Výsledky vyhledávání - "K.R. Serafim"

Akademický článek

Systemic injection of an H4 receptor agonist induces a decrease in CREB and pCREB levels in the cerebellar vermis and prefrontal cortex in mice

Autor: C.E.M. Fernandes, K.R. Serafim, A.C.L. Gianlorenço, R. Mattioli

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 52, Iss 5 (2019)

Studies have shown that an injection with the histamine H4 receptor agonist VUF-8430 modulates emotional memory processes. In the present study, the aim was to verify if intraperitoneal (ip) injection of VUF-8430 (500 ng/kg) in mice affects the synth

Externí odkaz: https://doaj.org/article/d6ed2378ca7a4340b179ab2294437491

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Akademický článek

Effect of histamine H1 and H2 receptor antagonists, microinjected into cerebellar vermis, on emotional memory consolidation in mice

Autor: A.C.L. Gianlorenco, K.R. Serafim, A. Canto-de-Souza, R. Mattioli

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 47, Iss 2, Pp 135-143 (2014)

This study investigated the effects of histamine H1 or H2 receptor antagonists on emotional memory consolidation in mice submitted to the elevated plus maze (EPM). The cerebellar vermis of male mice (Swiss albino) was implanted using a cannula guide.

Externí odkaz: https://doaj.org/article/16b380458105437286da667941caa54e

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Akademický článek

Low-dose thioperamide injected into the cerebellar vermis of mice immediately after exposure to the elevated plus-maze impairs their avoidance behavior on re-exposure to the apparatus

Autor: J. Costa Neto, K.R. Serafim, A.C.L. Gianlorenco, R. Mattioli

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 46, Iss 11, Pp 943-948 (2013)

The present study investigated the effect of thioperamide (THIO), an H3 histaminergic receptor antagonist, microinjected into the cerebellar vermis on emotional memory consolidation in male Swiss albino mice re-exposed to the elevated plus-maze (EPM)

Externí odkaz: https://doaj.org/article/446faf628805469593d7aac1ac1a2830

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Akademický článek

H1 but not H2 histamine antagonist receptors mediate anxiety-related behaviors and emotional memory deficit in mice subjected to elevated plus-maze testing

Autor: K.R. Serafim, M.S. Kishi, A. Canto-de-Souza, R. Mattioli

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 46, Iss 5, Pp 440-446 (2013)

This study investigated the role of H1 and H2 receptors in anxiety and the retrieval of emotional memory using a Trial 1/Trial 2 (T1/T2) protocol in an elevated plus-maze (EPM). Tests were performed on 2 consecutive days, designated T1 and T2. Before

Externí odkaz: https://doaj.org/article/fe3b733723f2493d9a8b2ea82a502449

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Akademický článek

L-histidine provokes a state-dependent memory retrieval deficit in mice re-exposed to the elevated plus-maze

Autor: K.R. Serafim, M. Kishi, A. Canto-de-Souza, R. Mattioli

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 43, Iss 1, Pp 100-106 (2010)

The effects of L-histidine (LH) on anxiety and memory retrieval were investigated in adult male Swiss Albino mice (weight 30-35 g) using the elevated plus-maze. The test was performed on two consecutive days: trial 1 (T1) and trial 2 (T2). In T1, mic

Externí odkaz: https://doaj.org/article/1b2fac7c388d4477a723edb8805cca6e

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Systemic injection of an H4 receptor agonist induces a decrease in CREB and pCREB levels in the cerebellar vermis and prefrontal cortex in mice

Autor: Rosana Mattioli, A.C.L. Gianlorenço, K.R. Serafim, C.E.M. Fernandes

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 52, Iss 5 (2019)
Brazilian Journal of Medical and Biological Research v.52 n.5 2019
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230316638c134082e4456dae9d0dd98e
https://doi.org/10.1590/1414-431x20198334

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Intra-vermis H4 receptor agonist impairs performance in anxiety- and fear-mediated models

Autor: C.E.M. Fernandes, Rosana Mattioli, K.R. Serafim, A.C.L. Gianlorenço

Publikováno v: Brain research bulletin. 135

The neural histaminergic system modulates cognitive performance in various animal models. However, little is known about the effects of the H4 histaminergic receptor in the central nervous system. The purpose of this study was to investigate the effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2eddd4f83fd1e415072aec6ed2a21a
https://pubmed.ncbi.nlm.nih.gov/29097243

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Effects of chronic treatment with chlorpheniramine on anxiety and emotional memory in mice

Autor: K.R. Serafim, Rosana Mattioli, Azair Canto-de-Souza, A.C.L. Gianlorenço

Publikováno v: ConScientiae Saúde. 12:345-352

Introduction: H1 receptors mediate actions in brain activity, and antihistamines such as chlorpheniramine (CPA) act as H1 antagonists. Objective: This study investigated the effects of chronic treatment with CPA on anxiety and emotional memory in mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c146442dd80ddce490fa840e3a2c8a28
https://doi.org/10.5585/conssaude.v12n3.4244

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Cholinergic agonist reverses H1-induced memory deficit in mice

Autor: C.E.M. Fernandes, K.R. Serafim, Rosana Mattioli, A.C.L. Gianlorenço

Publikováno v: Progress in neuro-psychopharmacologybiological psychiatry. 72

This study investigated the effects of bilateral intraamygdalar microinjections of PNU-282987, a nicotinic cholinergic agonist, on anxiety and the reversal of amnesia induced by chlorpheniramine (CPA), an H1 histaminergic antagonist, in mice subjecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a60799bb22037ec56f3c76bf612e36
https://pubmed.ncbi.nlm.nih.gov/27528108

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Emotional memory consolidation impairment induced by histamine is mediated by H1 but not H2 receptors

Autor: Azair Canto-de-Souza, A.C.L. Gianlorenço, Rosana Mattioli, K.R. Serafim

Publikováno v: Brain Research Bulletin. 89(5-6):197-202

Histaminergic fibers are present in the molecular and granular layers of the cerebellum and have high density in the vermis and flocculus. Evidence indicates that the cerebellar vermis is involved in memory consolidation. Recently, we demonstrated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6b32b8b64dffeac463be3126ce937c

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