Zobrazeno 1 - 10
of 91
pro vyhledávání: '"K.S. Albert"'
Publikováno v:
Analytical Letters. 18:891-900
A low-resolution method for simultaneous, rapid determination of radiolabeled glyburide and its metabolites in human plasma is described. Plasma samples were extracted with ethyl acetate. Extracts were redissolved in 300 μl of mobile phase, and inje
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 11:561-576
This study was conducted to evaluate the influence of route of administration upon the bioavailability and pharmacokinetics of methylprednisolone sodium succinate. Fourteen healthy adult male volunteers received 40 mg doses of methylprednisolone as t
Publikováno v:
Clinical Pharmacology and Therapeutics. 34:707-710
We evaluated kinetics of ibuprofen and acetaminophen taken concurrently by 20 healthy adults in a randomized crossover design. Steady-state blood levels of ibuprofen and acetaminophen were measured by gas-liquid chromatography and HPLC. There were no
Publikováno v:
The Journal of Clinical Pharmacology. 26:184-190
The pharmacokinetics of ibuprofen and its two major metabolites, the hydroxy and carboxy derivatives, were studied in seven functionally anephric subjects undergoing hemodialysis therapy. Subjects received ibuprofen 800 mg tid for 14 days. Hemodialys
Publikováno v:
The Journal of Clinical Pharmacology. 26:65-70
After administration of a single dose and at steady state, ibuprofen concentrations were measured simultaneously in plasma and synovial fluid obtained from eight patients with rheumatoid arthritis. By seven hours after a dose at steady state, the mea
Autor:
C.E. Wright, Steven R. Cox, Edward J. Antal, K.S. Albert, Vincent J. Capponi, E. L. Harrington
Publikováno v:
Journal of Pharmaceutical Sciences. 74:308-311
Fluoxymesterone was extracted from serum with a liquid-liquid extraction procedure. Serum containing both drug and internal standard, 6 alpha-methylprednisolone, was extracted with methylene chloride. The extract was washed with 0.1 M NaOH and water,
Publikováno v:
Journal of Pharmaceutical Sciences. 71:1259-1263
The relative bioavailability of tolazamide was determined, in healthy male volunteers, from four different tablet formulations manufactured by direct compaction or granulation processes and the results were compared with in vitro disintegration and d
Publikováno v:
American Journal of Health-System Pharmacy. 40:1025-1034
Publikováno v:
Pharmacology. 21:38-42
The relative degree of absorption of methylprednisolone acetate when administered by the rectal and oral routes was studied in 12 normal male subjects. The plasma samples were assayed for methylprednisolone and endogenous hydrocortisone concentration
Publikováno v:
European Journal of Clinical Pharmacology. 22:459-462
The effect of food on the rate and extent of absorption of tolbutamide in diabetic patients was studied by varying the time of drug administration in relation to the ingestion of a standard meal. Serum levels of tolbutamide, insulin and glucose and r