Zobrazeno 1 - 10
of 149
pro vyhledávání: '"K.O. Lindros"'
Publikováno v:
Cell Biology and Toxicology. 13:257-262
Within the liver acinus the majority of genes are expressed in an ascending or descending gradient from the portal to the central vein. The regulatory factors involved in this spatial pattern of gene expression are still poorly understood. Many liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2728b9b97f388c1c09212a586690e551
https://doi.org/10.1023/a:1007479223229
https://doi.org/10.1023/a:1007479223229
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 8(4)
The flavonoid silymarin and its main active component silybin have been used in the treatment of toxic liver diseases. In order to evaluate the hepatoprotective potency of both these compounds, their effects on the viability, lipid peroxidation and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95cd0f77c967970c219de066ecadd47
https://pubmed.ncbi.nlm.nih.gov/20692965
https://pubmed.ncbi.nlm.nih.gov/20692965
Publikováno v:
Toxicology in Vitro. 8:577-579
The effects of the hepatoprotective compound silymarin on hepatocytes in primary culture were studied. Exposure of cells in primary culture (both conventional cells and perivenous or periportal cells isolated by the digitonin-collagenase perfusion te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f77580aabcff772b46321b6b91a31d0
https://doi.org/10.1016/0887-2333(94)90020-5
https://doi.org/10.1016/0887-2333(94)90020-5
Publikováno v:
FEBS letters. 327(2)
The CYP2B1/2 gene pair is an example of many liver genes that exhibit a characteristic zonated expression pattern in the liver. The factors governing this zonation are poorly understood. We observed that after hypophysectomy the expression of CYP2B1/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a4da5bafbb29cbf574099b4c8e685f
https://pubmed.ncbi.nlm.nih.gov/8335114
https://pubmed.ncbi.nlm.nih.gov/8335114
Recent studies with liver slices, perfused liver and hepatocytes have shown that the rate of ethanol metabolism is dependent on the concentrations of ethanol. In order to study whether this occurs in vivo, we studied the rate of ethanol elimination i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07dded59e33afed171a6f1698bf57727
https://doi.org/10.1016/b978-0-12-691403-0.50036-7
https://doi.org/10.1016/b978-0-12-691403-0.50036-7
Publikováno v:
Toxicology letters. 9(2)
Penetration of acetaldehyde into cerebrospinal fluid (CSF) was studied in healthy human volunteers during calcium carbimide-ethanol interaction. CSF was sampled via lumbar puncture and blood from a cubital vein. CSF and blood acetaldehyde concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4dade013156c986a243867060ae583
https://pubmed.ncbi.nlm.nih.gov/7302982
https://pubmed.ncbi.nlm.nih.gov/7302982
Autor:
J.D. Sinclair, K.O. Lindros
Publikováno v:
Pharmacology, biochemistry, and behavior. 14(3)
Calcium cyanamide, an aldehyde dehydrogenase (ALDH) inhibitor used in the treatment of alcoholism, strongly suppressed voluntary ethanol drinking by rats. Such inhibitors have generally been believed to act primarily by limiting drinking through acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f3d0a9a9186b23304bfab8843cc075
https://pubmed.ncbi.nlm.nih.gov/7232463
https://pubmed.ncbi.nlm.nih.gov/7232463
Autor:
S. Zimatkin, K.O. Lindros
Publikováno v:
Alcohol (Fayetteville, N.Y.). 6(4)
Brain samples from rats genetically selected for high or low voluntary alcohol intake (AA and ANA strains) or for differences in alcohol-induced motor incoordination (AT and ANT strains) were analyzed by histochemistry for aldehyde dehydrogenase (EC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16c88d57db2d05afd743da76250e378
https://pubmed.ncbi.nlm.nih.gov/2765201
https://pubmed.ncbi.nlm.nih.gov/2765201
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