Zobrazeno 1 - 10
of 37
pro vyhledávání: '"K. Ulrich Wendt"'
Autor:
Hai-Yu Hu, Danping Ding-Pfennigdorff, Ngee Han Lim, Joachim Saas, K. Ulrich Wendt, Hideaki Nagase, Marc Nazaré, Carsten Schultz, Oliver Plettenburg, olaf Ritzeler
Publikováno v:
Bioconjugate Chemistry. 26:383-388
Targeted drug-delivery methods are crucial for effective treatment of degenerative joint diseases such as osteoarthritis (OA). Toward this goal, we developed a small multivalent structure as a model drug for the attenuation of cartilage degradation.
Autor:
Matej Vizovišek, K. Ulrich Wendt, Divya Vats, Lovro Kramer, Hai-Yu Hu, Boris Turk, Markus Rudin, Oliver Plettenburg, Catherine Germanier, Carsten Schultz
Publikováno v:
Angewandte Chemie. 126:7802-7806
Die Synthese und Anwendung zweier fr Cathep- sin S spezifischer Sonden wird beschrieben. Um den langfris- tigen Verbleib der Sonden am Zielort und eine hohes Signal/ Rausch-Verhltnis zu erzielen, wurde ein Lipidierungsansatz �ber das Einfgen eines
Autor:
Markus Rudin, Oliver Plettenburg, Carsten Schultz, Matej Vizovišek, K. Ulrich Wendt, Catherine Germanier, Divya Vats, Boris Turk, Hai-Yu Hu, Lovro Kramer
Publikováno v:
Angewandte Chemie (International ed. in English)
Angewandte Chemie. International Edition, 53 (29)
Angewandte Chemie (International Ed. in English)
Angewandte Chemie. International Edition, 53 (29)
Angewandte Chemie (International Ed. in English)
The synthesis and evaluation of two cathepsin S-specific probes is described. For long-term retention of the probe at the target site and a high signal-to-noise ratio, we introduced a lipidation approach via the simple attachment of palmitoic acid to
Autor:
Kanchan Anand, Trine Christensen, Josep Vendrell, K. Ulrich Wendt, Herman Schreuder, Irantzu Pallarès, Zuzana Valnickova, Jan J. Enghild, Francesc X. Avilés
Publikováno v:
Journal of Biological Chemistry. 283:29416-29423
Mature thrombin-activable fibrinolysis inhibitor (TAFIa) is a highly unstable metallocarboxypeptidase that stabilizes blood clots by clipping C-terminal lysine residues from partially degraded fibrin. In accordance with its in vitro antifibrinolytic
Autor:
Boris Turk, Anja Watzke, Vito Turk, Volker Jeske, Hans-Peter Nestler, Gregor Kosec, K. Ulrich Wendt, Maik Kindermann
Publikováno v:
Angewandte Chemie. 120:412-415
Autor:
Gregor Kosec, Boris Turk, Volker Jeske, Anja Watzke, K. Ulrich Wendt, Vito Turk, Maik Kindermann, Hans-Peter Nestler
Publikováno v:
Angewandte Chemie International Edition. 47:406-409
Autor:
Bettina Elshorst, Gerhard Hessler, Alexander Schiffer, Isabelle Krimm, Thomas Langer, Donghan Lee, Stefan Bartoschek, Adam Mazur, Peter Monecke, Christian Griesinger, Jens Pilger, Herman Schreuder, K-Ulrich Wendt, Stefan Becker, Melanie Wegstroth
Publikováno v:
Angewandte Chemie
Angewandte Chemie, Wiley-VCH Verlag, 2015, 54 (22), pp.6511-6515. ⟨10.1002/anie.201500671⟩
Angewandte Chemie International Edition
Angewandte Chemie, Wiley-VCH Verlag, 2015, 54 (22), pp.6511-6515. ⟨10.1002/anie.201500671⟩
Angewandte Chemie International Edition
We thank Sandra Schimanski-Breves and Alexander Liesum for crystallization, Dirk Bossemeyer and Michael Gassel for protein production of PKA.; International audience; Structure-based drug design (SBDD) is a powerful and widely used approach to optimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4722c0ab9ba3f3847d29d0db92064d
https://hal.archives-ouvertes.fr/hal-01165216
https://hal.archives-ouvertes.fr/hal-01165216
Autor:
Hans Paul Juretschke, Hai-Yu Hu, K. Ulrich Wendt, Ngee Han Lim, Peter Florian, Oliver Plettenburg, Markus Kohlmann, Karl A. Rudolphi, Joachim Saas, Carsten Schultz, Marc Nazaré, Danping Ding-Pfennigdorff, Hideaki Nagase, Jens Peter von Kries, Abdullah Kandira
Publikováno v:
Chemical science, 6(11): 6256-6261
Osteoarthritis (OA) is one of the most common diseases in the aging population. While disease progress in humans is monitored indirectly by X-ray or MRI, small animal OA lesions detection always requires surgical intervention and histology. Here we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9f74dcca5694da33ee2021efc7c880
https://repository.publisso.de/resource/frl:6405030
https://repository.publisso.de/resource/frl:6405030
Autor:
Ulrich Schieborr, Swen Hoelder, Harald Schwalbe, Barbara Pescatore, Laure Delarbre, Krishna Saxena, Michel Robin, Susanne Grimme, Thomas Langer, Martin Vogtherr, Marco Betz, K. Ulrich Wendt
Publikováno v:
Angewandte Chemie. 118:1008-1012
Publikováno v:
ChemBioChem. 7:203-208