Transient anti-cytokine autoantibodies superimpose the hyperinflammatory response in Kawasaki disease and multisystem inflammatory syndrome in children: a comparative cohort study on correlates of diseaseResearch in context

Autor: Stejara A. Netea, Giske Biesbroek, Diana van Stijn, Hanna Ijspeert, Caspar I. van der Made, Machiel H. Jansen, Judy Geissler, J.M. (Merlijn) van den Berg, Martijn van der Kuip, Mariken P. Gruppen, Dieneke Schonenberg-Meinema, Berber Kapitein, A.M. (Marceline) Tutu van Furth, Sietse Q. Nagelkerke, Dasja Pajkrt, Frans B. Plötz, M.E.J. (Lisette) den Boer, Gijs W. Landman, Marlies A. van Houten, Ines Goetschalckx, Erik J.M. Toonen, Frank L. van de Veerdonk, Irene M. Kuipers, Willem A. Dik, Taco W. Kuijpers, T. Hendriks, M.K. Felderhof, N.M. Weggelaar, L. Filippini, L. Rozendaal, M. Groeneweg, R. Nuboer, M. Bruijn, K.M. Dolman, J.G. Noordzij, J.P. de Winter, A.M. Vlieger, F.B. Plötz, L.C. Delemarre

Publikováno v: EBioMedicine, Vol 95, Iss , Pp 104736- (2023)

Summary: Background: Children with SARS-CoV-2 related Multisystem Inflammatory Syndrome in Children (MIS-C) often present with clinical features that resemble Kawasaki disease (KD). Disease severity in adult COVID-19 is associated to the presence of

Externí odkaz: https://doaj.org/article/93828e5e066e4179b2b6ff7905fc558a

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Elastase, but not proteinase 3 (PR3), induces proteinuria associated with loss of glomerular basement membrane heparan sulfate after in vivo renal perfusion in rats

Autor: Elisabeth Brouwer, M. G. Huitema, M. R. Daha, Peter Heeringa, Pieter Klok, C. G. M. Kallenberg, J. van den Born, Marinka A.H. Bakker, Jhm Berden, K.M. Dolman, Pieter Limburg

Publikováno v: Scopus-Elsevier
Clinical and Experimental Immunology, 105, 321-329
Clinical and Experimental Immunology, 105, 2, pp. 321-329
Clinical and Experimental Immunology, 105, pp. 321-329

Elastase, but not PR3, induces proteinuria associated with loss of glomerular basement membrane (GBM) heparan sulphate after in vivo renal perfusion in rats. PR3 and elastase are cationic neutral serine proteinases present in the azurophilic granules

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb40607f0b52387e02f8405d1a1c373
https://doi.org/10.1046/j.1365-2249.1996.d01-754.x

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