Zobrazeno 1 - 10
of 30
pro vyhledávání: '"K.R. Valetdinova"'
Autor:
A.A. Malakhova, E.V. Grigor'eva, S.V. Pavlova, T.B. Malankhanova, K.R. Valetdinova, Y.V. Vyatkin, E.A. Khabarova, J.A. Rzaev, S.M. Zakian, S.P. Medvedev
Publikováno v:
Stem Cell Research, Vol 48, Iss , Pp 101952- (2020)
ICGi021-A and ICGi022-A iPSC lines were obtained by reprogramming PBMCs of two healthy women of the Siberian population using episomal non-integrating vectors expressing Yamanaka factors. iPSC lines expressed pluripotency markers, had a normal karyot
Externí odkaz:
https://doaj.org/article/9d8dd950a4cd4f2fa1aadd4fa1c189fa
Autor:
V.S. Ovechkina, M.A. Maretina, A.A. Egorova, V.S. Baranov, A.V. Kiselev, S.M. Zakian, K.R. Valetdinova
Publikováno v:
Stem Cell Research, Vol 48, Iss , Pp 101938- (2020)
Spinal muscular atrophy (SMA) is a genetic disease, which characterized by the degeneration of motor neurons in the spinal cord and further striated muscle atrophy. The research of the processes in diseased neurons is complicated due to the impossibi
Externí odkaz:
https://doaj.org/article/bf741271868e47dcbfeb7f849d66b1ca
Autor:
K.R. Valetdinova, M.A. Maretina, Y.V. Vyatkin, M.P. Perepelkina, A.A. Egorova, V.S. Baranov, A.V. Kiselev, P.M. Gershovich, S.M. Zakian
Publikováno v:
Stem Cell Research, Vol 48, Iss , Pp 101941- (2020)
Duchenne muscular dystrophy (DMD) is a severe and rapidly progressive hereditary muscular disease with X-linked recessive inheritance, occurring mainly in males. A complete loss of dystrophin resulted from out-of-frame deletion mutations in the DMD g
Externí odkaz:
https://doaj.org/article/23af4a55003e44e8a54f9ecf0d389056
Autor:
A.A. Malakhova, E.V. Grigor'eva, T.B. Malankhanova, S.V. Pavlova, K.R. Valetdinova, N.Yu. Abramycheva, A.S. Vetchinova, S.N. Illarioshkin, S.M. Zakian
Publikováno v:
Stem Cell Research, Vol 44, Iss , Pp - (2020)
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by CAG repeat expansion in the HTT gene. HD patient-specific induced pluripotent stem cells (iPSCs) represent an excellent model for the disease study. We generated i
Externí odkaz:
https://doaj.org/article/3bd98ba29c1a4e39b94c3a98e499c2c7
Autor:
K.R. Valetdinova, M.A. Maretina, M.L. Kuranova, E.V. Grigor'eva, Y.M. Minina, E.A. Kizilova, A.V. Kiselev, S.P. Medvedev, V.S. Baranov, S.M. Zakian
Publikováno v:
Stem Cell Research, Vol 34, Iss , Pp - (2019)
Spinal muscular atrophy (SMA) is a neuromuscular disease caused by deletion or mutation in SMN1 gene. SMA human induced pluripotent stem cells (iPSCs) represent a useful and valid model for the study of the disorder, as they provide in vitro the targ
Externí odkaz:
https://doaj.org/article/7c9dc979c49c49ab94e6717af9e83b5e
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 1528, p 1528 (2021)
Biomedicines, Vol 9, Iss 1528, p 1528 (2021)
One of the challenges of modern biology and medicine is to visualize biomolecules in their natural environment, in real-time and in a non-invasive fashion, so as to gain insight into their physiological behavior and highlight alterations in pathologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6054c580a9e4e20e8059d50f3a1b89
https://pubmed.ncbi.nlm.nih.gov/34829757
https://pubmed.ncbi.nlm.nih.gov/34829757
Akademický článek
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Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 960, p 960 (2021)
Biomedicines, Vol 9, Iss 960, p 960 (2021)
The development of cell models of human diseases based on induced pluripotent stem cells (iPSCs) and a cell therapy approach based on differentiated iPSC derivatives has provided a powerful stimulus in modern biomedical research development. Moreover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7487a04ab6a7543f522462222d36450
http://europepmc.org/articles/PMC8392144
http://europepmc.org/articles/PMC8392144
Publikováno v:
Biochemistry (Moscow). 84:1074-1084
The CRISPR/Cas technology has a great potential in the treatment of many hereditary diseases. One of the prospective models for the CRISPR/Cas-mediated therapy is spinal muscular atrophy (SMA), a disease caused by deletion of the SMN1 gene that encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4551bfeb3276edfc3563cef058957dfc
https://doi.org/10.1134/s0006297919090104
https://doi.org/10.1134/s0006297919090104
Autor:
A.A. Egorova, P.M. Gershovich, M.P. Perepelkina, K.R. Valetdinova, Suren M. Zakian, A.V. Kiselev, Marianna Maretina, Yuri Vyatkin, Vladislav S Baranov
Publikováno v:
Stem Cell Research, Vol 48, Iss, Pp 101941-(2020)
Duchenne muscular dystrophy (DMD) is a severe and rapidly progressive hereditary muscular disease with X-linked recessive inheritance, occurring mainly in males. A complete loss of dystrophin resulted from out-of-frame deletion mutations in the DMD g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18153dc9df7635bb31aee50684774ef1
http://www.sciencedirect.com/science/article/pii/S1873506120302427
http://www.sciencedirect.com/science/article/pii/S1873506120302427