Geriatric assessment and intervention in older vulnerable patients undergoing surgery for colorectal cancer: a protocol for a randomised controlled trial (GEPOC trial)

Autor: Troels G. Dolin, Marta Mikkelsen, Henrik L. Jakobsen, Tyge Nordentoft, Trine S. Pedersen, Anders Vinther, Bo Zerahn, Kirsten K. Vistisen, Charlotte Suetta, Dorte Nielsen, Julia S. Johansen, Cecilia M. Lund

Publikováno v: BMC Geriatrics, Vol 21, Iss 1, Pp 1-10 (2021)

Abstract Background The incidence of colorectal cancer (CRC) increases with age. Older patients are a heterogeneous group ranging from fit to frail with various comorbidities. Frail older patients with CRC are at increased risk of negative outcomes a

Externí odkaz: https://doaj.org/article/47e0afd903de43f0b05aae079e0163d2

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Bevacizumab plus chemotherapy continued beyond first progression in patients with metastatic colorectal cancer previously treated with bevacizumab plus chemotherapy : ML18147 study KRAS subgroup findings

Autor: S. Kubicka, R. Greil, T. André, J. Bennouna, J. Sastre, E. Van Cutsem, R. von Moos, P. Österlund, I. Reyes-Rivera, T. Müller, M. Makrutzki, D. Arnold, J. Andel, P. Balcke, B. Benedicic, W. Eisterer, M. Fridrik, B. Jagdt, F. Keil, A. Kretschmer, P. Krippl, H. Oexle, M. Pecherstorfer, H. Samonigg, M. Schmid, J. Thaler, C. Tinchon, H. Weiss, J. Arts, M. De Man, G. Demolin, J. Janssens, M. Polus, B. Benczikova, B. Melichar, J. Prausova, P. Vitek, F.Z. Andersen, B.B. Jensen, N. Keldsen, K. Østerlind, K. Vistisen, A. Elme, A. Magi, K. Ojamaa, R. Ristamäki, T. Salminen, M. Ben Abdelghani, O. Bouche, C. Borg, K. Bouhier-Leporrier, G. Breysacher, L. Chone, M.-C. Clavero Fabri, G. Deplanque, F. Desseigne, L.-M. Dourthe, J. Ezenfis, R. Faroux, E. François, C. Garnier, M.-H. Gaspard, M. Hebbar, J.F. Illory, M.-C. Kaminsky, T. Lecomte, J.-L. Legoux, B. Levache, C. Lobry, J.-P. Lotz, M. Mabro, S. Manet-Lacombe, S. Manfredi, T. Matysiak Budnik, L. Miglianico, L. Mineur, I. Moullet, H. Naman, P. Nouyrigat, S. Oziel-Taieb, H. Perrier, D. Pezet, J. Philip, V. Pottier, M. Porneuf, M. Ramdani, D. Re, Y. Rinaldi, D. Spaeth, J. Taieb, E. Terrebonne, P. Texereau, A. Thirot Bidault, C. Tournigand, N. Tubiana-Mathieu, J.-M. Vantelon, F. Viret, M. Ychou, M. Bangerter, M.E. Bertram, B. Bohnsteen, L. Brinkmann, K. Caca, C. Constantin, H.-J. Cordes, G. Dietrich, J. Eggert, E. Engel, J. Fahlke, H. Fensterer, A. Florschütz, G. Folprecht, H. Forstbauer, W. Freier, M. Freund, N. Frickhofen, E. Gäbele, M. Geißler, F. Gieseler, T. Göhler, U. Graeven, M. Groschek, M. Grundeis, U. Hacker, V. Hagen, H.F. Hebart, S. Hegewisch-Becker, M. Heike, T. Herrmann, B. Hildebrandt, H.-G. Höffkes, G. Hübner, J. Hübner, E. Kettner, M. Kneba, J.W. Kohnke, G. Kojouharoff, C. König, A. Kretzschmar, H. Kröning, K. Kürner, F. Lammert, C. Lerchenmüller, A. Lück, J. Meiler, H.-G. Mergenthaler, L. Müller, C. Müller-Naendrup, A. Nusch, J. Papke, R. Porschen, J. Rädle, C. Reddemann, K. Ridwelski, J. Riera-Knorrenschild, J. Rudi, A. Schmalenberger, C.-C. Schimanski, F. Schlegel, C. Schlichting, P. Schmidt, W. Schmiegel, S. Schmitz, H. Schulze-Bergkamen, I. Schwaner, A. Schwarzer, M. Schwerdtfeger, J. Selbach, M. Sieber, J. Siebler, P. Staib, M. Stauch, C.-C. Steffens, P. Stübs, J. Tischendorf, T. Trarbach, D. Tummes, A.-R. Valdix, A. Vogel, G.P.L. Von Wichert, M. Walther, W. Welslau, G. Wilhelm, H. Wobster, T. Wolf, N. Zeigenhagen, B. Zomorodbaksch, E. Batman, H.J. Bloemendal, D.F.S. Kehrer, T. Guren, G. Indrebø, C. Kersten, H. Soerbye, M. Fragoso, R. Fragoso, J.C. Mellidez, A. Sa, A. Aljobran, T. Darwish, V. Alonso-Orduna, J. Aparicio, E. Aranda, C. Bosch, A. Galan-Brotons, I. Busquier Hernandez, J.C. Camara, J.M. Campos Cervera, C. Carlos Garcia Giron, P.M. Del Prado, O. Donnay, P. Escudero, E. Falco, J. Gallego Plazas, P. Garcia Alfonso, E. Gonzalez Flores, C. Gravalos, R. Guardeno, A. Juárez, A. Lopez Ladron, F. Losa Gaspa, J. MªVicent Vergé, E. Marcuello Gaspar, B. Massuti Sureda, J. Molina, I.C. Montero, A.L. Muñoa, M.B. Naranjo, M.J. Oruezabal Moreno, V. Pachón Olmos, C. Pericay, J.J. Reina Zoilo, F. Rivera, A. Ruiz Casado, M.J. Safont, A. Salud Salvia, M. Tobena, J.C. Toral, V. Valenti, M. Valladares Ayerbes, J.M. Vieitez, R. Vera, A. Berglund, E. Fernebro, V. Hess-Umbricht, M. Pless, R. Popescu, R. Winterhalder

ML18147 evaluated continued bevacizumab with second-line chemotherapy for patients with metastatic colorectal cancer (mCRC) progressing after the standard first-line bevacizumab-containing therapy.Evaluating outcomes according to tumor Kirsten rat sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c523a56f9351b43c7684d54c3124cffe
https://www.ncbi.nlm.nih.gov/pubmed/23852309

Use of tumor lines with selectable markers in assessing the effect on experimental metastases of combination chemotherapy with alkylating agents

Autor: B E, Miller, L, Delmonico, K, Vistisen, F R, Miller

Publikováno v: Clinicalexperimental metastasis. 16(5)

High-dose chemotherapy with a 3-day regimen of cyclophosphamide, cisplatin, and carmustine was used to treat mice bearing experimental lung metastases of mammary tumor cell lines with selectable markers (lines 66cl4 and 4TO7). Cloning of lung cells a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::81d050d8a2dca2ebcef9b20c97b11ff8
https://pubmed.ncbi.nlm.nih.gov/10091943

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.