Zobrazeno 1 - 10
of 20
pro vyhledávání: '"K. Wing Leung"'
Autor:
Janet Y.M. Ho, Ada W.S. Yip, K. Wing Leung, Ran Duan, J.K.H. Cheung, Karl Wah Keung Tsim, Karen K.L. Ho, Zack C.F. Wong
Publikováno v:
Drug Testing and Analysis. 10:977-983
The aim of this study is to reveal the habits of drug abusers in hair samples from drug rehabilitation units in Hong Kong. With the application of liquid chromatography-tandem mass spectrometry (LC-MS/MS) technology, a total of 1771 hair samples were
Autor:
Gallant K.L. Chan, Ava J.Y. Guo, Wilson K.W. Luk, Roy Chi Yan Choi, Karl Wah Keung Tsim, K. Wing Leung, Vicky Ping Chen, Wallace K.B. Chan
Publikováno v:
Journal of Biological Chemistry. 286:32948-32961
Acetylcholinesterase (AChE) anchors onto cell membranes by a transmembrane protein PRiMA (proline-rich membrane anchor) as a tetrameric form in vertebrate brain. The assembly of AChE tetramer with PRiMA requires the C-terminal “t-peptide” in AChE
Autor:
Jean Massoulié, Gallant K.L. Chan, Heidi Qunhui Xie, K. Wing Leung, Vicky Ping Chen, Roy Chi Yan Choi, Suzanne Bon, Wallace K.B. Chan, Karl Wah Keung Tsim
Publikováno v:
Journal of Biological Chemistry. 285:27265-27278
Acetylcholinesterase (AChE) is anchored onto cell membranes by the transmembrane protein PRiMA (proline-rich membrane anchor) as a tetrameric globular form that is prominently expressed in vertebrate brain. In parallel, the PRiMA-linked tetrameric bu
Autor:
Roy Chi Yan Choi, Karl Wah Keung Tsim, Jean Massoulié, Kevin Y. Zhu, Dong Liang, Vicky Ping Chen, Heidi Qunhui Xie, Wallace K.B. Chan, K. Wing Leung
Publikováno v:
Journal of Biological Chemistry. 285:11537-11546
In the mammalian brain, acetylcholinesterase (AChE) is anchored in cell membranes by a transmembrane protein PRiMA (proline-rich membrane anchor). We present evidence that at least part of the PRiMA-linked AChE is integrated in membrane microdomains
Autor:
Ken Y.Z. Zheng, Vicky Ping Chen, Ava J.Y. Guo, K. Wing Leung, Karl Wah Keung Tsim, Roy Chi Yan Choi, Heidi Qunhui Xie, Judy T T Zhu, David T W Lau, Ka Wai Mok, Kevin Y. Zhu, Cathy W. C. Bi
Publikováno v:
Journal of Molecular Neuroscience. 40:40-46
Acetylcholinesterase (AChE) is well known to process different molecular forms via the distinct interacting partners. Proline-rich membrane anchor (PRiMA)-linked tetrameric globular AChE (G4 AChE) is mainly found in the vertebrate brain; however, rec
Autor:
Karl Wah Keung Tsim, Roy Chi Yan Choi, Heidi Qunhui Xie, Glanice K.Y. Chu, K. Wing Leung, Mokka K.W. Mok, Vicky Ping Chen
Publikováno v:
FEBS Journal. 276:3031-3042
The expression and localization of the proline-rich membrane anchor (PRiMA), an anchoring protein of tetrameric globular form acetylcholinesterase (G(4) AChE), were studied at vertebrate neuromuscular junctions. Both muscle and motor neuron contribut
Autor:
Heidi Qunhui Xie, Karl Wah Keung Tsim, Faye T.C. Lau, Roy Chi Yan Choi, Lois S. Liu, Vicky Ping Chen, K. Wing Leung
Publikováno v:
Chemico-Biological Interactions. 175:79-82
The tetrameric globular form of acetylcholinesterase (G 4 AChE) is present and precisely controlled in muscles. The assembly and membrane targeting of G 4 AChE are directed by a proline-rich membrane anchor (PRiMA). It has been demonstrated that in m
Autor:
Karen K.L. Ho, Ran Duan, Zack C.F. Wong, Stanley P.H. Ip, Ada W.S. Yip, Jenny S.C. Ng, Winki Y.Y. Ng, KY Zhu, K. Wing Leung, Janet Y.M. Ho, Karl Wah Keung Tsim
Publikováno v:
Forensic science international. 259
Ketamine is one of the most frequent abused drugs in Hong Kong and South-East Asia, and the cases of ketamine abused have been reported worldwide. Hair has been commonly used as a specimen for the proof of chronic drug abused because of its non-invas
Autor:
Winki Y.Y. Ng, Karl Wah Keung Tsim, Annie K.L. Ting, Kevin Y. Zhu, Roy Chi Yan Choi, K. Wing Leung, David T W Lau, Tina T. X. Dong, Tiejie Wang, Zack C.F. Wong
Publikováno v:
Analytical and bioanalytical chemistry. 402(9)
A microfluidic chip based nano-HPLC coupled to tandem mass spectrometry (nano-HPLC-Chip-MS/MS) has been developed for simultaneous measurement of abused drugs and metabolites: cocaine, benzoylecgonine, cocaethylene, norcocaine, morphine, codeine, 6-a
Autor:
Vicky P, Chen, Roy C Y, Choi, Wallace K B, Chan, K Wing, Leung, Ava J Y, Guo, Gallant K L, Chan, Wilson K W, Luk, Karl W K, Tsim
Publikováno v:
The Journal of biological chemistry. 286(38)
Acetylcholinesterase (AChE) anchors onto cell membranes by a transmembrane protein PRiMA (proline-rich membrane anchor) as a tetrameric form in vertebrate brain. The assembly of AChE tetramer with PRiMA requires the C-terminal "t-peptide" in AChE cat