Zobrazeno 1 - 10 of 14 pro vyhledávání: '"K.S. Navya Sree"'
1
Dronedarone HCl–Quercetin Co-Amorphous System: Characterization and RP-HPLC Method Development for Simultaneous Estimation
Autor: Swapnil J. Dengale, Srinivas Mutalik, K.S. Navya Sree, Krishnamurthy Bhat
Publikováno v: Journal of AOAC INTERNATIONAL. 104:1232-1237
Background Dronedarone HCl (DRN) is an anti-arrhythmic drug indicated for atrial fibrillation. DRN has a low solubility of 2 µg/mL and 4% bioavailability, thus it is formulated as a co-amorphous system to enhance its solubility by using quercetin (Q
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71c09f47868b8c86e11a0869ee1162a
https://doi.org/10.1093/jaoacint/qsab024
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3
Considerations for the selection of co-formers in the preparation of co-amorphous formulations
Autor: Athira R. Nair, K.S. Navya Sree, Swapnil J. Dengale, Vullendula Sai Krishna Anand, Krishnamurthy Bhat, Dani Lakshman Yarlagadda
Publikováno v: International journal of pharmaceutics. 602
Co-amorphous drug delivery systems are evolving as a credible alternative to amorphous solid dispersions technology. In Co-amorphous systems (CAMs), a drug is stabilized in amorphous form using small molecular weight compounds called as co-formers. A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc8be5b074df3a34b34f4158dcb97cf
https://pubmed.ncbi.nlm.nih.gov/33915186
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4
Overview of Extensively Employed Polymeric Carriers in Solid Dispersion Technology
Autor: Krishnamurthy Bhat, Swapnil J. Dengale, Vullendula Sai Krishna Anand, K.S. Navya Sree, Athira R. Nair, Yarlagadda Dani Lakshman
Publikováno v: AAPS PharmSciTech
Solid dispersion is the preferred technology to prepare efficacious forms of BCS class-II/IV APIs. To prepare solid dispersions, there exist a wide variety of polymeric carriers with interesting physicochemical and thermochemical characteristics avai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321bbd2bf9add8fcd119c65baf1393c7
https://doi.org/10.1208/s12249-020-01849-z
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5
The Significance of Utilizing In Vitro Transfer Model and Media Selection to Study the Dissolution Performance of Weak Ionizable Bases: Investigation Using Saquinavir as a Model Drug
Autor: Swapnil J. Dengale, Aman Urazov, Geeta K. Hanegave, Mohith Chegireddy, Dani Lakshman, K.S. Navya Sree, Shaila A. Lewis
Publikováno v: AAPS PharmSciTech. 21
This study investigated the dissolution behavior of BCS class II ionizable weak base Saquinavir and its mesylate salt in the multi-compartment transfer setup employing different composition of dissolution media. The dissolution behavior of Saquinavir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b3d11708ec9dbabf7196a1365663ca1
https://doi.org/10.1208/s12249-019-1563-0
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6
The Assessment of pH-Induced Supersaturation and Impact of an Additional Drug on the Solution Phase Behavior of Saquinavir
Autor: V. Sai Krishna Anand, Swapnil J. Dengale, Sujata D. Sakhare, K.S. Navya Sree, Aishwarya Karan, S. G. Vasantharaju, Girish K Pai
Publikováno v: Journal of Pharmaceutical Innovation. 14:305-315
The goal of this study was to investigate the ability of saquinavir to generate the in vivo supersaturation and the impact of the presence of another solute, i.e., ritonavir, on the phase behavior of the former. The phase behavior of saquinavir alone
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc6735400a8a76fa1c85bebeb05466e5
https://doi.org/10.1007/s12247-018-9357-6
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7
The relevance of co-amorphous formulations to develop supersaturated dosage forms: In-vitro, and ex-vivo investigation of Ritonavir-Lopinavir co-amorphous materials
Autor: Sujata D. Sakhare, Swapnil J. Dengale, Athira R. Nair, K. Raghava Varma, Karthik Gourishetti, K.S. Navya Sree, V. Sai Krishna Anand
Publikováno v: European Journal of Pharmaceutical Sciences. 123:124-134
Ritonavir and Lopinavir have previously been demonstrated to decrease the maximum solubility advantage and flux in the presence of each other. The present study investigated the ability of Ritonavir and Lopinavir co-amorphous materials to generate a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56b13d1101a3e0f971dd6f3683d3323
https://doi.org/10.1016/j.ejps.2018.07.046
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8
Investigation of drug-polymer miscibility, biorelevant dissolution, and bioavailability improvement of Dolutegravir-polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer solid dispersions
Autor: Mohith Chegireddy, K.S. Navya Sree, Naveen Kumar, Swapnil J. Dengale, Shaila A. Lewis, Geeta K. Hanegave, Dani Lakshman
Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 142
The aim of the current study was to prepare the efficacious amorphous solid dispersion of poorly water-soluble compound, Dolutegravir. After theoretical and experimental determination of drug-polymer miscibility, polyvinyl caprolactam-polyvinyl aceta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5477662e78c27f2f748e0a3f0452278
https://pubmed.ncbi.nlm.nih.gov/31706016
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9
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10
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