Zobrazeno 1 - 10
of 36
pro vyhledávání: '"K.P. Steed"'
Publikováno v:
Journal of Allergy and Clinical Immunology. 104:s253-s257
The imaging technique of gamma scintigraphy has been used to quantify the total amount of drug deposited in the lungs and the pattern of regional lung deposition, for formulations of Berodual (Boehringer Ingelheim GmbH) delivered from pressurized met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460ba902b4fab79e407b791854ba6200
https://doi.org/10.1016/s0091-6749(99)70042-4
https://doi.org/10.1016/s0091-6749(99)70042-4
Publikováno v:
Respiratory Medicine. 93:424-431
The Spacehaler (Evans Medical Ltd, Leatherhead, U.K.) is a new, compact, inhaler device containing the same aerosol canister as a conventional metered dose inhaler (MDI). However, the design of the Spacehaler has been shown to reduce the velocity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c3d217b274ef36c183337747d08dd1
https://doi.org/10.1053/rmed.1999.0587
https://doi.org/10.1053/rmed.1999.0587
Publikováno v:
Journal of Controlled Release. 49:115-122
In the early stages of product development for novel colonic delivery systems, considerable time can be lost in establishing the likely potential of any given research strategy because of a lack of suitable in vitro or animal models. We therefore rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da9091ffe46794d6a7480cb4ba8f10fd
https://doi.org/10.1016/s0168-3659(97)00062-x
https://doi.org/10.1016/s0168-3659(97)00062-x
Publikováno v:
European Journal of Pharmaceutical Sciences. 5:55-61
A novel pocket-sized multidose nebuliser device (Respimat, Boehringer Ingelheim) has been developed for the delivery of asthma medications. The lung and oropharyngeal deposition patterns of an aqueous fenoterol formulation delivered from a prototype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a80537357e453be5e6e5ebd1d0d2d8e9
https://doi.org/10.1016/s0928-0987(96)00016-4
https://doi.org/10.1016/s0928-0987(96)00016-4
Publikováno v:
International Journal of Pharmaceutics. 112:199-206
Eight healthy male volunteers were recruited for a study to determine the in vivo behaviour of an enteric coated, modified release beclomethasone dipropionate formulation. The non-invasive technique of gamma scintigraphy was used to relate position a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a23c26ecc40f826907736c57c9427fa
https://doi.org/10.1016/0378-5173(94)90355-7
https://doi.org/10.1016/0378-5173(94)90355-7
Publikováno v:
International Journal of Pharmaceutics. 101:263-268
The distribution in the gastrointestinal tract of a radiolabelled drug-resinate formulation, administered in the form of an oral suspension, and the concomitantly administered water wash, was investigated using the technique of dual-isotope gamma sci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::746f4818fd6ca8d28e8637e584b0c756
https://doi.org/10.1016/0378-5173(94)90222-4
https://doi.org/10.1016/0378-5173(94)90222-4
Autor:
Robin C. Spiller, Colin D. Melia, L. Barrow, Clive G. Wilson, Peter James Watts, M. C. Davies, K.P. Steed
Publikováno v:
International Journal of Pharmaceutics. 87:215-221
Gamma scintigraphy has been used to compare the colonic transit rate of different sizes of radiolabelled model dosage forms in healthy human subjects. Studies simultaneously compared the ascending colon residence time of 111In-labelled 0.2 mm ion-exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::619564983346f5a5016a5dd884e538f3
https://doi.org/10.1016/0378-5173(92)90245-w
https://doi.org/10.1016/0378-5173(92)90245-w
Publikováno v:
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine. 20(1)
Respimat Soft Mist() inhaler (SMI) is a novel multidose propellant-free inhaler device for delivery of inhaled drugs to patients with asthma and chronic obstructive pulmonary disease. In vitro studies have been undertaken to assess facial and ocular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be124b92d00f0a535d7cb4537096f4f8
https://pubmed.ncbi.nlm.nih.gov/17388748
https://pubmed.ncbi.nlm.nih.gov/17388748
Publikováno v:
International Journal of Pharmaceutics. 123:291-293
We report for the first time the deposition pattern in the respiratory tract of a metered dose inhaler formulated with hydrofluoroalkane (HFA) 134a, in comparison with an inhaler containing chlorofluorocarbon (CFC) 12. The inhalers delivered 125 μg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f491fe3faf5e69dc976abf325d807537
https://doi.org/10.1016/0378-5173(95)00150-h
https://doi.org/10.1016/0378-5173(95)00150-h
Publikováno v:
Journal of Aerosol Medicine. 7:177-179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b0aef11625de9abf6036e5111159fa7
https://doi.org/10.1089/jam.1994.7.177
https://doi.org/10.1089/jam.1994.7.177