Zobrazeno 1 - 10
of 19
pro vyhledávání: '"K. W. A. Bang"'
Autor:
Erica Y. Scott, Nickie Safarian, Daniela Lozano Casasbuenas, Michael Dryden, Teodora Tockovska, Shawar Ali, Jiaxi Peng, Emerson Daniele, Isabel Nie Xin Lim, K. W. Annie Bang, Shreejoy Tripathy, Scott A. Yuzwa, Aaron R. Wheeler, Maryam Faiz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Astrocytes, a type of glial cell in the central nervous system (CNS), adopt diverse states in response to injury that are influenced by their location relative to the insult. Here, we describe a platform for spatially resolved, single-cell t
Externí odkaz:
https://doaj.org/article/92b2bf20c25e4738800225acc0ed64c1
Autor:
Jessica M. Livingston, Tina T. Lee, Tom Enbar, Emerson Daniele, Clara M. Phillips, Alexandra Krassikova, K. W. Annie Bang, Ines Kortebi, Brennan W. Donville, Omadyor S. Ibragimov, Nadia Sachewsky, Daniela Lozano Casasbuenas, Arman Olfat, Cindi M. Morshead
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 663 (2024)
Stroke is the leading cause of adult disability worldwide. The majority of stroke survivors are left with devastating functional impairments for which few treatment options exist. Recently, a number of studies have used ectopic expression of transcri
Externí odkaz:
https://doaj.org/article/bd79272862d64e0c9a0bb4df21383a27
Autor:
Judith Elbaz, Mira C. Puri, Maryam Faiz, K. W. Annie Bang, Lena Nguyen, Bar Makovoz, Marina Gertsenstein, Samer M. I. Hussein, Peter W. Zandstra, Laurent Briollais, Nika Shakiba, Andras Nagy
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Revealing the molecular events associated with reprogramming different somatic cell types to pluripotency is critical for understanding the characteristics of induced pluripotent stem cell (iPSC) therapeutic derivatives. Inducible reprogramming facto
Autor:
Hilary Christensen, Emily C. Reddy, Hong Wang, Eileen M. McMillan-Ward, Sara J. Israels, Margaret L. Rand, K. W. Annie Bang
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Background Upon platelet activation, a subpopulation of procoagulant platelets is formed, characterized by the exposure of the anionic aminophospholipid phosphatidylserine (PS) on the surface membrane. Objective To evaluate procoagulant PS-exposing p
Autor:
Fina Lovren, Praphulla C. Shukla, A. Creighton, Krishna K. Singh, Adrian Quan, Subodh Verma, Yi Pan, Howard Leong-Poi, Nandini Gupta, Hwee Teoh, Mohammed Al-Omran, K. W. Annie Bang
Publikováno v:
Gene Therapy. 20:51-61
Sepsis-related complications and mortality remain a major clinical problem. Increased cell death and unresolved cellular repair have been implicated as key upstream mediators of sepsis-induced organ dysfunction and death. We hypothesised that gene th
Autor:
Imane Azzouzi, Oliver Speer, Margaret L. Rand, Sabine Kroiss, Jeannine Winkler, Markus Schmugge, K. W. Annie Bang
Publikováno v:
British Journal of Haematology. 156:508-515
SummaryTo evaluate the role of intravenous immunoglobulin (IVIg) in plateletapoptosis in paediatric immune thrombocytopenia, we investigated theplatelets of 20 paediatric patients with acute immune thrombocytopenia(ITP), before and after IVIg treatme
Autor:
Emil H. Schemitsch, John Freedman, Masaki Nakane, Rad Zdero, Michael Blankstein, Robin R. Richards, Osamu Kajikawa, David Bell, K W Annie Bang, Robert J Byrick
Publikováno v:
The Journal of Bone and Joint Surgery-American Volume. 92:149-161
Background: The objective of this study was to assess the role of pulmonary fat embolism caused by intramedullary pressurization of the femoral canal in the development of acute lung injury in the setting of acute hemorrhagic shock and resuscitation.
Autor:
Milan Gupta, Lawrence Chan, John Freedman, Paul E. Szmitko, Vivian Vu, Haibo Zhang, Adrian Quan, Hwee Teoh, Fina Lovren, Subodh Verma, Gary Sweeney, K. W. Annie Bang, Jack J. Haitsma, Guilin Wang, Mark D. Peterson, Mohammed Al-Omran, Chao-Hung Wang
Publikováno v:
Teoh, H, Quan, A, Bang, K W A, Wang, G, Lovren, F, Vu, V, Haitsma, J J, Szmitko, P E, Al-Omran, M, Wang, C H, Gupta, M, Peterson, M D, Zhang, H, Chan, L, Freedman, J, Sweeney, G & Verma, S 2008, ' Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality ', American Journal of Physiology-Endocrinology and Metabolism, vol. 295, no. 3, pp. E658-E664 . https://doi.org/10.1152/ajpendo.90384.2008
American Journal of Physiology-Endocrinology and Metabolism, 295(3), E658-E664
American Journal of Physiology-Endocrinology and Metabolism, 295(3), E658-E664
Sepsis is a multifactorial, and often fatal, disorder typically characterized by widespread inflammation and immune activation with resultant endothelial activation. In the present study, we postulated that the adipokine adiponectin serves as a criti
Autor:
Marian A. Packham, K. W. A. Bang, Jane E. Freedman, R. Leung, Adam Gwozdz, Margaret L. Rand, Hong Wang
Publikováno v:
Journal of Thrombosis and Haemostasis. 5:560-570
Background Activated platelets express a procoagulant surface when the asymmetric distribution of membrane phospholipids is scrambled, leading to phosphatidylserine (PS) exposure. PS expression, associated with apoptosis in nucleated cells, would be
Autor:
Andrew R. Crow, Heyu Ni, John Freedman, Alan H. Lazarus, Edwin R. Speck, Michael Kim, John W. Semple, Rukhsana Aslam, Frederick P. Nestel, K. W. Annie Bang
Publikováno v:
Blood. 107:637-641
Toll-like receptors (TLRs) play a critical role in stimulating innate immunity by recognizing pathogen-associated molecular patterns (PAMPs) on invading microorganisms. Platelets also play a role in innate immunity, and we studied whether they expres