Zobrazeno 1 - 10
of 107
pro vyhledávání: '"K.A. Eidne"'
Autor:
Song Zhang, P.A. Findlay, Dominique Blache, Graeme Martin, K.A. Eidne, Margaret Blackberry, Clare Lesley Adam, Philip E. Vercoe
Publikováno v:
Regulatory Peptides. 124:81-87
Orexins exert their effects through two specific receptors (OX1R and OX2R) that have been found mainly in the brain and also in peripheral tissues of rats and humans. Here, we demonstrate expression of mRNA encoding for ovine OX1R and OX2R in central
Publikováno v:
Endocrinology. 141:299-306
This study examined the mechanism underlying the rat GnRH receptor (GnRH-R) internalization pathway by investigating the role of added/extended C-terminal tails and the effect of beta-arrestins and dynamin. The internalization of the wild-type (WT) r
Publikováno v:
Molecular and Cellular Endocrinology. 144:11-19
The objective of this study was to determine whether the gonadotrophin-releasing hormone (GnRH) ligand binds to the GnRH receptor (GnRH-R) with either the N- and C-termini or the beta-II turn pointing towards the cell. The functionality of GnRH and t
Publikováno v:
Molecular and Cellular Endocrinology. 95:R11-R15
Thyrotrophin-releasing hormone (TRH) is a hypothalamic tripeptide known to act via its receptor in the anterior pituitary gland to stimulate the release of thyrotrophin (TSH) from thyrotrophs and prolactin (PRL) from lactotrophs. It is also thought t
Publikováno v:
Neuroscience. 53:877-887
The distribution sites of messenger RNA encoding for the thyrotrophin-releasing hormone receptor have been studied in rat pituitary and brain. A specific 35 S-labelled riboprobe generated from a rat thyrotrophin-releasing hormone receptor complementa
Publikováno v:
Biology of Reproduction. 43:305-311
Gonadotropin-releasing hormone (GnRH) and related peptides are implicated in the local control of rat ovarian function, but evidence to date for direct effects of such peptides on primate ovarian cells is equivocal. In contrast to rat ovaries, where
Publikováno v:
Molecular human reproduction. 2(2)
Gonadotrophin-releasing hormone (GnRH) receptors are present on the ovary as well as in the anterior pituitary gland. GnRH analogues may exert their actions in part via these ovarian receptors. However, in the primate ovary, GnRH receptors are of low
Publikováno v:
Journal of molecular endocrinology. 11(2)
The cloning and characterization of the mouse TRH receptor (TRH-R) gene revealed an untranslated exon (exon 1), a single intron and an upstream dinucleotide repeat sequence (d(TG)16.d(AG)21) in the 5′ untranslated region (UTR). The coding region wa
Publikováno v:
Molecular and cellular endocrinology. 95(1-2)
We have used the technique of quantitative in situ hybridization in order to study the changes in the levels of expression of D2 receptor mRNA in the anterior pituitary gland of female rats at different stages of the reproductive cycle. Plasma prolac
Autor:
K.A. Eidne, Philippa T. K. Saunders, J. Brooks, Alan S. McNeilly, W. J. Struthers, Philip L. Taylor
Publikováno v:
Molecular and cellular endocrinology. 94(2)
We have isolated a full length cDNA clone coding for the sheep GnRH receptor (GnRH-R). The amino acid sequence shows greater homology to the human GnRH-R sequence than the two rodent receptors published so far. We have also carried out physiological