Výsledky vyhledávání - "K. Yu. Suponitskii"

Analytical Control of Darunavir Tablet Dosage Forms. Part I

Autor: O. N. Glotova, N. L. Shimanovskii, M. S. Goizman, T. E. Popova, G. B. Tikhomirova, K. Yu. Suponitskii, Alexander A. Korlyukov, A. O. Popova, O. A. Zotova

Publikováno v: Pharmaceutical Chemistry Journal. 51:1030-1036

Purposeful development of special methods to be included into pharmacopoeial monographs on the quality of darunavir (DRV) preparations is shown to allow the use of expensive imported standard samples (SSs) for drug analysis to be avoided. Part I of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab7856126f150569a5dacee08d40e380
https://doi.org/10.1007/s11094-018-1734-4

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2-Halobenzoyl chlorides in the synthesis of [1,3,4]thiadiazolo[3,2-a]quinazolin-5-one derivatives

Autor: S. I. Filimonov, P. A. Agat’ev, Angelina S. Danilova, K. Yu. Suponitskii, A. V. Tarasov, R. M. Shlenev

Publikováno v: Russian Journal of Organic Chemistry. 53:1870-1877

New nitro and sulfonamide derivatives of [1,3,4]thiadiazolo[3,2-a]quinazolin-5-one have been synthesized by cyclocondensation of 1,3,4-thiadiazol-2-amines with 2-halobenzoyl chlorides containing electron-withdrawing substituents in positions 3, 4, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bf91215f78e57ae60910f1aa5d51d5f
https://doi.org/10.1134/s1070428017120156

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Synthesis and membrane-protective activity of 4-aminomethyl derivatives of 2,6-diisobornylphenol

Autor: A. V. Kutchin, K. Yu. Suponitskii, Evgeny V. Buravlev, I. Yu. Chukicheva, Oksana G. Shevchenko

Publikováno v: Russian Chemical Bulletin. 66:91-98

A series of 4-aminomethyl derivatives of 2,6-diisobornylphenol containing tertiary and secondary amino groups were synthesized. Their toxicity and the membrane-protective and antioxidant activity were assessed using red blood cells of laboratory mice

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https://doi.org/10.1007/s11172-017-1705-z

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Autor: A. O. Popova, A. A. Kamalova, S. A. Zaitsev, D. L. Shobolov, K. Yu. Suponitskii, M. S. Goizman, Alexander A. Korlyukov, E. V. Degterev, O. A. Zotova, N. L. Shimanovskii

Publikováno v: Pharmaceutical Chemistry Journal. 50:413-418

It is shown that prolongation of patent protection for the antiviral drug darunavir by patenting it again as darunavir ethanolate is illegal. The claims of the successor patent “Pseudopolymorphic forms of a HIV protease inhibitor,” WO 2003106461

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https://doi.org/10.1007/s11094-016-1461-7

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Acid-catalyzed reactions of alloxan with compounds containing an activated alkyl group

Autor: Lyudmila V. Belousova, Evgenii N. Shepelenko, Gennadii S. Borodkin, Danil V. Alexeenko, L. Yu. Ukhin, K. Yu. Suponitskii

Publikováno v: Russian Journal of Organic Chemistry. 52:1026-1031

Condensations of alloxan with 2-methylquinoline, 2,6-dimethyl-5-nitroquinoline, and 1-methylisoquinoline were carried out under acidic conditions. Analogous reactions of alloxan with linear structures containing alkyl groups σ,π-conjugated with C=N

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https://doi.org/10.1134/s1070428016070186

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Molecular structure of 3-OXO-URS-12-EN-28-OIC acid anhydride

Autor: N. I. Medvedeva, A. I. Poptsov, Oxana B. Kazakova, T. V. Lopatina, Alexander N. Lobov, K. Yu. Suponitskii

Publikováno v: Journal of Structural Chemistry. 56:953-958

The molecular structure of 3-oxo-urs-12-en-28-oic acid anhydride is determined. Crystals of C60H90O5 compound (III) are monoclinic, space group С2, at 100 K a = 15.1308(13) A, b = 23.5150(19) A, c = 15.1275(12) A, β = 108.276(2)°. Molecules in the

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https://doi.org/10.1134/s0022476615050194

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Synthesis of unsymmetrical hydroxybenzylphenols from 2-isobornyl-4-methylphenol

Autor: Evgeny V. Buravlev, K. Yu. Suponitskii, A. V. Kutchin, M. A. Elfimova, I. Yu. Chukicheva

Publikováno v: Russian Journal of Organic Chemistry. 51:623-628

2-Hydroxymethyl-6-isobornyl-4-methylphenol was synthesized from 2-isobornyl-4-methylphenol. Reactions of this hydroxymethyl derivative with 2,4- and 2,4-di-tert-butylphenols gave new unsymmetrical hydroxybenzylphenols.

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https://doi.org/10.1134/s1070428015050061

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Physicochemical, Terminological, and Ethical Aspects of the Patenting of Substances and Medicinal Formulations of Abacavir Sulfate

Autor: Alexander A. Korlyukov, K. Yu. Suponitskii, A. A. Kamalova, M. S. Goizman, T. É. Balayants, A. O. Popova, E. V. Degterev, S. A. Zaitsev, S. Kh. Papikyan, A. S. Trifilenkov, A. S. Berlyand, N. L. Shimanovskii

Publikováno v: Pharmaceutical Chemistry Journal. 49:65-72

Using abacavir sulfate substance and medicinal formulations as an example, this being an agent used as an active pharmaceutical substance (APS) protected by a series of patents, we demonstrate that additional patenting has occurred because its physic

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https://doi.org/10.1007/s11094-015-1223-y

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Synthesis of chiral 1,2-diamines from α-pinene and their use in asymmetric nitroaldol reaction

Autor: I. Yu. Chukicheva, Evgeny V. Buravlev, I. A. Dvornikova, K. Yu. Suponitskii, A. V. Kutchin

Publikováno v: Russian Journal of Organic Chemistry. 51:480-492

Chiral diamines with C 1 and C 2 symmetry have been synthesized from 2-hydroxypinan-3-one and tested as ligands in Cu-catalyzed asymmetric nitroaldol reaction of nitromethane with 4-nitrobenzaldehyde.

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https://doi.org/10.1134/s1070428015040041

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Effect of the nature of non-bridging donor atoms on the structure and magnetic properties of binuclear copper(II) complexes with heterocyclic azomethyne ligands

Autor: V. A. Kogan, Ali I. Uraev, Sergey I. Levchenkov, Igor N. Shcherbakov, A. M. Ionov, Alexander A. Zubenko, K. Yu. Suponitskii, L. D. Popov

Publikováno v: Journal of Structural Chemistry. 56:113-120

Pyrazolate bridging binuclear copper(II) complex with a heterocyclic azomethyne ligand (a condensation product of 1,3-diaminopropanol-2 with 1-phenyl-3-methyl-4-formyl-5-mercaptopyrazole) is synthesized and structurally characterized. The structure o

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https://doi.org/10.1134/s0022476615010163

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