Zobrazeno 1 - 10 of 138 pro vyhledávání: '"K.H. Chadwick"'
1
Dose–effect relationships, epidemiological analysis and the derivation of low dose risk
Autor: K.H. Chadwick, H P Leenhouts
Publikováno v: Journal of Radiological Protection. 31:95-105
This paper expands on our recent comments in a letter to this journal about the analysis of epidemiological studies and the determination of low dose RBE of low LET radiation (Chadwick and Leenhouts 2009 J. Radiol. Prot. 29 445-7). Using the assumpti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97cc18cf1cc449093be946db571c6d3
https://doi.org/10.1088/0952-4746/31/1/006
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3
What can we say about the dose-effect relationship at very low doses?
Autor: H P Leenhouts, K.H. Chadwick
Publikováno v: Journal of Radiological Protection. 22:A155-A158
This paper uses a few sets of low-dose experimental radiobiological data to examine just what these data sets say with respect to the shape of the dose-effect relationship at very low doses. The examination of the data leads to the conclusion that ne
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f76624ae18fb958e0a2181dc8e7f7e
https://doi.org/10.1088/0952-4746/22/3a/327
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5
Multistage carcinogenesis modeling and the initiation event
Autor: H.P. Leenhouts, K.H. Chadwick
Publikováno v: Radiation Oncology Investigations. 5:129-133
Carcinogenesis is generally considered to be a multistage process classified under "initiation," "promotion," and "progression," and it is therefore of interest to know how radiation might affect them. Models which are currently being used with some
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9181873b0a9c7760ba04bfaecabf13e
https://doi.org/10.1002/(sici)1520-6823(1997)5:3<129::aid-roi9>3.0.co
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6
Radiation risk is linear with dose at low doses
Autor: H P Leenhouts, K.H. Chadwick
Publikováno v: The British Journal of Radiology. 78:8-10
This paper presents a brief argument, based on a mechanistic approach, to show that radiation risk is linear with radiation dose from zero dose up. Similarities in cellular effects lead to the assumption of a common mechanism and the DNA double stran
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ed87efbed10689b9e38cbca68b8168
https://doi.org/10.1259/bjr/51173413
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7
Radiation Protection Research in the European Union
Autor: G. Desmet, J. Sinnaeve, M. Olast, A. Karaoglou, G.N. Kelly, H.G. Menzel, K.H. Chadwick, H. Schibilla
Publikováno v: Radiation Protection Dosimetry. 68:127-136
A brief review is presented of both the formal and scientific development of the European Commission's Radiation Protection Research programme from its inception in 1958 through to the present day. The recent additional research programme on the Radi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85c7f89da7f1e023b184e275619c6fa8
https://doi.org/10.1093/oxfordjournals.rpd.a031843
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10
A two-mutation model of radiation carcinogenesis: application to lung tumours in rodents and implications for risk evaluation
Autor: H P Leenhouts, K.H. Chadwick
Publikováno v: Journal of Radiological Protection. 14:115-130
An attempt is made to develop a model for radiation carcinogenesis linking DNA damage to malignancy. A modification of the two-stage model for carcinogenesis developed by Knudson and Moolgavkar (see J. Natl. Acad. Sci. (USA), vol. 68, p. 1037-52, 198
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fd0fe6c55c26fcb2d333b453ec59854
https://doi.org/10.1088/0952-4746/14/2/002
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