Výsledky vyhledávání - "K. Verlinden"

Resisting resistance: is there a solution for malaria?

Autor: Lyn-Marie Birkholtz, Abraham I. Louw, Bianca K. Verlinden

Publikováno v: Expert Opinion on Drug Discovery. 11:395-406

Currently, widely used antimalarial drugs have a limited clinical lifespan due to parasite resistance development. With resistance continuously rising, antimalarial drug discovery requires strategies to decrease the time of delivering a new antimalar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b238b393acfb861be1da151a612c8732
https://doi.org/10.1517/17460441.2016.1154037

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SPECIFIC MAPPING OF DISEASE RESISTANCE GENES IN TETRAPLOID CUT ROSES

Autor: C.F.S. Koning-Boucoiran, O. Dolstra, C.G. van der Linden, J. van der Schoot, V.W. Gitonga, K. Verlinden, C.A. Maliepaard, F.A. Krens

Publikováno v: Acta Horticulturae 2009 (2009) 836
Acta Horticulturae, 2009(836), 137-142

Control of fungal diseases is a major constraint of cut-rose cultivation in greenhouses and in transportation around the world. Therefore, development of resistant cultivars is a promising way to reduce the use of chemicals required for controlling t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3740a07a49d3c5f7fd21a62f97f06506
https://doi.org/10.17660/actahortic.2009.836.19

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Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites

Autor: Lyn-Marie Birkholtz, Bianca K. Verlinden, Kiplin R. Guy, Riëtte van Biljon, Ethan Besaans, Marna de Beer, Patrick M. Woster, Jandeli Niemand, Janette Reader, Timothy J. Egan, Warren A. Andayi, Boobalan Pachaiyappan

Publikováno v: Bioorganicmedicinal chemistry. 23(16)

A new series of potent potent aryl/alkylated (bis)urea- and (bis)thiourea polyamine analogues were synthesized and evaluated in vitro for their antiplasmodial activity. Altering the carbon backbone and terminal substituents increased the potency of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714eb26029c7af4572418de6052e1783
https://pubmed.ncbi.nlm.nih.gov/25684422

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Anthracene-polyamine conjugates inhibit in vitro proliferation of intraerythrocytic plasmodium falciparum parasites

Autor: Lyn-Marie Birkholtz, Janette Reader, Kiaran Kirk, Otto Phanstiel, Bianca K. Verlinden, Annette Kaiser, Annie M. Joubert, Abraham I. Louw, Jandeli Niemand, Pieter Buys Burger

Anthracene-polyamine conjugates inhibit the in vitro proliferation of the intraerythrocytic human malaria parasite Plasmodium falciparum , with 50% inhibitory concentrations (IC 50 s) in the nM to μM range. The compounds are taken up into the intrae

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4519618aef553921e514204d5dfb318b
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84877866711

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The mode of inheritance in tetraploid cut roses

Autor: Chris Maliepaard, J.R. van der Schoot, Carole F. S. Koning-Boucoiran, Virginia W. Gitonga, K. Verlinden, C.G. van der Linden, Frans A. Krens, Zhe Yan, G. E. Uenk, Oene Dolstra, Marinus J. M. Smulders

Publikováno v: Theoretical and Applied Genetics 125 (2012) 3
TAG. Theoretical and Applied Genetics. Theoretische Und Angewandte Genetik
Theoretical and Applied Genetics, 125(3), 591-607

Tetraploid hybrid tea roses (Rosa hybrida) represent most of the commercial cultivars of cut roses and form the basis for breeding programmes. Due to intensive interspecific hybridizations, modern cut roses are complex tetraploids for which the mode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e7724551e6d68e6129904f47d02df4
https://research.wur.nl/en/publications/the-mode-of-inheritance-in-tetraploid-cut-roses

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A stereologic evaluation of glucagon-like peptide-1 (GLP-1) mucosal cells in the small intestine of the developing pig

Autor: Stanislas U. Sys, C. Van Ginneken, A. Weyns, F Van Meir, K Verlinden

Publikováno v: Anatomy and embryology

Studies that investigate possible developmental changes in gastrointestinal hormones in the pig are sparse and contradictory. Therefore, a quantitative morphological study using stereologic methods on paraffin sections of the different small intestin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4a89a5849630ebb979a8016c6598f7
https://pubmed.ncbi.nlm.nih.gov/12021917

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