Zobrazeno 1 - 10 of 82 pro vyhledávání: '"K. V. Honn"'
2
Role of eicosanoids in prostate cancer progression
Autor: D, Nie, M, Che, D, Grignon, K, Tang, K V, Honn
Publikováno v: Cancer metastasis reviews. 20(3-4)
Metabolism of arachidonic acid through cyclooxygenase, lipoxygenase, or P450 epoxygenase pathways leads to the formation of various bioactive eicosanoids. In this review, we discuss alterations in expression pattern of eicosanoid-generating enzymes f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::010c48dbbcbf6cdf19364a5b40173d98
https://pubmed.ncbi.nlm.nih.gov/12085962
Zobrazit plný text záznamu
3
Ectopic alphaIIbbeta3 integrin signaling involves 12-lipoxygenase- and PKC-mediated serine phosphorylation events in melanoma cells
Autor: E, Rásó, J, Tóvári, K, Tóth, S, Paku, M, Trikha, K V, Honn, J, Tímár
Publikováno v: Thrombosis and haemostasis. 85(6)
Megakaryocytic genes such as alphaIIbbeta3 can be expressed by malignant cells as part of the disturbances in their gene regulation. However, the function of the gene product greatly depends on the interaction of the ectopic protein with the new envi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e73300b126771ad93c24a7dbc27e434d
https://pubmed.ncbi.nlm.nih.gov/11434681
Zobrazit plný text záznamu
7
12-lipoxygenase expression in human melanoma cell lines
Autor: J, Timár, E, Rásó, K V, Honn, W, Hagmann
Publikováno v: Advances in experimental medicine and biology. 469
12-lipoxygenase (12-LOX) expression and function in the regulation of the metastatic phenotype was demonstrated in several murine melanoma lines before. Here we have provided novel evidences that, though at a low level (in max. 15% of the cell popula
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b8a677c62c7b323109333067baff0ee9
https://pubmed.ncbi.nlm.nih.gov/10667390
Zobrazit plný text záznamu
8
A novel hydroxamic acid compound, BMD188, demonstrates anti-prostate cancer effects by inducing apoptosis. II: In vivo efficacy and pharmacokinetic studies
Autor: L, Li, Z, Zhu, B, Joshi, C, Zhang, C R, Johnson, L J, Marnett, K V, Honn, J D, Crissman, A T, Porter, D G, Tang
Publikováno v: Anticancer research. 19(1A)
In the preceding paper, we demonstrated that, BMD188 [cis-1-hydroxy-4-(1-naphthyl)-6-octylpiperidine-2-one], a newly synthesized cyclic hydroxamic acid compound, induces potent apoptotic death of prostate cancer cells in vitro. In this project, we st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eeef96dc421e367ec98a739a76466030
https://pubmed.ncbi.nlm.nih.gov/10226525
Zobrazit plný text záznamu
9
Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth
Autor: D, Nie, G G, Hillman, T, Geddes, K, Tang, C, Pierson, D J, Grignon, K V, Honn
Publikováno v: Cancer research. 58(18)
Previously, we found a positive correlation between the expression of platelet-type 12-lipoxygenase (12-LOX) and the progression of human prostate adenocarcinoma (PCa; Gao et al., Urology, 46: 227-237, 1995). To determine the role of 12-LOX in PCa pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f08f0aaf2bf08a4c789d489d6d4a672b
https://pubmed.ncbi.nlm.nih.gov/9751607
Zobrazit plný text záznamu
10
12(S)-hydroxyeicosatetraenoic acid increases the actin microfilament content in B16a melanoma cells: a protein kinase-dependent process
Autor: R L, Rice, D G, Tang, M, Haddad, K V, Honn, J D, Taylor
Publikováno v: International journal of cancer. 77(2)
12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE], a lipoxygenase metabolite of arachidonic acid, has been shown to be involved in a wide variety of cellular activities (i.e., adhesion, spreading, motility, invasion) which promote metastasis to occur i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d65c7e1508dff9e4e2c1aece068a9e32
https://pubmed.ncbi.nlm.nih.gov/9650564
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje