Výsledky vyhledávání

Influence of alpha-1 antitrypsin heterozygosity on treatment efficacy of HCV combination therapy

Autor: Hanneke van Soest, K.F. Kok, Martijn G.H. van Oijen, Antonius E. van Herwaarden, Greet J. Boland, Richard A. de Vries, Thomas Berg, Joost P.H. Drenth, Juliane Halangk

Publikováno v: European Journal of Gastroenterology & Hepatology, 22, 808-12
European journal of gastroenterology & hepatology, 22(7), 808-812. Lippincott Williams and Wilkins
European Journal of Gastroenterology & Hepatology, 22, 7, pp. 808-12

Background The role of heterozygosity for alpha-1 antitrypsin (A1AT) alleles in patients with chronic hepatitis C virus (HCV) is unclear. There is limited evidence to suggest that there is an increased prevalence of heterozygous A1AT carriers in HCV,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f498716385c845e09bb1618a15e84f9
http://hdl.handle.net/2066/88034

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Vitamin K deficiency bleeding in cholestatic infants with alpha-1-antitrypsin deficiency

Autor: L van Vlerken, P. M. van Hasselt, T. J. de Koning, R. de Vries, K.F. Kok, E Nieuwenhuys, Roderick H. J. Houwen, A D M Vorselaars

Publikováno v: ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 94(6), F456-F460. BMJ PUBLISHING GROUP
Archives of Disease in Childhood : Fetal and Neonatal Edition, 94, 6, pp. F456-60
Archives of Disease in Childhood : Fetal and Neonatal Edition, 94, F456-60

Item does not contain fulltext OBJECTIVE: Exclusively breastfed infants with unrecognised cholestatic jaundice are at high risk of a vitamin K deficiency (VKD) bleeding. It is presently unknown whether (the size of) this risk depends on the degree of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ea00741886521e5a9e5700000edad1
https://doi.org/10.1136/adc.2008.148239

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479 LIVER TRANSPLANTATION FOR ALPHA-1 ANTITRYPSIN DEFICIENCY: HEPATOCELLULAR CARCINOMA IS COMMON AND DETERIORATES SURVIVAL

Autor: K.F. Kok, Robert J. Porte, Rene Scheenstra, A. van den Berg, B. van Hoek, J.P.H. Drenth, René Adam, Herold J. Metselaar, M. G. H. van Oijen

Publikováno v: Journal of Hepatology. 52:S193-S194

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93ab3a904113dca7921fd28a54668a1d
https://doi.org/10.1016/s0168-8278(10)60481-3

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Prevalence of genetic polymorphisms in the promoter region of the alpha-1 antitrypsin (SERPINA1) gene in chronic liver disease: a case control study

Autor: Joost P.H. Drenth, K.F. Kok, Martijn G.H. van Oijen, Rene H. M. te Morsche

Publikováno v: BMC Gastroenterology
BMC Gastroenterology, 10, pp. 22-22
BMC Gastroenterology, 10, 22-22
BMC Gastroenterology, Vol 10, Iss 1, p 22 (2010)

Background Alpha-1 antitrypsin (A1AT) deficiency, caused by the Z allele (p.E342K) and S allele (p.E264V) in the SERPINA1 gene, can induce liver and pulmonary disease. Different mechanisms appear to be responsible for the pathogenesis of these diverg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3297b8cd9dc54ba7cf7ca244c8c103
https://hdl.handle.net/2066/89639

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