Zobrazeno 1 - 10
of 59
pro vyhledávání: '"K.A. DeSante"'
Publikováno v:
Journal of Pharmaceutical Sciences. 77:153-156
Pinacidil [(+/-)-2-cyano-1-(4-pyridyl)-3-(1,2,2-trimethylpropyl)guanidine monohydrate] is a novel, direct-acting vasodilator antihypertensive agent. The cyano 14C-labeled drug is rapidly and completely absorbed after an oral 12.5-mg dose in solution.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11056bb275a8595abeb77224a543185a
https://doi.org/10.1002/jps.2600770212
https://doi.org/10.1002/jps.2600770212
Publikováno v:
Journal of Pharmaceutical Sciences. 66:1713-1716
Plasma level data on two investigational capsule formulations of propoxyphene with similar physicochemical parameters demonstrate that the formulations have different in vivo bioavailabilities. The potential for bioavailability problems with water-so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51468a23d13dbd703b4b8bbc48d6bd9c
https://doi.org/10.1002/jps.2600661214
https://doi.org/10.1002/jps.2600661214
Publikováno v:
The Journal of Clinical Pharmacology. 20:428-436
The pharmacokinetic and biopharmaceutic profiles of a single dose of oral cortisone acetate were developed for 23 healthy normal adult volunteers using cortisone and cortisol plasma concentration data. Cortisone acetate was rapidly absorbed and conve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7f7460b60901d05ac774ce5a38b2eb
https://doi.org/10.1002/j.1552-4604.1980.tb01715.x
https://doi.org/10.1002/j.1552-4604.1980.tb01715.x
Publikováno v:
Journal of Pharmaceutical Sciences. 68:586-588
Oral coadministration of a single 250-mg tetracycline capsule and 60 ml of a bismuth subsalicylate antidiarrheal mixture reduced tetracycline absorption by 34% without appearing to perturb its absorption or disposition rate. A pronounced increase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2973ed6386da71407f9206a4932cc45
https://doi.org/10.1002/jps.2600680518
https://doi.org/10.1002/jps.2600680518
Publikováno v:
Journal of clinical pharmacology. 19(11-12)
Since it has been reported by several authors that colestipol HCl and clofibrate have an additive effect in lowering serum cholesterol levels, it was felt advisable to evaluate the blood levels of clofibrate when given simultaneously with colestipol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db474fa08ec845094afd451f939191ab
https://pubmed.ncbi.nlm.nih.gov/536468
https://pubmed.ncbi.nlm.nih.gov/536468
Publikováno v:
Journal of pharmaceutical sciences. 67(11)
The effect of a kaolin--pectin antidiarrheal suspension on the bioavailability of orally administered clindamycin was evaluated by model-dependent pharmacokinetic techniques. Each subject's serum clindamycin concentration--time data in the absence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f07d0d07aad6a97d6d0792ebc929e1c
https://pubmed.ncbi.nlm.nih.gov/712595
https://pubmed.ncbi.nlm.nih.gov/712595
Autor:
K.A. Desante, A.R. Disanto
Publikováno v:
Journal of pharmaceutical sciences. 64(1)
In a clinical study involving 22 normal adult volunteers, the bioavailability and pharmacokinetics of prednisone tablets with varying dissolution rates were evaluated. Serum levels were measured by a radioimmunoassay for prednisolone. Absorption rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cce0d4713e4ed67d99ae25538910bae
https://pubmed.ncbi.nlm.nih.gov/1133681
https://pubmed.ncbi.nlm.nih.gov/1133681
Publikováno v:
Journal of pharmaceutical sciences. 68(10)
The variability and relative bioavailability of methylprednisolone tablets were evaluated utilizing a double Latin square crossover design in which each of 20 subjects was given four of five treatments. Three different lots of methylprednisolone tabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5580bdea860f0f4ce570a7824107f7
https://pubmed.ncbi.nlm.nih.gov/512868
https://pubmed.ncbi.nlm.nih.gov/512868
Publikováno v:
Journal of clinical pharmacology. 14(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dade7451ae837c12ad72f8bef331eee
https://pubmed.ncbi.nlm.nih.gov/4610015
https://pubmed.ncbi.nlm.nih.gov/4610015
Publikováno v:
Journal of clinical pharmacology. 21(10)
Serum and saliva levels of lincomycin were determined in 15 normal adult male volunteers after a single intramuscular injection of 600, 1000, or 1500 mg lincomycin in a three-way crossover study. The area under the serum concentration—time curve di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02daeadee411617b1be577ee766515d
https://pubmed.ncbi.nlm.nih.gov/7309904
https://pubmed.ncbi.nlm.nih.gov/7309904