Cauterization as a Simple Method for Regeneration Studies in the Zebrafish Heart

Autor: Papa K. Van Dyck, Natasha Hockaden, Emma C. Nelson, Alyssa R. Koch, Kamil L. Hester, Neil Pillai, Gabrielle C. Coffing, Alan R. Burns, Pascal J. Lafontant

Publikováno v: Journal of Cardiovascular Development and Disease, Vol 7, Iss 4, p 41 (2020)

In the last two decades, the zebrafish has emerged as an important model species for heart regeneration studies. Various approaches to model loss of cardiac myocytes and myocardial infarction in the zebrafish have been devised, and have included rese

Externí odkaz: https://doaj.org/article/8d0d8612c926490991912257cdf59ff2

Sputum RNA signature in allergic asthmatics following allergen bronchoprovocation test

Autor: Veronica M. Rivas, Vladislav A. Malkov, Catherine Tribouley, Rob Zuiker, J. Diderik Boot, Zuzana Diamant, Marcella Ruddy, Adam F. Cohen, K Van Dyck, I De Lepeleire, Jacobus Burggraaf

Publikováno v: European Clinical Respiratory Journal, Vol 3, Iss 0, Pp 1-17 (2016)
European Clinical Respiratory Journal; Vol 3 (2016)
European Clinical Respiratory Journal
European clinical respiratory journal, 3:31324. Taylor & Francis Group

Background : Inhaled allergen challenge is a validated disease model of allergic asthma offering useful pharmacodynamic assessment of pharmacotherapeutic effects in a limited number of subjects. Objectives : To evaluate whether an RNA signature can b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213626b4aa3160c6117f514ff18183a7
http://www.ecrj.net/index.php/ecrj/article/view/31324/47811

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Effect of the Cathepsin K Inhibitor Odanacatib on Bone Resorption Biomarkers in Healthy Postmenopausal Women: Two Double-Blind, Randomized, Placebo-Controlled Phase I Studies

Autor: K Van Dyck, Boyd B. Scott, M De Decker, Stefan Zajic, Maria Gutierrez, Q Liu, Keith Gottesdiener, Deborah Panebianco, Deborah L. Miller, L Liu, Julie A. Stone, Le T. Duong, Bo Jin, SA Stoch, John A. Wagner

Publikováno v: Clinical Pharmacology & Therapeutics. 86:175-182

Inhibition of cathepsin K (CatK) is a potential new treatment for osteoporosis. In two double-blind, randomized, placebo-controlled phase I studies, postmenopausal female subjects received odanacatib (ODN), an orally active, potent, and selective Cat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa3e5822be371fe66a22a34413316a7
https://doi.org/10.1038/clpt.2009.60

Gastrointestinal Permeation Enhancers Beyond Sodium Caprate and SNAC ‐ What is Coming Next?

Autor: Bohley, Marilena¹ (AUTHOR), Leroux, Jean‐Christophe¹ (AUTHOR) jleroux@ethz.ch

Publikováno v: Advanced Science. 9/4/2024, Vol. 11 Issue 33, p1-18. 18p.