Zobrazeno 1 - 8
of 8
pro vyhledávání: '"KAREN J. AITKEN"'
Autor:
Jia-Xin Jiang, Karen J. Aitken, Chris Sotiropoulos, Tyler Kirwan, Trupti Panchal, Nicole Zhang, Shuye Pu, Shoshana Wodak, Cornelia Tolg, Darius J. Bägli
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/a2bfbf190ebe40aab7867176b3bf8648
Autor:
Jia-Xin, Jiang, Karen J, Aitken, Chris, Sotiropoulos, Chris, Sotiropolous, Tyler, Kirwan, Trupti, Panchal, Nicole, Zhang, Shuye, Pu, Shoshana, Wodak, Cornelia, Tolg, Darius J, Bägli
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69089 (2013)
PLoS ONE
PLoS ONE
Extracellular matrix changes are often crucial inciting events for fibroproliferative disease. Epigenetic changes, specifically DNA methylation, are critical factors underlying differentiated phenotypes. We examined the dependency of matrix-induced f
Autor:
Sanaz, Alali, Karen J, Aitken, Annette, Schröder, Annette, Shröder, Darius J, Bagli, I, Alex Vitkin
Publikováno v:
Journal of biomedical optics. 17(8)
Microstructural remodelling in epithelial layers of various hollow organs, including changes in tissue anisotropy, are known to occur under mechanical distension and during disease processes. In this paper, we analyze how bladder distension alters wa
Autor:
Karen J. Aitken, Gregory Block, Armando Lorenzo, Daniel Herz, Nesrin Sabha, Omar Dessouki, France Fung, Marta Szybowska, Laura Craig, Darius J. Bägli
Excessive wall stretch of distensible hollow organs in cardiovascular and urinary systems can activate matrix metalloproteinases (MMPs), thereby releasing matrix neoepitopes and growth factor ligands, leading to ERK1/2 activation. However, the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531dee228e4aff5d92d2eec7cac2eca6
https://europepmc.org/articles/PMC1698787/
https://europepmc.org/articles/PMC1698787/
Publikováno v:
The Journal of urology. 165(6 Pt 2)
Congenital bladder outlet obstruction from either mechanical or functional causes often results in clinical bladder fibrosis. We tested the hypothesis that early molecular changes relevant to fibrosis occur in response to stretch injury of the bladde
Publikováno v:
Journal of Urology. 177:241-242
Publikováno v:
Journal of Biomedical Optics. 17:109801
Autor:
Kenneth Ting, Karen J Aitken, Frank Penna, Alaleh Najdi Samiei, Martin Sidler, Jia-Xin Jiang, Fadi Ibrahim, Cornelia Tolg, Paul Delgado-Olguin, Norman Rosenblum, Darius J Bägli
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149118 (2016)
UNLABELLED:Host-pathogen interactions can induce epigenetic changes in the host directly, as well as indirectly through secreted factors. Previously, uropathogenic Escherichia coli (UPEC) was shown to increase DNA methyltransferase activity and expre
Externí odkaz:
https://doaj.org/article/ae502ec295864be483d92fde48fba168