Zobrazeno 1 - 10
of 11
pro vyhledávání: '"K. V. Lapshina"'
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 58:2035-2047
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 57:1060-1071
The stress-inducible 70 kDa heat shock protein (Hsp70) can exert a protective effect on endotoxemia and sepsis due to its ability to interact with immune cells and modulate the immune response. However, it remains unknown whether Hsp70 is able to rel
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology
The stress-inducible 70 kDa heat shock protein (Hsp70) can exert a protective effect on endotoxemia and sepsis due to its ability to interact with immune cells and modulate the immune response. However, it remains unknown whether Hsp70 is able to rel
Autor:
Yu. F. Pastukhov, I. V. Ekimova, V. V. Simonova, M. V. Chernyshev, K. V. Lapshina, M. A. Guzeev
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 52:463-474
Numerous experimental and epidemiological data indicate a high significance of environmental neurotoxins, specifically, inhibitors of the ubiquitin–proteasome system, in pathogenesis of Parkinson’s disease (PD). To develop a preclinical model of
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 52:161-167
It was shown previously that sleep deprivation in representatives of warm-blooded animals evokes an elevation of the glucose-regulated protein 78 (Grp78) gene expression in the brain structures involved in the control of sleep and thermoregulation. H
Autor:
I. V. Ekimova, K. V. Lapshina
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 46:461-470
Electroencephalographic methods were used to study effects of preparation of the exogenous heat shock protein with molecular mass of 70 kDa (Hsp70i/Hsc70) on time characteristics of sleep and wakefulness, brain temperature, peripheral vasomotor react
Publikováno v:
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. 457(1)
According to modern views, impairment of protein folding is a serious danger for cell survival and a molecular basis for neurodegeneration (1, 2). A decrease in the activity of the ubiquitin proteasome system, which is responsible for disposal of mis
Autor:
Iu F, Pastukhov, I V, Ekimova, D A, Meshalkina, M A, Guzeev, M V, Chernyshov, K V, Lapshina, E A, Lukina, V F, Lazarev, K A, Khudik, I V, Guzhova
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 98(12)
Data obtained for the last 12 years and modern hypotheses on key function of sleep and the role of Heat Shock Protein 70 kDa (HSP70) molecular chaperones family in sleep modulation are insufficient to determine assotiation of sleep quantity to the le
Autor:
K V, Lapshina, I V, Ekimova
Publikováno v:
Zhurnal evoliutsionnoi biokhimii i fiziologii. 46(5)
Electroencephalographic methods were used to study effects of the preparation of the exogenous heat shock protein with molecular mass 70 kDa (Hsp70i/Hsc70) on the time characteristics of sleep and waking, brain temperature, peripheral vasomotor react
Autor:
K V, Lapshina, I V, Ekimova
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 95(2)
Using electrophysiological methods, the effects of total sleep deprivation on thermoregulatory characteristics of the febrile reaction (brain temperature, peripheral vasomotor reaction, contractile activity of the pectoral muscle), the process of reh