Detecting inappropriate total duration of antimicrobial therapy using semi-automated surveillance

Autor: Annemieke K. van den Broek, Jara R. de la Court, Thomas Groot, Reinier M. van Hest, Caroline E. Visser, Kim C. E. Sigaloff, Rogier P. Schade, Jan M. Prins

Publikováno v: Antimicrobial Resistance and Infection Control, Vol 11, Iss 1, Pp 1-9 (2022)

Abstract Objectives Evaluation of the appropriateness of the duration of antimicrobial treatment is a cornerstone of antibiotic stewardship programs, but it is time-consuming. Furthermore, it is often restricted to antibiotics prescribed during hospi

Externí odkaz: https://doaj.org/article/e6807a4ff13e49bdbeba4c120aecc545

Systematic review: the bioavailability of orally administered antibiotics during the initial phase of a systemic infection in non-ICU patients

Autor: Annemieke K. van den Broek, Jan M. Prins, Caroline E. Visser, Reinier M. van Hest

Publikováno v: BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-11 (2021)

Abstract Background The systemic response to an infection might influence the pharmacokinetics of antibiotics. To evaluate the desired possibility of an earlier (

Externí odkaz: https://doaj.org/article/5c35fee6a10f46cdb023fd18c93b8517

Compression of the optic chiasm is associated with reduced photoentrainment of the central biological clock

Autor: Tessel M Boertien, Eus J W Van Someren, Adriaan D Coumou, Annemieke K van den Broek, Jet H Klunder, Wing-Yi Wong, Adrienne E van der Hoeven, Madeleine L Drent, Johannes A Romijn, Eric Fliers, Peter H Bisschop

Publikováno v: Boertien, T M, van Someren, E J W, Coumou, A D, van den Broek, A K, Klunder, J H, Wong, W-Y, van der Hoeven, A E, Drent, M L, Romijn, J A, Fliers, E & Bisschop, P H 2022, ' Compression of the optic chiasm is associated with reduced photoentrainment of the central biological clock ', European Journal of Endocrinology, vol. 187, no. 6, pp. 809-821 . https://doi.org/10.1530/EJE-22-0527
European Journal of Endocrinology, 187(6), 809-821. BioScientifica Ltd.
European Journal of Endocrinology, 187, 809-821. European Federation of Endocrine Societies
Boertien, T M, Van Someren, E J W, Coumou, A D, van den Broek, A K, Klunder, J H, Wong, W Y, van der Hoeven, A E, Drent, M L, Romijn, J A, Fliers, E & Bisschop, P H 2022, ' Compression of the optic chiasm is associated with reduced photoentrainment of the central biological clock ', European Journal of Endocrinology, vol. 187, no. 6, pp. 809-821 . https://doi.org/10.1530/EJE-22-0527

Objective Pituitary tumours that compress the optic chiasm are associated with long-term alterations in sleep–wake rhythm. This may result from damage to intrinsically photosensitive retinal ganglion cells (ipRGCs) projecting from the retina to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4987dea0161d60d7bb11cb2d22b2064b
https://hdl.handle.net/1871.1/84642ca9-cd2b-4159-8243-02e02abcb6da

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Clinical Pharmacokinetics of Gentamicin in Various Patient Populations and Consequences for Optimal Dosing for Gram-Negative Infections: An Updated Review

Autor: Caspar J. Hodiamont, Annemieke K. van den Broek, Suzanne L. de Vroom, Jan M. Prins, Ron A. A. Mathôt, Reinier M. van Hest

Publikováno v: Hodiamont, C J, van den Broek, A K, de Vroom, S L, Prins, J M, Mathôt, R A A & van Hest, R M 2022, ' Clinical Pharmacokinetics of Gentamicin in Various Patient Populations and Consequences for Optimal Dosing for Gram-Negative Infections : An Updated Review ', Clinical Pharmacokinetics, vol. 61, no. 8, pp. 1075-1094 . https://doi.org/10.1007/s40262-022-01143-0

Gentamicin is an aminoglycoside antibiotic with a small therapeutic window that is currently used primarily as part of short-term empirical combination therapy. Gentamicin dosing schemes still need refinement, especially for subpopulations where phar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbcfa845530856c1265065af410dc498
https://pubmed.ncbi.nlm.nih.gov/35754071