Zobrazeno 1 - 10
of 336
pro vyhledávání: '"K.V. Toyka"'
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 1, Pp 191-199 (2009)
Autoantibodies to the synaptic protein amphiphysin play a crucial pathogenic role in paraneoplastic stiff-person syndrome. Impairment of GABAergic inhibition is the presumed pathophysiological mechanism by which these autoantibodies become pathogenic
Externí odkaz:
https://doaj.org/article/58eee0933bbb4b2a95e532b7dbd428ca
Autor:
V. Andresen, U. Bingel, T. Brandt, F. Brassel, C. Daniels, G. Deuschl, H.-C. Diener, H.-H. Eckstein, C.E. Elger, I. Eyüpoglu, S. Faissner, M. Forsting, R. Gold, D. Heuß, H.C. Hopf, M. Jeup, B. Jordan, O. Kastrup, M. Klein, J. Kleine-Borgmann, S. Kovac, J.B. Kuramatsu, P. Layer, V. Limmroth, W. Nacimiento, G. Nickenig, H.-W. Pfister, J. Schipper, C. Schneider-Gold, M. Scholz, C.-M. Sommer, M. Strupp, U. Sure, K.V. Toyka, K.H. von Schassen, C.-W. Wallesch, S. Zierz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d6ad2d91f166f1d1ea53e8fa0a5960f
https://doi.org/10.1016/b978-3-437-23844-4.00030-5
https://doi.org/10.1016/b978-3-437-23844-4.00030-5
Autor:
Robert L. Rodnitzky
Publikováno v:
Muscle & Nerve. 12:427-427
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87a1d36ab5e18f607e7fcbd336f65395
https://doi.org/10.1002/mus.880120515
https://doi.org/10.1002/mus.880120515
Autor:
K.V. Toyka, R. Hohlfeld
Publikováno v:
Der Nervenarzt. 82:1026-1035
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe95baaa09de6624b1eb4495aa35317e
https://doi.org/10.1007/s00115-011-3264-0
https://doi.org/10.1007/s00115-011-3264-0
Publikováno v:
Der Nervenarzt. 81:1218-1225
Symptomatic treatment of amyotrophic lateral sclerosis (ALS) is relevant in preventing complications and improving quality of life as long as curative therapies are still out of sight. About one third of ALS patients show disabling problems associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca3b879218a77f901c467bf9fd4ba10c
https://doi.org/10.1007/s00115-010-3008-6
https://doi.org/10.1007/s00115-010-3008-6
Autor:
Djeda Belharazem, Peter Rieckmann, Kiefer R, Wen-Yu Chuang, Wilfried Nix, Philipp Ströbel, Masayoshi Inoue, Erdwine Klinker, Andreas Opitz, Hans Konrad Müller-Hermelink, Berthold Schalke, Alexander Marx, Ralf Gold, K.V. Toyka, Tseng-tong Kuo
Publikováno v:
Genes & Immunity. 10:667-672
Protein tyrosine phosphatase, non-receptor type 22 (PTPN22) inhibits T-cell activation and interleukin-2 (IL-2) production. The PTPN22(gain-of-function)+1858T(+) genotypes predispose to multiple autoimmune diseases, including early-onset (non-thymoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f590f9a5da1f5d845b39db6522ad4b6b
https://doi.org/10.1038/gene.2009.64
https://doi.org/10.1038/gene.2009.64
Publikováno v:
Clinical and Experimental Immunology. 157:332-342
Summary Plasmacytoid dendritic cells (pDCs) are of crucial importance in immune regulation and response to microbial factors. In multiple sclerosis (MS), pDCs from peripheral blood showed an immature phenotype, but its role in susceptibility to MS is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6404e22300d57dc8391bccbf5075ebe1
https://doi.org/10.1111/j.1365-2249.2009.03964.x
https://doi.org/10.1111/j.1365-2249.2009.03964.x
Autor:
Ernst-Wilhelm Radue, K.V. Toyka, Franz Fazekas, M. Sailer, Martin Bendszus, Peter Rieckmann, Heinz Wiendl, Ludwig Kappos, Achim Gass
Publikováno v:
RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 180:994-1001
PURPOSE: Magnetic resonance imaging (MRI) has become a valuable tool for diagnosing and monitoring multiple sclerosis (MS). The high sensitivity for the detection of hyperintense lesions in T 2-weighted scans contributes substantially to diagnosis. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc8628251de325bfdb0ecd80cc23d640
https://doi.org/10.1055/s-2008-1027817
https://doi.org/10.1055/s-2008-1027817