Zobrazeno 1 - 6
of 6
pro vyhledávání: '"K. V. Sukhoverkov"'
Publikováno v:
Russian Journal of Physical Chemistry B. 12:1193-1204
A new method for the synthesis of guest–host inclusion complex of moxifloxacin (MF) with 2-hydroxypropyl-β-cyclodextrin (HPCD) by supercritical fluid technology in the rapid expansion of supercritical solutions (RESS) mode was suggested for develo
Autor:
I.M. Deygen, Denis E. Presnov, K. V. Sukhoverkov, Alexey M. Egorov, Elena V. Kudryashova, A. M. Vorobei, O. O. Parenago, O. I. Pokrovskiy
Publikováno v:
Russian Journal of Physical Chemistry B. 11:1153-1162
Supercritical antisolvent (SAS) precipitation is employed for micronization of moxifloxacin (MF), an antibiotic from the fluoroquinolone group, to develop new dosage forms of MF. With this technique, we produced, in a controllable fashion, MF particl
Autor:
L. Yu. Filatova, O. O. Parenago, L. I. Krotova, Elena V. Kudryashova, K.B. Ustinovich, Natalia L. Klyachko, O. I. Pokrovskiy, K. V. Sukhoverkov, Vladimir K. Popov, I.M. Deygen, A. M. Vorobei, E. N. Antonov, A. G. Dunaev, Alexey M. Egorov
Publikováno v:
Russian Journal of Physical Chemistry B. 10:1201-1210
The process of micronization of levofloxacin (LF, an antibacterial agent of the fluoroquinolone group) by the supercritical antisolvent precipitation technique (SAS) was investigated. It was shown that LF particles of different sizes (from 1 to 10 μ
Publikováno v:
Moscow University Chemistry Bulletin. 71:122-126
The ChitoPEGylation method, which is a novel approach to regulating the catalytic properties of enzymes that is based on the formation of a covalent conjugate of an enzyme with branched copolymers of chitosan, has been developed. The efficiency of th
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 8:252-259
A new approach to the regulation of catalytic properties of medically relevant enzymes has been proposed using the novel recombinant preparation of Lasparaginase from Erwinia carotovora (EwA), a promising antitumor agent. New branched copolymers of d
Publikováno v:
Biochemistry. Biokhimiia. 80(1)
Conjugation with the new branched copolymers, PEG-chitosan and glycol-chitosan, is suggested to improve the therapeutic properties of L-asparaginase from Erwinia carotovora (EwA). The structure and composition of such conjugates were optimized for ma