Zobrazeno 1 - 10
of 266
pro vyhledávání: '"KAORU YAMADA"'
Autor:
Yoichiro Abe, Natsumi Ikegawa, Keitaro Yoshida, Kyosuke Muramatsu, Satoko Hattori, Kenji Kawai, Minetaka Murakami, Takumi Tanaka, Wakami Goda, Motohito Goto, Taichi Yamamoto, Tadafumi Hashimoto, Kaoru Yamada, Terumasa Shibata, Hidemi Misawa, Masaru Mimura, Kenji F. Tanaka, Tsuyoshi Miyakawa, Takeshi Iwatsubo, Jun-ichi Hata, Takako Niikura, Masato Yasui
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Aquaporin-4 (AQP4) has been suggested to be involved in the pathogenesis of neurodegenerative diseases including Alzheimer’s disease (AD), which may be due to the modulation of neuroinflammation or the impairment of interstitial fluid bulk
Externí odkaz:
https://doaj.org/article/1c8558c64520446089d7b86f40ae3269
Autor:
Tomoko Wakabayashi, Kazuki Yamaguchi, Kentaro Matsui, Toshiharu Sano, Tetsuya Kubota, Tadafumi Hashimoto, Ayako Mano, Kaoru Yamada, Yuko Matsuo, Naoto Kubota, Takashi Kadowaki, Takeshi Iwatsubo
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-18 (2019)
Abstract Background Based on epidemiological and experimental studies, type 2 diabetes mellitus (T2DM), especially insulin resistance that comprises the core mechanism of T2DM, has been recognized as a significant risk factor for Alzheimer’s diseas
Externí odkaz:
https://doaj.org/article/5c9873e539af42909939d09c0139f91b
Autor:
Kaoru Yamada, Takeshi Iwatsubo
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-8 (2018)
Abstract Background α-Synuclein is a presynaptic protein abundant in the cytoplasmic compartment of neurons, whereas its presence in the extracellular space has also been observed under physiological conditions. Extracellular α-synuclein has pathol
Externí odkaz:
https://doaj.org/article/20df47a318b34eb3bce7353354031148
Autor:
Yuki Tanaka, Kaoru Yamada, Kyoko Satake, Itaru Nishida, Matthias Heuberger, Tomoki Kuwahara, Takeshi Iwatsubo
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
The pathological aggregation of tau characterizes a set of neurodegenerative diseases collectively referred to as tauopathies. Recent studies using cellular and animal models have suggested that tau pathology progresses by trans-cellular propagation.
Externí odkaz:
https://doaj.org/article/a05c75f132f34395b9a156504eda7172
Autor:
Kaoru Yamada
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
The pathological aggregation of tau protein is a hallmark of a set of neurodegenerative diseases collectively referred to as tauopathies. Tau aggregates independently in each neuron, but this aggregation can also occur in a non-cell autonomous manner
Externí odkaz:
https://doaj.org/article/f5be75a843004d9b8661f179edd1c694
Autor:
Yoshiki Tsubosaka, Takahisa Murata, Kaoru Yamada, Daisuke Uemura, Masatoshi Hori, Hiroshi Ozaki
Publikováno v:
Journal of Pharmacological Sciences, Vol 113, Iss 3, Pp 208-213 (2010)
Halichlorine is a marine alkaloid isolated from the marine sponge Halichondria okadai KADOTA, and its pathophysiological effect on vascular cells remains unknown. Here, we examined the anti-atherosclerosis activity of halichlorine on endothelial cell
Externí odkaz:
https://doaj.org/article/bfc5aabdc4a749f281ddc6cc77e4178e
Publikováno v:
BioTechniques, Vol 34, Iss 5, Pp 1074-1080 (2003)
Recombinant lentiviral vectors stably transduce both dividing and nondividing cells. Virus pseudotyping with vesicular stomatitis virus envelope G (VSV-G) protein broadens the host range of lentiviral vector and enables vector concentration by ultrac
Externí odkaz:
https://doaj.org/article/77ff9896e246443db4c314b37c097f0a
Autor:
Seido Takae, Ikkei Oyama, Mukyo Abe, Hideo Sugo, Yumari Kusano, Yoichiro Imaoka, Yuka Makino, Arisa Ukai, Yuko Mitsuyama, Chiaki Fujino, Rieka Miyamoto, Manami Yoshimura, Kaoru Yamada, Nao Suzuki
Publikováno v:
International Journal of Clinical Oncology. 28:191-200
The focus on cancer in adolescents and young adults (AYA) has increased in recent years. We participated in an event called AYA week 2021 as part of a research project of the Ministry of Health, Labour and Welfare (MHLW) and conducted a fact-finding
Autor:
Nanaka Yamaguchi-Takegami, Akiko Takahashi, Jun Mitsui, Yusuke Sugiyama, Ayaka Chikada, Porto, Kristine Joyce L., Naoki Takegami, Kaori Sakuishi, Hiroyuki Ishiura, Kaoru Yamada, Jun Shimizu, Shoji Tsuji, Tatsushi Toda
Publikováno v:
Internal Medicine; 2024, Vol. 63 Issue 6, p861-865, 5p
Autor:
Mitsunori Fukuda, Taro Saito, Anni Huo, Shigeo Murayama, Takeshi Iwatsubo, Mineko Tomomura, Ran Wei, Shikito Ikeda, Wataru Araki, Masato Hasegawa, Yutaka Sato, Kanae Ando, Tetsuya Takano, Kaoru Yamada, Keisuke Komaki, Shin-ichi Hisanaga, Aoi Fukuchi, Fuyuki Kametani, Akiko Asada
Publikováno v:
The Journal of Biochemistry. 170:729-738
Lemur tail kinase 1 (LMTK1), previously called apoptosis-associated tyrosine kinase (AATYK), is an endosomal Ser/Thr kinase. We recently reported that LMTK1 regulates axon outgrowth, dendrite arborization and spine formation via Rab11-mediated vesicl