism ISBN: 9781475795578
A serious problem in cancer chemotherapy involves the generation of multidrug resistance (MDR). This phenomenon represents cross-resistance among a number of drugs, unrelated structurally or functionally, and is one of the major reasons for chemother
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08edb68ba9ea563c2e20c5897c4c9838
https://doi.org/10.1007/978-1-4757-9555-4_10
https://doi.org/10.1007/978-1-4757-9555-4_10