ClinVar: improving access to variant interpretations and supporting evidence

Autor: Jennifer M. Lee, George R. Riley, Chen Chao, Kurt McDaniel, Brandi L. Kattman, Donna Maglott, Zenith Maddipatla, Melissa J. Landrum, Baoshan Gu, Douglas W. Hoffman, Kenneth S. Katz, Garth Brown, J. Bradley Holmes, Mark L. Benson, George Zhou, Karen Karapetyan, Chunlei Liu, Shanmuga Chitipiralla, Michael Ovetsky, Malheiro Aj, Wonhee Jang, Jennifer Hart

Publikováno v: Nucleic Acids Research

ClinVar (https://www.ncbi.nlm.nih.gov/clinvar/) is a freely available, public archive of human genetic variants and interpretations of their significance to disease, maintained at the National Institutes of Health. Interpretations of the clinical sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093ae270a1616614cdabe12da24c0614
http://europepmc.org/articles/PMC5753237

Programmatic conversion of crystal structures into 3D printable files using Jmol

Autor: Robert M. Hanson, Vincent F. Scalfani, Jahred Liddie, Valery Tkachenko, Alexey Pshenichnov, Karen Karapetyan, Jason E. Bara, Antony J. Williams

Publikováno v: Journal of Cheminformatics

Background Three-dimensional (3D) printed crystal structures are useful for chemistry teaching and research. Current manual methods of converting crystal structures into 3D printable files are time-consuming and tedious. To overcome this limitation,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0de4883ef7589321d62a2dc65258c41
https://doi.org/10.1186/s13321-016-0181-z

The Chemical Validation and Standardization Platform (CVSP): large-scale automated validation of chemical structure datasets

Autor: Colin Batchelor, David Sharpe, Antony J. Williams, Valery Tkachenko, Karen Karapetyan

Publikováno v: Journal of Cheminformatics

There are presently hundreds of online databases hosting millions of chemical compounds and associated data. As a result of the number of cheminformatics software tools that can be used to produce the data, subtle differences between the various chem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfde88de83945223711dc691743be633
https://doi.org/10.1186/s13321-015-0072-8

Incorporating Commercial and Private Data into an Open Linked Data Platform for Drug Discovery

Autor: Lee Harland, Antonis Loizou, Stefan Senger, Ivan Mikhailov, Egon Willighagen, Valery Tkachenko, Antony J. Williams, Yrjänä Rankka, Carole Goble, Alasdair J. G. Gray, Karen Karapetyan

Publikováno v: 12th Int. Semantic Web Conference (ISWC 2013)
Maastricht University
Goble, C A, Gray, A J G, Harland, L, Karapetyan, K, Loizou, A, Mikhailov, I, Rankka, Y, Senger, S, Tkachenko, V, Williams, A J & Willighagen, E L 2013, Incorporating Commercial and Private Data into an Open Linked Data Platform for Drug Discovery . in 12th Int. Semantic Web Conference (ISWC 2013) . Springer, Sydney .
Advanced Information Systems Engineering ISBN: 9783642387081
International Semantic Web Conference (2)
The Semantic Web: ISWC 2013, 65-80
ISSUE=1;STARTPAGE=65;ENDPAGE=80;TITLE=The Semantic Web

The Open PHACTS Discovery Platform aims to provide an integrated information space to advance pharmacological research in the area of drug discovery. Effective drug discovery requires comprehensive data coverage, i.e. integrating all available source

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b004279c865ce870bbe67574f5426a
https://research.vu.nl/en/publications/a5224b05-ee00-4298-bbd9-3786f2316a8d