Zobrazeno 1 - 10
of 66
pro vyhledávání: '"K.W. Marvin"'
Autor:
R. Stewart Gilmour, K.W. Marvin, Elicia B.E Berry, R.L. Eykholt, Murray D. Mitchell, Rachel J. A. Helliwell
Publikováno v:
Molecular Pharmacology. 64:1586-1590
Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors that are involved in lipid metabolism, differentiation, proliferation, cell death, and inflammation. Three subtypes have been identified: PPAR-alpha, -delta, and -g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4a86ff71c7844539874ce3d150a0cf
https://doi.org/10.1124/mol.64.6.1586
https://doi.org/10.1124/mol.64.6.1586
Publikováno v:
American Journal of Obstetrics and Gynecology. 187:728-734
Objective: Our objective was to identify the novel or differential expression of growth or development associated genes in the human gestational membranes that might play roles in pregnancy or in term or preterm parturition. Study Design: Complementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8fc15a0a8a797e16ba1180c5e13daad
https://doi.org/10.1067/mob.2002.126286
https://doi.org/10.1067/mob.2002.126286
Publikováno v:
Molecular Human Reproduction. 8:399-408
Inflammatory processes are implicated in preterm labour (PTL). To identify potential novel markers for PTL, we have used commercial cDNA arrays to generate profiles of differential expression of inflammation-associated genes in gestational membranes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f673b6a84aa1337a55ca9bfb67d6ce
https://doi.org/10.1093/molehr/8.4.399
https://doi.org/10.1093/molehr/8.4.399
UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term
Autor:
Malcolm D. Tingle, James W. Paxton, Natalie A. Ganley, Abby C. Collier, Jeffrey A. Keelan, Murray D. Mitchell, Marion Blumenstein, K.W. Marvin
Publikováno v:
ResearcherID
The activity, expression and localization of the UDP-glucuronosyltransferases (UGTs) were investigated in human placenta at term. UGT activity (measured with the substrate 4-methylumbelliferone (4-MU)) was observed in all 25 placentas sampled and max
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c9764ddad465542f672a9460d3287a
https://doi.org/10.1016/s0006-2952(01)00890-5
https://doi.org/10.1016/s0006-2952(01)00890-5
Autor:
Elicia B. E. Berry, K.W. Marvin, R. Stewart Gilmour, Bianca E. Nijmeijer, Jeffrey A. Keelan, Murray D. Mitchell, Rachel J. A. Helliwell, Timothy A. Sato
Publikováno v:
Prostaglandins & Other Lipid Mediators. 66:265-282
Apoptosis at the site of rupture has been proposed to play a role in premature rupture of the fetal membranes, a condition associated with increased risk of neonatal sepsis and preterm birth. We investigated the ability of peroxisome proliferator-act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1609a0fcd8e6346ddd268afaaf7bcbf
https://doi.org/10.1016/s0090-6980(01)00164-2
https://doi.org/10.1016/s0090-6980(01)00164-2
Publikováno v:
American Journal of Reproductive Immunology. 46:413-419
Problem: The pro-inflammatory cytokine interleukin (IL)-1 beta has been shown to stimulate the production of prostaglandins (PG) in gestational tissues. Increased PG synthesis is considered a key step in the initiation of labor both at term and prete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7f2f62899e59aa9745c0ae354863da7
https://doi.org/10.1034/j.1600-0897.2001.d01-33.x
https://doi.org/10.1034/j.1600-0897.2001.d01-33.x
Publikováno v:
ResearcherID
Prostaglandin-H-synthase-1 (PGHS-1), while constitutively expressed in most tissues, increases in abundance in human gestational membranes at term. This suggests that PGHS-1 may be up-regulated in preparation for labor, and thus might be a key determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d48f3ef8734a88062890d122885f881
https://doi.org/10.1016/s0090-6980(00)00102-7
https://doi.org/10.1016/s0090-6980(00)00102-7
Publikováno v:
Placenta. 21:789-798
Tumour necrosis factor (TNF)-alpha-stimulated prostaglandin (PG) E(2)biosynthesis by amnion-derived AV3 cells is accompanied by increased prostaglandin H synthase (PGHS)-2 mRNA expression. PGHS-1 mRNA expression is unchanged. PGHS-2 promoter-reporter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef54b4471a5401909926ec764a1a1d6
https://doi.org/10.1053/plac.2000.0576
https://doi.org/10.1053/plac.2000.0576
Publikováno v:
Molecular Human Reproduction. 6:771-778
Prostaglandin H synthase (PGHS)-2 promoter fragments (-528 to +9 bp and 5' unidirectional deletions thereof) were cloned upstream of the chloramphenicol acetyl-transferase (CAT) reporter gene. These were transfected into amnion-derived AV3 cells. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b952de68605e0fd8d27d05a722b6d66b
https://doi.org/10.1093/molehr/6.9.771
https://doi.org/10.1093/molehr/6.9.771
Publikováno v:
ResearcherID
To test the hypothesis that amnion cytokine production might be regulated by prostanoids.Amnion-derived WISH cells were treated with a range of prostanoids and their effects on production of interleukin (IL)-6 and IL-8 were determined by enzyme-linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab57744da695f217dc86d05f6a22ca6
https://doi.org/10.1177/107155760000700106
https://doi.org/10.1177/107155760000700106