Zobrazeno 1 - 10
of 23
pro vyhledávání: '"K. V. Shur"'
Publikováno v:
Russian Journal of Genetics. 57:114-116
Emergence of drug-resistance to antituberculosis agents is a global challenge that requires development of novel drugs, active against resistant Mycobacterium tuberculosis strains. One of the tasks of drug development is to determine the mechanism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f8199382674b922b30ad2670e16ffb1
https://doi.org/10.1134/s1022795421010154
https://doi.org/10.1134/s1022795421010154
Autor:
Olga B. Bekker, Valery N. Danilenko, Alexey A. Vatlin, Rashida I. Ishmetova, N. K. Ignatenko, Svetlana G. Tolshchina, Anna V. Korotina, Gennady L. Rusinov, D. A. Maslov, Valery N. Charushin, K. V. Shur
Publikováno v:
European Journal of Medicinal Chemistry. 178:39-47
Tuberculosis (TB) has recently become the leading killer among infectious diseases. Multidrug and extensively drug-resistant Mycobacterium tuberculosis strains urge the need to develop anti-TB drugs with a novel mechanism of action. We describe synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc99160eb5f0e6af9fdd3fa2335567ab
https://doi.org/10.1016/j.ejmech.2019.05.081
https://doi.org/10.1016/j.ejmech.2019.05.081
Publikováno v:
Bulletin of Russian State Medical University. :5-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffd0105a4b194b3e3b003c9ca393fda3
https://doi.org/10.24075/brsmu.2018.038
https://doi.org/10.24075/brsmu.2018.038
Autor:
A. V. Korotina, Valery N. Danilenko, Olga B. Bekker, K. V. Shur, Aleksey A. Vatlin, D. A. Maslov
Publikováno v:
Bulletin of Russian State Medical University. :19-22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b371b24eeeaf4d81cc50b5b72454e343
https://doi.org/10.24075/brsmu.2018.039
https://doi.org/10.24075/brsmu.2018.039
Autor:
N. I. Akimova, Olga B. Bekker, D. A. Maslov, K. V. Shur, Valery N. Danilenko, N. E. Mikheecheva
Publikováno v:
Russian Journal of Genetics. 53:1006-1015
The M. tuberculosis resistome includes a number of genes involved in intrinsic drug resistance. One of the major members of this system is the whiB7 gene encoding a transcription factor, which regulates expression of a number of genes—its regulon.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2152de9f26e7406d9702dba31abbbb5
https://doi.org/10.1134/s1022795417080087
https://doi.org/10.1134/s1022795417080087
Publikováno v:
Bulletin of Russian State Medical University. :44-47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba41a52c256205899295dce5d8599dc8
https://doi.org/10.24075/brsmu.2017-01-05
https://doi.org/10.24075/brsmu.2017-01-05
Autor:
D. A. Maslov, Roman A. Yunes, Natalia V. Zakharevich, Natalia I. Akimova, K. V. Shur, Svetlana Frolova, Valery N. Danilenko
Publikováno v:
Microbiology Resource Announcements
Here, we report the draft genome sequences of 15 Mycobacterium tuberculosis isolates of the Beijing-B0/W-148 sublineage that carry a 7-bp insertion within the pks15 gene, which leads to the synthesis of Pks15/1 fusion protein. Pks15/1 is involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb32854efd3daf0c01ec9b059e228c3
https://doi.org/10.1128/mra.01126-19
https://doi.org/10.1128/mra.01126-19
Autor:
Natalia V. Zakharevich, D. A. Maslov, K. V. Shur, M. V. Zaychikova, Olga B. Bekker, Valery N. Danilenko
Publikováno v:
Microbiology Resource Announcements
We report the draft genome sequences of three Mycobacterium tuberculosis isolates belonging to the B0/N-90 sublineage, EKB34, EKB53, and EKB79. The B0/N-90 sublineage belongs to the prevalent (in Russia) and highly virulent Beijing-B0/W148 sublineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70654056d00fab825e10716cf034ad94
https://pubmed.ncbi.nlm.nih.gov/31558630
https://pubmed.ncbi.nlm.nih.gov/31558630
Publikováno v:
Microbiology Resource Announcements
Here, we report 12 draft genome sequences of mutant Mycolicibacterium smegmatis strains resistant to imidazo[1,2-b][1,2,4,5]tetrazines, which are antituberculosis drug candidates. We have identified 7 different mutations in the MSMEG_1380 gene, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d82d77045e093bc9df2f804ed51d344
http://europepmc.org/articles/PMC6473147
http://europepmc.org/articles/PMC6473147
Autor:
K. V. Shur, Shuo Zhang, Jiayun Liu, Ying Zhang, D. A. Maslov, Valery N. Danilenko, Wanliang Shi, Olga B. Bekker, Gail Cassell, Xiaoke Hao
Although drug resistance inM. tuberculosisis mainly caused by mutations in drug activating enzymes or drug targets, there is increasing interest in possible role of efflux in causing drug resistance. Previously, efflux genes are shown upregulated upo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb7b0744d5d149bfed33c741fd658ab
