Zobrazeno 1 - 10
of 23
pro vyhledávání: '"K. V. Bolshakov"'
Publikováno v:
Acta Naturae. 9:75-80
The interaction of TRPV1-receptors agonists (capsaicin and protons) has been studied on cultured CHO cells transfected by TRPV1-receptors. Using the whole-cell patch-clamp approach, it was shown that summation of the currents induced by agonist appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60f731ff6902843ec8629085a945bb2e
https://doi.org/10.32607/20758251-2017-9-1-75-80
https://doi.org/10.32607/20758251-2017-9-1-75-80
Autor:
Denis B. Tikhonov, Elina I. Nagaeva, Oleg I. Barygin, Tatiana B. Tikhonova, K. V. Bolshakov, Natalia N. Potapieva
Publikováno v:
Neuropharmacology. 89:1-10
Acid-sensing ion channels (ASICs) are widely distributed in the peripheral and central nervous system. Although they are involved in many physiological functions, the actual processes that activate ASICs remain unclear. This is particularly true for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ad80bacb5e98fa68cb709f29aed0e9
https://doi.org/10.1016/j.neuropharm.2014.08.018
https://doi.org/10.1016/j.neuropharm.2014.08.018
Publikováno v:
Acta Naturae
The interaction of TRPV1-receptors agonists (capsaicin and protons) has been studied on cultured CHO cells transfected by TRPV1-receptors. Using the whole-cell patch-clamp approach, it was shown that summation of the currents induced by agonist appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08d5b3f729cfd3ca9758b2f1158e1206
https://pubmed.ncbi.nlm.nih.gov/28461977
https://pubmed.ncbi.nlm.nih.gov/28461977
Autor:
K. V. Bolshakov, M. V. Nikolaev
Publikováno v:
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology. 4:302-308
It is well known that not all effects of such classical NMDA receptor channel blockers as spermine and phylantotoxins are madiated via channel blockade. To determine if these side effects have any functional role we studied inhibition of NMDA recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::800a4ce3a185abdf8283bd8cc90efe14
https://doi.org/10.1134/s1990747810030098
https://doi.org/10.1134/s1990747810030098
Autor:
Oleg I. Barygin, K. V. Bolshakov, Natalia A. Dorofeeva, Lev G. Magazanik, Alexander Staruschenko
Publikováno v:
Journal of Neurochemistry. 106:429-441
The inhibitory action of non-steroid anti-inflammatory drugs was investigated on acid-sensing ionic channels (ASIC) in isolated hippocampal interneurons and on recombinant ASICs expressed in Chinese hamster ovary (CHO) cells. Diclofenac and ibuprofen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d176397bc4faaadfc5fb2a60912699
https://doi.org/10.1111/j.1471-4159.2008.05412.x
https://doi.org/10.1111/j.1471-4159.2008.05412.x
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 355(3)
To evaluate the possible role of the plasma membrane Na(+)/Ca(2+)-exchanger (NCX) in regulation of N-methyl-d-aspartate (NMDA) receptors (NMDARs), we studied effects of 2-[2-[4-(4-nitrobenzyloxy) phenyl]ethyl]isothiourea methanesulfonate (KB-R7943; K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c7cfcf3c1aacd1dc8287033f15eb37
https://pubmed.ncbi.nlm.nih.gov/26391160
https://pubmed.ncbi.nlm.nih.gov/26391160
Publikováno v:
Developmental Neurobiology. 67:97-107
Acid-sensing ion channels (ASIC) are ligand-gated cation channels that are highly expressed in peripheral sensory and central neurons. ASIC are transiently activated by decreases in extracellular pH and are thought to play important roles in sensory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41bc4d3713a89a171ddc22501a5beb08
https://doi.org/10.1002/dneu.20338
https://doi.org/10.1002/dneu.20338
Autor:
K. V. Bolshakov, P.N.R. Usherwood, Lev G. Magazanik, Natalia N. Potapjeva, Denis B. Tikhonov, K. H. Kim, Ian R. Mellor, V. E. Gmiro
Publikováno v:
Neuropharmacology. 49:144-155
Determinants of antagonism of NMDA and calcium permeable AMPA receptor channels by organic cations were studied using several homologous series of mono- and dicationic derivatives of adamantane, phenylcyclohexyl, triphenylmethane, diphenylmethane. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1b0fe28f8f752bdb6a398d902c5dc7
https://doi.org/10.1016/j.neuropharm.2005.02.007
https://doi.org/10.1016/j.neuropharm.2005.02.007
Autor:
N. I. Rukoyatkina, K. V. Bolshakov, L. V. Gorbunova, V. E. Gmiro, Lev G. Magazanik, N. Ya. Lukomskaya
Publikováno v:
Neuroscience and Behavioral Physiology. 34:181-187
The abilities of mono- and dicationic adamantane and phenylcyclohexyl derivatives to (a) block open NMDA and AMPA glutamate receptors in isolated rat brain neurons and (b) prevent convulsions induced in mice by intraventricular NMDA or kainate were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052ec0b21c09c33d0ee193f7dcaa3b94
https://doi.org/10.1023/b:neab.0000009212.61235.ed
https://doi.org/10.1023/b:neab.0000009212.61235.ed
Publikováno v:
Journal of Neurochemistry. 87:56-65
Open channel blockers of NMDA receptors interact with the channel gate in different ways. Compounds like MK-801 and phencyclidine exhibit pronounced trapping block, whereas 9-aminoacridine and tetrapentylammonium cannot be trapped. Some blockers such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ad35699bfe5325f070863b8514bdc14
https://doi.org/10.1046/j.1471-4159.2003.01956.x
https://doi.org/10.1046/j.1471-4159.2003.01956.x