Zobrazeno 1 - 10
of 59
pro vyhledávání: '"K. Zeh"'
Autor:
F Zimmermann, J. Wilbertz, B. Djavidani, K. Zeh, Yi Zhao, Manfred Böhm, Maike Sander, J Wagner, Michael Bader, Detlev Ganten, J. Peters, J. Bachmann, Min Ae Lee, Sebastian Bachmann
Publikováno v:
Cellular and Molecular Biology of the Renin-Angiotensin System ISBN: 9781351070492
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f22cb4a4776eb5487cb9dd69e67c43b1
https://doi.org/10.1201/9781351070492-3
https://doi.org/10.1201/9781351070492-3
Autor:
Eva van der Veer, Amy K. Patick, Leen-Jan van Doorn, Søren Ottosen, Michael R. Hodges, Lu Yang, Anneke K. Raney, K. Zeh, Todd B. Parsley
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:599-608
Miravirsen is a β- d -oxy-locked nucleic acid-modified phosphorothioate antisense oligonucleotide targeting the liver-specific microRNA-122 (miR-122). Miravirsen demonstrated antiviral activity against hepatitis C virus (HCV) genotype 1b replicons w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4635e0c7f702800a1a57fc9f18a5378f
https://doi.org/10.1128/aac.04220-14
https://doi.org/10.1128/aac.04220-14
Autor:
Howard A. Burris, Ramesh K. Ramanathan, Michael Gordon, Lee S. Rosen, Isabelle Rooney, K. Zeh, Raymond W. Liu, Terence Rugg, Jeffrey R. Infante
Publikováno v:
Investigational New Drugs. 31:363-369
Purpose SGX523 is an orally bio-available, ATP competitive, small molecule inhibitor of MET, binding the kinase domain active site in a novel mode. Two phase 1, open-label, dose-escalation studies of SGX523 were conducted to evaluate both interrupted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15dfd062c8687451696ddd037990fd0
https://doi.org/10.1007/s10637-012-9823-9
https://doi.org/10.1007/s10637-012-9823-9
Autor:
Detlev Ganten, Maike Sander, Reinhold Kreutz, K. Zeh, Michael Bader, P. Vecsei, Synthia H. Mellon, J. Peters, Djavidani B
Publikováno v:
Europe PubMed Central
INTRODUCTION The transgenic rat TGR(mREN2)27 is a monogenetic rat model in hypertension research. Integration of mouse Ren-2 gene into the rat genome led to fulminant hypertension despite suppressed plasma and kidney renin concentrations. Renin is hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf5477debb438f529d7eec044209a46
https://doi.org/10.1097/00004872-199506000-00010
https://doi.org/10.1097/00004872-199506000-00010
Autor:
Charles Julian Lindsey, João Bosco Pesquero, Antonio C.M. Paiva, Detlev Ganten, Michael Bader, K Zeh
Publikováno v:
Journal of Biological Chemistry. 269:26920-26925
Bradykinin is a potent vasodilatory peptide hormone involved in a broad range of physiological actions. While it acts through at least two types of receptors which are named B1 and B2, most of its effects are mediated via activation of the B2 recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eb4ac26ec1ba1caa1fb0179dba10063
https://doi.org/10.1016/s0021-9258(18)47107-4
https://doi.org/10.1016/s0021-9258(18)47107-4
Publikováno v:
Journal of Viral Hepatitis. 20:21-22
cialist tests, requested following referral to secondary care services for investigation and management. METHODS: All HCV testing undertaken between 2002 and 2011 were extracted from laboratory information systems of 23 participating centres in Engla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::133bd0ecb1f5c26ae1ef5bd2ed0935fc
https://doi.org/10.1111/jvh.12166_10
https://doi.org/10.1111/jvh.12166_10
Autor:
Arthur A. Levin, Robert Persson, J Rodriguez-Orengo, Michael R. Hodges, A Karim, A Chen, K. Zeh, B King
Publikováno v:
Journal of Viral Hepatitis. 20:22-22
BACKGROUND: Miravirsen sodium is a b-D-oxy-Locked Nucleic Acid (LNA)-modified phosphorothioate anti-sense oligonucleotide inhibitor of the liver-expressed microRNA122 (miR-122). Miravirsen reduces HCV RNA levels indirectly, by targeting the critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b54cdcd31b8e4c5949981b0179f6bac5
https://doi.org/10.1111/jvh.12166_11
https://doi.org/10.1111/jvh.12166_11
Publikováno v:
Molecular Reviews in Cardiovascular Medicine ISBN: 9789401065252
The genetic basis of numerous diseases has been studied by taking advantage of the new techniques offered by molecular biology and medicine. The contributions of classical genetic studies with analyses of linkage between phenotypic changes and genoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5e7b58ee8677041b6c7f89705b294d3
https://doi.org/10.1007/978-94-009-0083-7_7
https://doi.org/10.1007/978-94-009-0083-7_7
Publikováno v:
Journal of Hepatology. 56:S336
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d64a5a78b248dd7563b0c416148149
https://doi.org/10.1016/s0168-8278(12)60875-7
https://doi.org/10.1016/s0168-8278(12)60875-7
Autor:
L.J. van Doorn, E. van der Veer, Amy K. Patick, A. Chen, K. Zeh, Michael R. Hodges, Anneke K. Raney
Publikováno v:
Journal of Hepatology. 56:S476
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f40c7b45fc0a3efd67e5c1679c70a63
https://doi.org/10.1016/s0168-8278(12)61214-8
https://doi.org/10.1016/s0168-8278(12)61214-8