Zobrazeno 1 - 10 of 16 pro vyhledávání: '"K. Y. Puong"'
1
Genetic analysis of SCA2, 3 and 17 in idiopathic Parkinson's disease
Autor: S.H. Lim, Yih Yuen, S.W. Lim, R. Pavanni, E. Chua, Meng Cheong Wong, Yi Zhao, I.S. Ng, K. Y. Puong, Eng-King Tan, C.S. Yoon, H.Y. Law
Publikováno v: Neuroscience Letters. 403:11-14
Recent reports of SCA2 and SCA3 patients who presented with levodopa responsive parkinsonism have generated considerable interest as they have implications for genetic testing. It is unclear whether ethnic race alone or founder effects within certain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61ff88cca2c08fbd08d746edfd78929
https://doi.org/10.1016/j.neulet.2006.04.019
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2
PINK1 mutations in sporadic early-onset Parkinson's disease
Autor: Yih Yuen, Louis C.S. Tan, Fung-Peng Woon, K. T. Moe, Deidre A De Silva, K. Puvan, Eng-King Tan, Meng-Cheong Wong, Hui Shen, Dominic Jamora, Kenneth Yew, Esther Lee, R. Pavanni, E. Chua, K. Y. Puong, Yi Zhao
Publikováno v: Movement Disorders. 21:789-793
Pathogenic PINK1 mutations have been described in PARK6-linked Parkinson's disease (PD) patients of Asian origin. However, data on the frequency of PINK1 mutations in sporadic early-onset Parkinson's disease (EOPD) Asian patients are lacking. The obj
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17bfe71906837b24c12ef14dfdc2eaa
https://doi.org/10.1002/mds.20810
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3
Impaired transcriptional upregulation of Parkin promoter variant under oxidative stress and proteasomal inhibition: clinical association
Autor: Yih Yuen, Ping Wing Ng, Jean Woo, Eng-King Tan, Kenneth Yew, K. Y. Puong, Hui Shen, R. Pavanni, Daniel Kam Yin Chan, Meng-Cheong Wong, K. Puvan, Stephanie Fook-Chong, Y. Zhao
Publikováno v: Human Genetics. 118:484-488
We provided data to show that the transcriptional activity of wildtype -258T in the parkin promoter region was significantly higher than the -258G variant in human cell lines. The transcriptional activity of wildtype -258T was significantly increased
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391f63216d55d16e257dae6e58485124
https://doi.org/10.1007/s00439-005-0038-4
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4
Analysis of LRRK2 functional domains in nondominant Parkinson disease
Autor: Yih Yuen, K. Y. Puong, Eng-King Tan, Meng-Cheong Wong, Roland Dominic G. Jamora, Y. Zhao, Matthew J. Farrer, Hui Shen, R. Pavanni, E. Chua, Jianjun Liu, Prasanna R. Kolatkar, Lisa Skipper, Louis C.S. Tan, Carine Bonnard, K. Puvan
Publikováno v: Neurology. 65:1319-1321
A comprehensive sequence analysis of 29 exons that code for the functional domains of LRRK2 in 160 nondominant Parkinson disease (PD) patients was performed. Novel variant screening in a further 470 sporadic PD patients and 630 controls revealed two
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60bafecbfbd908eafb38f1b936deb7ca
https://doi.org/10.1212/01.wnl.0000180517.70572.37
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6
Molecular epidemiology of chikungunya strains in Singapore in 2008
Autor: Kwai-Peng Chan, K. Y. Puong
Publikováno v: Retrovirology, Vol 7, Iss Suppl 1, p P182 (2010)
Retrovirology
Methods Blood samples were inoculated into A. albopictus C6/36 cells and Vero cells. Positive cultures for CHIKV were confirmed by RT-PCR targeting the gene that codes for CHIKV viral envelope protein E2. Viral RNA was extracted from the supernatant
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fce724e9e999cca9e0c62a46a4cffb
https://doi.org/10.1186/1742-4690-7-s1-p182
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7
Case-control study of UCHL1 S18Y variant in Parkinson's disease
Autor: Kathiravelu Puvan, Stephanie Fook-Chong, Yih Yuen, Eng-King Tan, R. Pavanni, Hui Shen, Y. Zhao, E. Chua, K. Y. Puong, Meng-Cheong Wong
Publikováno v: Movement disorders : official journal of the Movement Disorder Society. 21(10)
A recent meta-analysis observed a greater significant inverse association of the ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y variant with Parkinson's disease (PD) for Asian (predominantly Japanese) populations compared with Caucasian populat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be38668dbd037b5abef26751f2a2952
https://pubmed.ncbi.nlm.nih.gov/16941465
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9
The G2019S LRRK2 mutation is uncommon in an Asian cohort of Parkinson's disease patients
Autor: Eng-King Tan, K. Yew, K. Y. Puong, Yuen Yih, Y. Zhao, Lisa Skipper, Hui Shen, Louis C.S. Tan, R. Pavanni, Roland Dominic G. Jamora, Matthew J. Farrer, E. Chua, Meng-Cheong Wong, K. Puvan, Jianjun Liu
Publikováno v: Neuroscience letters. 384(3)
A common heterozygous leucine-rich repeat kinase 2 (LRRK2) mutation 6055GA transition (G2019S) accounts for about 3-7% of familial Parkinson's disease (PD) and 1-1.6% sporadic PD in a number of European populations. To determine the prevalence of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4691c62c57ca295df891511b6c79cb1a
https://pubmed.ncbi.nlm.nih.gov/15955629
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10
Fragile X premutation alleles in SCA, ET, and parkinsonism in an Asian cohort
Autor: Ling Ling Chan, Hai-Yang Law, Eng-King Tan, Meng-Cheong Wong, M.L. Teoh, K. Y. Puong, I. S. Ng, V. R. Chandran, K. Yew, C. Tan, R. Pavanni, Yi Zhao, Hui Shen, Y. Yih
Publikováno v: Neurology. 63(2)
Among 367 subjects, the authors analyzed 167 patients with essential tremor, sporadic progressive cerebellar ataxia, multiple-system atrophy, and atypical parkinsonism and 200 healthy control subjects for FMR1 premutation alleles. None of the subject
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ba7ace65f9f6cde56d3a347eb6a576
https://pubmed.ncbi.nlm.nih.gov/15277639
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