PT07.3: A Critical Assessment of CT as a Valid Means of Skeletal Muscle Analysis and Muscular Body Composition Analysis in Cancer Cachexia

Autor: Stephen J. Wigmore, Carsten Jacobi, Chris Deans, K.C.H. Fearon, Janice Miller, Michael I Ramage, Richard J E Skipworth

Publikováno v: Clinical Nutrition. 38:S47-S48

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7fe61024fca25cb26f586adbfcffc321
https://doi.org/10.1016/s0261-5614(19)32578-6

Guidelines for Perioperative Care in Elective Rectal/Pelvic Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations

Autor: J. Nygren, J. Thacker, F. Carli, K.C.H. Fearon, S. Norderval, D.N. Lobo, O. Ljungqvist, M. Soop, J. Ramirez

Publikováno v: World Journal of Surgery. 37:285-305

This review aims to present a consensus for optimal perioperative care in rectal/pelvic surgery, and to provide graded recommendations for items for an evidenced-based enhanced recovery protocol.Studies were selected with particular attention paid to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d4379fc9fa27c8eb4e179d2c0acf31
https://doi.org/10.1007/s00268-012-1787-6

Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2α may signal skeletal muscle atrophy in weight-losing cancer patients

Autor: Michael J. Tisdale, Helen L. Eley, Richard J E Skipworth, K.C.H. Fearon, D A C Deans

Publikováno v: Eley, H L, Skipworth, R J E, Deans, D A C, Fearon, K C H & Tisdale, M J 2008, ' Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2alpha may signal skeletal muscle atrophy in weight-losing cancer patients ', British Journal of Cancer, vol. 98, no. 2, pp. 443-449 . https://doi.org/10.1038/sj.bjc.6604150
British Journal of Cancer

Previous studies suggest that the activation (autophosphorylation) of dsRNA-dependent protein kinase (PKR) can stimulate protein degradation, and depress protein synthesis in skeletal muscle through phosphorylation of the translation initiation facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1c5d40c18a8a93c13af230274a1be6
https://doi.org/10.1038/sj.bjc.6604150

The response of leptin, interleukin-6 and fat oxidation to feeding in weight-losing patients with pancreatic cancer

Autor: Tom Preston, Donald C. McMillan, A M Wallace, K.C.H. Fearon, James A. Ross, Matthew D. Barber

Publikováno v: Barber, M D, McMillan, D C, Wallace, A M, Ross, J A, Preston, T & Fearon, K C H 2004, ' The response of leptin, interleukin-6 and fat oxidation to feeding in weight-losing patients with pancreatic cancer ', British Journal of Cancer, vol. 90, no. 6, pp. 1129-32 . https://doi.org/10.1038/sj.bjc.6601712
British Journal of Cancer

At baseline, weight-losing pancreatic cancer patients (n=7) had lower leptin (P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d43cafe48e40f58c683243e3edb272b
https://doi.org/10.1038/sj.bjc.6601712

Nutritional support in cancer

Autor: K.C.H. Fearon

Publikováno v: Clinical Nutrition. 20:187-190

The mechanisms and mediators behind the complex syndrome of cancer cachexia are being elucidatedslowly. Recent evidence suggests that pro-inflammatory cytokines and tumour-specific cachectic factors may be important. The failure of conventional nutri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c26104183268dd5e85783fc7eca9b65
https://doi.org/10.1054/clnu.2001.0414