Zobrazeno 1 - 10
of 74
pro vyhledávání: '"K.-L. Paul Sung"'
Autor:
K. L. Paul Sung, Wei Huang, Peter C. Chen, Chunli Wang, Chunming Xu, Qingjia Chi, Cheng Chen, Peixing Chen, Yongqiang Sha, Kang Xu, Li Yang
Publikováno v:
Biotechnology Letters. 42:1567-1579
Interleukin (IL)-1β in the joint cavity increases to promote healing after anterior cruciate ligament (ACL) injury. Synovial tissue is a major joint microenvironmental regulator after ACL injury. The purpose of this study was to investigate the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2fa76ddb546465c74e278f0b4b5f7ab
https://doi.org/10.1007/s10529-020-02870-9
https://doi.org/10.1007/s10529-020-02870-9
Autor:
Liwei Zheng, Cheng Chen, Wenbin Yang, K. L. Paul Sung, Jing Xie, Xuedong Zhou, Chunli Wang, Jue Wang
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 12:e550-e565
The healing mechanism of cruciate ligaments is not well elucidated. Crosstalk between adjacent tissues in the knee joint plays an important role in wound healing and tissue regeneration, but the gelatinase modulation in posterior cruciate ligament fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e239818610bfbd5484a6edff43e0f2
https://doi.org/10.1002/term.2325
https://doi.org/10.1002/term.2325
Publikováno v:
Journal of tissue engineering and regenerative medicineREFERENCES. 14(8)
Anterior cruciate ligament (ACL) regeneration is severely affected by the injury-induced overexpression of matrix metalloproteinases (MMPs) and downregulation of lysyl oxidase (LOX). Previous studies have focused on how the expression of MMPs and dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0ea355d2d16ab8725b2ff8d49f7ced
https://pubmed.ncbi.nlm.nih.gov/32483895
https://pubmed.ncbi.nlm.nih.gov/32483895
Publikováno v:
Gene. 766:145149
Background Crosstalk between posterior cruciate ligament fibroblasts (PCLfs) and synoviocytes (SCs) significantly modifies the homeostatic balance of the extracellular matrix (ECM) and appears to post a prominent affection for wound healing of PCL. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ef74112e8d9bc1aa75e8164c9590e7
https://doi.org/10.1016/j.gene.2020.145149
https://doi.org/10.1016/j.gene.2020.145149
Mechano growth factor-C24E, a potential promoting biochemical factor for ligament tissue engineering
Autor:
Yang Song, Chunli Wang, Yonggang Lv, Kang Xu, Xingshuang Ma, K. L. Paul Sung, Can Yu, Li Yang, Juila Li Zhong
Publikováno v:
Biochemical Engineering Journal. 105:249-263
Ligaments play an important role in stabilizing and balancing knee joint movement. Anterior cruciate ligament (ACL) injuries remain a challenge in clinical and experimental settings due to the poor healing potential of ACL injuries. This study invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c03bced100e9fa592487597086011187
https://doi.org/10.1016/j.bej.2015.09.023
https://doi.org/10.1016/j.bej.2015.09.023
Publikováno v:
Connective tissue research. 60(4)
Purposes: To investigate the ability of synoviocytes (SCs) in regulating MMPs expression in the posterior cruciate ligament fibroblasts (PCLfs) after TNF-α treatment, to test whether a specific inflammation inhibitor Bay11-7082 can antagonize the ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e07690ddc57a41f5f7d4459ba9455b
https://pubmed.ncbi.nlm.nih.gov/30372627
https://pubmed.ncbi.nlm.nih.gov/30372627
Publikováno v:
Connective tissue research. 59(4)
Purposes The anterior cruciate ligament (ACL) has poor functional healing response. The synovial tissue surrounding ACL ligament might be a major regulator of the microenvironment in the joint cavity after ACL injury, thus affecting the repair proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878a99df809f3dd09c01621b8af03158
https://pubmed.ncbi.nlm.nih.gov/29431515
https://pubmed.ncbi.nlm.nih.gov/29431515
Autor:
Kang Xu, Nianguo Dong, Li Yang, Yongqiang Sha, Mohanad Kh Al-ani, K. L. Paul Sung, Chunli Wang, Xuefeng Qiu, Yanjun Sun
Publikováno v:
Journal of biomechanics. 66
Current study investigated bone morphogenetic protein 12 (BMP12) and connective tissue growth factor (CTGF) activate tendon derived stem cells (TDSCs) tenogenic differentiation, and promotion of injured tendon regeneration. TDSCs were transfected wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27d31d53aa35c8a7852a833ed1953b8
https://pubmed.ncbi.nlm.nih.gov/29174694
https://pubmed.ncbi.nlm.nih.gov/29174694
Autor:
Li Yang, Peter C. Chen, Chunming Xu, Wei Huang, Jing Xie, Jiahuan Jiang, Yanjun Zhang, K. L. Paul Sung, Yan Xu
Publikováno v:
Injury. 44:893-900
Lysyl oxidase (LOX) family has the capacity to catalyse the cross-linking of collagen and elastin, implicating its important fundamental roles in tissue development and injury healing. However, the variations in expression of the LOX family in the no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcb118531ed13445c30e68eb4178d6a
https://doi.org/10.1016/j.injury.2012.08.046
https://doi.org/10.1016/j.injury.2012.08.046
Autor:
Peter C. Chen, Kevin Zhou, Jing Xie, Chunli Wang, Wei Huang, Lin Yin, Yanjun Zhang, Li Yang, K. L. Paul Sung, Chunmin Xu, Jiahuang Jiang
Publikováno v:
Knee Surgery, Sports Traumatology, Arthroscopy. 22:1997-2006
It was reported that not only ACL but also the synovium may be the major regulator of matrix metalloproteinases (MMPs) in synovial fluids after ACL injury. In order to further confirm whether synovium is capable of regulating the microenvironment in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b245d6fbd27f4b9e74005d77473631c
https://doi.org/10.1007/s00167-013-2425-z
https://doi.org/10.1007/s00167-013-2425-z