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Conjugates of cis-4-Hydroxy-L-proline and Poly(PEG-Lys), a Water Soluble Poly(ether urethane): Synthesis and Evaluation of Antifibrotic Effects in vitro and in vivo

Autor: G J Poiani, J D Fox, David J. Riley, K F Gean, Joachim Kohn, John E. Kemnitzer

Publikováno v: Bioconjugate Chemistry. 5:621-630

Synthetic approaches for the preparation of macromolecular conjugates of the antifibrotic agent cis-4-hydroxy-L-proline (cHyp) were explored, and the efficacy of the conjugates in inhibiting collagen accumulation was investigated in vitro and in vivo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce2b266f8877b7e3f0179416a8c04a1
https://doi.org/10.1021/bc00030a018

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ChemInform Abstract: Preparation, Characterization, and Anticancer Activity of a Series of cis-PtCl2 Complexes Linked to Anthraquinone Intercalators

Autor: R. Ben-Shoshan, Jehoshua Katzhendler, Dan Gibson, Avner Ramu, K.-F. Gean, Israel Ringel

Publikováno v: ChemInform. 22

A new series of complexes of the type cis-PtL2X2 [where L is a monodentate AQ-Y(CH2)nNH2 and L2 is a bidentate AQ-Y(CH2)nNH(CH2)2NH2; AQ = anthraquinone, X = Cl, I, Y = NH, O] in which anthraquinone intercalators are tethered to the cis-PtCl2 unit vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e5934bba491925449a97f3844bec1e9
https://doi.org/10.1002/chin.199124195

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Preparation, characterization and the anticancer activity of a novel series of triaminemonochloroplatinum(II) cations linked to anthraquinone intercalators

Autor: R. Ben-Shoshan, Dan Gibson, Israel Ringel, J. Katzhendler, K.-F. Gean, Avner Ramu

Publikováno v: European Journal of Medicinal Chemistry. 26:593-598

A new series of complexes of the type [PtAm2LCl]+ (where Am = NH3 or Am2 = ethylenediamine and L is a monodentate AQ-Y-(CH2)n-NH2, AQ = anthraquinone, Y = NH, O) was prepared and screened in vitro against P388 leukemia. These complexes displayed high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e3483be39628a94e864f9f7d93126764
https://doi.org/10.1016/0223-5234(91)90193-q

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Preparation, characterization, and anticancer activity of a series of cis-PtCl2 complexes linked to anthraquinone intercalators

Autor: K.-F. Gean, Dan Gibson, Jehoshua Katzhendler, Avner Ramu, Israel Ringel, R. Ben-Shoshan

Publikováno v: Journal of medicinal chemistry. 34(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bcfb76336b9f5ea4e2660631bd7f59
https://pubmed.ncbi.nlm.nih.gov/1992142

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ChemInform Abstract: Synthesis of Aminoanthraquinone Derivatives and Their in vitro Evaluation as Potential Anticancer Drugs

Autor: R. Ben-Shoshan, K.-F. Gean, Zeev Tashma, J. Katzhendler, G. Bar-Ad, Avner Ramu, U. Bachrach, Israel Ringel

Publikováno v: ChemInform. 20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ae1c90880ac18f7f4d21e9ee5ff9de6
https://doi.org/10.1002/chin.198925133

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Preparation,characterization and anticancer activity of novel platinum linked interactions

Autor: Avner Ramu, Dan Gibson, R. Ben-Shoshan, M. Roll, K.-F. Gean, Jehoshua Katzhendler

Publikováno v: Journal of Inorganic Biochemistry. 36:158

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33c45218106f6f4894122bb9bd30ff48
https://doi.org/10.1016/0162-0134(89)84041-3

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