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Akademický článek
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Publikováno v:
Development. 127:2883-2895
We used transgenesis to explore the requirement for downregulation of hepatocyte nuclear factor 6 (HNF6) expression in the assembly, differentiation, and function of pancreatic islets. In vivo, HNF6 expression becomes downregulated in pancreatic endo
Autor:
William L. Castleman, Jean Nicolas Vauthey, U Ettlin, H Loetscher, Edward M. Copeland, B Wipf, Lyle L. Moldawer, S F Lowry, M B Welborn, W Lesslauer, K Van Zee, M. A. Rogy, Atsushi Kaibara, Jeffrey H. Pruitt, J S Kenney, Paul D. Edwards, D Stüber
Publikováno v:
The Journal of Experimental Medicine
Tumor necrosis factor (TNF) is a potentially useful adjunct to anticancer therapies. However, the clinical utility of TNF has been limited by generalized toxicity and hypotension. Recently, studies have begun to dissect the individual proinflammatory
Publikováno v:
Plant Physiology. 108:1233-1239
An interval on barley (Hordeum vulgare L.) chromosome 7 accounting for significant quantitative trait locus effects for winter hardiness were detected in a winter (Dicktoo) x spring (Morex) barley population (P.M. Hayes, T. Blake, T.H.H. Chen, S. Tra
Publikováno v:
The Journal of Cell Biology
A cytoplasmically anchored mutant SV40 T antigen, FS T antigen, was shown previously to interfere specifically with the nuclear import of a heterologous nuclear protein, adenovirus 5 fiber protein, in cultured monkey cells (Schneider, J., C. Schindew
Publikováno v:
Molecular and Cellular Biology. 11:5137-5146
Simian virus 40 T antigen is specifically targeted to the nucleus by the signal Pro-Lys-Lys-128-Lys-Arg-Lys-Val. We have previously described the isolation of a simian virus 40 T-antigen mutant, 676FS, which retains a wild-type nuclear localization s
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 23:569-569
The majority of studies on depression among cancer survivors report means or percentages which obscure the heterogeneity of women's responses to cancer. Trajectory analysis provides a more nuanced picture of different patterns of response. Purpose: T
Publikováno v:
The Breast. 21:S17
Publikováno v:
Shock, Sepsis, and Organ Failure ISBN: 9783540553397
Therapies that can reduce the morbidity and mortality of Gram negative septic shock offer great potential for treatment of the critically-ill patient. Septic shock secondary to Gram negative bacteremia or endotoxemia is characterized by hemodynamic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5e06324fd31f5431c468a6792376feb
https://doi.org/10.1007/978-3-642-77420-1_2
https://doi.org/10.1007/978-3-642-77420-1_2