Zobrazeno 1 - 10
of 19
pro vyhledávání: '"K.P. Goetsch"'
Publikováno v:
BioTechniques. 58:25-32
Skeletal muscle injury elicits the activation of satellite cells and their migration to the wound area for subsequent terminal differentiation and tissue integration. However, interstitial fibroblasts recruited to the site of injury promote depositio
Publikováno v:
Journal of Cellular Biochemistry. 115:1299-1307
Satellite cell migration is critical for skeletal muscle growth and regeneration. Controlled cell migration is dependent on the formation of mature focal adhesions between the cell and the underlying extracellular matrix (ECM). These cell-ECM interac
Autor:
Carola U. Niesler, K.P. Goetsch
Publikováno v:
Biochemical and biophysical research communications. 479(2)
Muscular injuries that destroy the basal lamina result in poor functional recovery of skeletal muscle. This is due, in part, to the deposition of structural fibrotic proteins such as fibronectin and collagen by fibroblasts and other cells. Transformi
Publikováno v:
Matrix Biology. 30:109-117
Extracellular matrix factors, specifically fibronectin and collagen I, are essential for structural support during muscle regeneration. Decorin has been identified as an anti-fibrotic agent with binding sites located on both fibronectin and collagen
Publikováno v:
Growth factors (Chur, Switzerland). 33(3)
Hepatocyte growth factor (HGF) regulates satellite cell activation, proliferation, and differentiation. We analyzed the dose-dependent effects of HGF on myogenesis. Murine C2C12 and human donor-derived skeletal muscle myoblasts were treated with 0, 2
Autor:
K.P. Goetsch, Carola U. Niesler
Publikováno v:
Analytical Biochemistry. 411:158-160
Myoblast migration is essential for muscle development, regeneration, and repair. Various assays are available for the study of migration; however, many are not suitable for the analysis of myoblast migration during skeletal muscle wound repair. Furt
Publikováno v:
Journal of muscle research and cell motility. 34(5-6)
Skeletal muscle repair requires the migration of myoblasts (activated satellite cells) both to the injury site and then within the wound to facilitate cellular alignment in preparation for differentiation, fusion and eventual healing. Along this jour
Publikováno v:
Frontiers in Physiology
Bioengineering skeletal muscle often requires customized equipment and intricate casting techniques. One of the major hurdles when initially trying to establish in vitro tissue engineered muscle constructs is the lack of consistency across published
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Akademický článek
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