Zobrazeno 1 - 10
of 256
pro vyhledávání: '"K. Yu. Suponitskii"'
Autor:
Alexander A. Korlyukov, M. S. Goizman, N. L. Shimanovskii, A. V. Sinel’nikov, A. O. Popova, O. A. Zotova, K. Yu. Suponitskii, I. O. Ryzhkov, M. G. Chernobrovkin
Publikováno v:
Pharmaceutical Chemistry Journal. 53:876-882
Secondary patenting of organic compounds that can undoubtedly be used as active pharmaceutical ingredients (APIs) is discussed. As a rule, such compounds, their synthetic pathways, and potential applications as APIs are patented several years before
Autor:
O. N. Glotova, N. L. Shimanovskii, M. S. Goizman, T. E. Popova, G. B. Tikhomirova, K. Yu. Suponitskii, Alexander A. Korlyukov, A. O. Popova, O. A. Zotova
Publikováno v:
Pharmaceutical Chemistry Journal. 51:1030-1036
Purposeful development of special methods to be included into pharmacopoeial monographs on the quality of darunavir (DRV) preparations is shown to allow the use of expensive imported standard samples (SSs) for drug analysis to be avoided. Part I of t
Autor:
S. I. Filimonov, P. A. Agat’ev, Angelina S. Danilova, K. Yu. Suponitskii, A. V. Tarasov, R. M. Shlenev
Publikováno v:
Russian Journal of Organic Chemistry. 53:1870-1877
New nitro and sulfonamide derivatives of [1,3,4]thiadiazolo[3,2-a]quinazolin-5-one have been synthesized by cyclocondensation of 1,3,4-thiadiazol-2-amines with 2-halobenzoyl chlorides containing electron-withdrawing substituents in positions 3, 4, an
Autor:
A. N. Morozov, L. D. Popov, Sergey I. Levchenkov, Yu. O. Tkacheva, E. A. Raspopova, K. Yu. Suponitskii
Publikováno v:
Russian Journal of General Chemistry. 87:1759-1765
1'-Phthalazinylhydrazone of acetylferrocene (HL) and copper(II) and nickel(II) complexes on its basis [CuL2] and [NiL2] have been synthesized and investigated. The structure of the hydrazine was determined by X-ray diffraction analysis. Quantum-chemi
Autor:
A. V. Kutchin, K. Yu. Suponitskii, Evgeny V. Buravlev, I. Yu. Chukicheva, Oksana G. Shevchenko
Publikováno v:
Russian Chemical Bulletin. 66:91-98
A series of 4-aminomethyl derivatives of 2,6-diisobornylphenol containing tertiary and secondary amino groups were synthesized. Their toxicity and the membrane-protective and antioxidant activity were assessed using red blood cells of laboratory mice
Autor:
A. O. Popova, A. A. Kamalova, S. A. Zaitsev, D. L. Shobolov, K. Yu. Suponitskii, M. S. Goizman, Alexander A. Korlyukov, E. V. Degterev, O. A. Zotova, N. L. Shimanovskii
Publikováno v:
Pharmaceutical Chemistry Journal. 50:413-418
It is shown that prolongation of patent protection for the antiviral drug darunavir by patenting it again as darunavir ethanolate is illegal. The claims of the successor patent “Pseudopolymorphic forms of a HIV protease inhibitor,” WO 2003106461
Autor:
Lyudmila V. Belousova, Evgenii N. Shepelenko, Gennadii S. Borodkin, Danil V. Alexeenko, L. Yu. Ukhin, K. Yu. Suponitskii
Publikováno v:
Russian Journal of Organic Chemistry. 52:1026-1031
Condensations of alloxan with 2-methylquinoline, 2,6-dimethyl-5-nitroquinoline, and 1-methylisoquinoline were carried out under acidic conditions. Analogous reactions of alloxan with linear structures containing alkyl groups σ,π-conjugated with C=N
Autor:
N. I. Medvedeva, A. I. Poptsov, Oxana B. Kazakova, T. V. Lopatina, Alexander N. Lobov, K. Yu. Suponitskii
Publikováno v:
Journal of Structural Chemistry. 56:953-958
The molecular structure of 3-oxo-urs-12-en-28-oic acid anhydride is determined. Crystals of C60H90O5 compound (III) are monoclinic, space group С2, at 100 K a = 15.1308(13) A, b = 23.5150(19) A, c = 15.1275(12) A, β = 108.276(2)°. Molecules in the
Publikováno v:
Russian Journal of Organic Chemistry. 51:623-628
2-Hydroxymethyl-6-isobornyl-4-methylphenol was synthesized from 2-isobornyl-4-methylphenol. Reactions of this hydroxymethyl derivative with 2,4- and 2,4-di-tert-butylphenols gave new unsymmetrical hydroxybenzylphenols.
Autor:
Alexander A. Korlyukov, K. Yu. Suponitskii, A. A. Kamalova, M. S. Goizman, T. É. Balayants, A. O. Popova, E. V. Degterev, S. A. Zaitsev, S. Kh. Papikyan, A. S. Trifilenkov, A. S. Berlyand, N. L. Shimanovskii
Publikováno v:
Pharmaceutical Chemistry Journal. 49:65-72
Using abacavir sulfate substance and medicinal formulations as an example, this being an agent used as an active pharmaceutical substance (APS) protected by a series of patents, we demonstrate that additional patenting has occurred because its physic