Ferroelectricity of HfZrO2 in Energy Landscape With Surface Potential Gain for Low-Power Steep-Slope Transistors

Autor: Min Hung Lee, Y.-T. Wei, C. Liu, J.-J. Huang, Ming Tang, Yu-Lun Chueh, K.-Y. Chu, Miin-Jang Chen, Heng-Yuan Lee, Yu-Sheng Chen, Li-Heng Lee, Ming-Jinn Tsai

Publikováno v: IEEE Journal of the Electron Devices Society, Vol 3, Iss 4, Pp 377-381 (2015)

The corresponding energy landscape and surface potential are deduced from the experimental ferroelectricity of HfZrO2 (HZO) for low-power steep-slope transistor applications. The anti-ferroelectric (AFE) in annealed 600°C HZO extracted electrostatic

Externí odkaz: https://doaj.org/article/cd46b1748eca4e00a2406d9c1b19c7f8

Self-Replication of Prion Protein Fragment 89-230 Amyloid Fibrils Accelerated by Prion Protein Fragment 107-143 Aggregates

Autor: Tomas Sneideris, Mantas Ziaunys, Brett K.-Y. Chu, Rita P.-Y. Chen, Vytautas Smirnovas

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 19, p 7410 (2020)

Prion protein amyloid aggregates are associated with infectious neurodegenerative diseases, known as transmissible spongiform encephalopathies. Self-replication of amyloid structures by refolding of native protein molecules is the probable mechanism

Externí odkaz: https://doaj.org/article/f9968bff96fd4106b07e0a94f4004c47

Cross-Seeding Assay in the Investigation of the Amyloid Core of Prion Fibrils

Autor: Brett K-Y, Chu, Yu-Sheng, Lin, Howard C-H, Shen, Rita P-Y, Chen

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2551

Amyloidogenesis, self-propagation of protein or peptide monomers to amyloid fibrils, has been linked to incurable pathogenesis of neurodegenerative diseases such as Alzheimer's disease and prion diseases. Investigations of amyloid structures and how

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::01f33995f77267675eca81cec1ebef7e
https://pubmed.ncbi.nlm.nih.gov/36310229

Impact of HLA polymorphism on the immune response to bacillus anthracis Protective Antigen in vaccination versus natural infection

Autor: Stephanie Ascough, Rebecca J. Ingram, Karen K. Y. Chu, Stephen J. Moore, Theresa Gallagher, Hugh Dyson, Mehmet Doganay, Gökhan Metan, Yusuf Ozkul, Les Baillie, E. Diane Williamson, John H. Robinson, Bernard Maillere, Rosemary J. Boyton, Daniel M. Altmann

Publikováno v: Ascough, S, Ingram, R J, Chu, K K Y, Moore, S J, Gallagher, T, Dyson, H, Doganay, M, Metan, G, Ozkul, Y, Baillie, L, Williamson, E D, Robinson, J H, Maillere, B, Boyton, R J, Altmann, D M & Dory, D (ed.) 2022, ' Impact of HLA polymorphism on the immune response to bacillus anthracis Protective Antigen in vaccination versus natural infection ', Vaccines, vol. 10, no. 10, 1571 . https://doi.org/10.3390/vaccines10101571
Vaccines; Volume 10; Issue 10; Pages: 1571

© 2022 by the authors.The causative agent of anthrax, Bacillus anthracis, evades the host immune response and establishes infection through the production of binary exotoxins composed of Protective Antigen (PA) and one of two subunits, lethal factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f083cd57dd616f27422a23507de6cb7
https://pure.qub.ac.uk/en/publications/2b9305f4-82c8-486b-a36c-0a5f58e8ebcd

Location of the cross‐β structure in prion fibrils: A search by seeding and electron spin resonance spectroscopy

Autor: Brett K.‐Y. Chu, Ruei‐Fong Tsai, Chien‐Lun Hung, Yun‐Hsuan Kuo, Eric H.‐L. Chen, Yun‐Wei Chiang, Sunney I. Chan, Rita P.‐Y. Chen

Publikováno v: Protein Sci

Prion diseases are transmissible fatal neurodegenerative disorders spreading between humans and other mammals. The pathogenic agent, prion, is a protease‐resistant, β‐sheet‐rich protein aggregate, converted from a membrane protein called PrP(C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d40b2ca4f70cbaefdebc55f919edc4
https://europepmc.org/articles/PMC9112485/